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Cancer: Carcinoma
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Total 3164 results found since Jan 2013.
Durable complete response to early immunotherapy discontinuation in a kidney transplant recipient with advanced cutaneous squamous cell carcinoma: A case report and review of literature
CONCLUSION: Organ transplant recipients with complete response to immunotherapy for cutaneous squamous cell carcinoma may continue to respond despite early treatment cessation. This may reduce the risks of late immune-related adverse events and acute graft rejection.PMID:37734447 | DOI:10.1016/j.trim.2023.101932
Source: Transplant Immunology - September 21, 2023 Category: Transplant Surgery Authors: Ziyao Lu Mohammed Afzal Keisuke Shirai Source Type: research
Intratumoral Bacteria as Mediators of Cancer Immunotherapy Response
Cancer Res. 2023 Sep 15;83(18):2985-2986. doi: 10.1158/0008-5472.CAN-23-1857.ABSTRACTMultiple lines of evidence spanning from animal models to human clinical trials indicate that the microbiome influences cancer immunotherapy response. Whereas initial studies focused exclusively on the gastrointestinal (gut) microbiota-tumor axis, more recent studies have examined the possibility that bacteria located within tumor cells or within the tumor microenvironment mediate cancer treatment response. Strikingly, this phenomenon has been demonstrated in cancers that arise in anatomic locations that are traditionally thought to be dev...
Source: Cell Research - September 15, 2023 Category: Cytology Authors: Karen S Sfanos Source Type: research
Exploring Cardiac Impact of Oral Nicotine Exposure in a Transplantable Neoplasm Mice Model: Insights from Biochemical Analysis, Morphometry, and Molecular Docking: Chlorella vulgaris Green Algae Support
This study was designed to investigate the impact of nicotine and Chlorella vulgaris (Ch. V) on cardiac glutathione homeostasis, inflammatory response, cardiac damage markers, apoptotic proteins and histopathological findings in an experimentally transplantable neoplasm mouse model (Ehrlich ascites carcinoma; EAC). In the in-vivo experiment, the female Swiss mice were divided into four groups: control, Ch.V (100mg/kg), Nicotine (100µg/ml/kg), and a combination group ( Nocotine+ Ch.V) for 40 days. Furthermore, the effects of C. vulgaris components on caspase-3, TNF-α, and IL-1β activity were explored using Molecular Oper...
Source: Toxicology - September 13, 2023 Category: Toxicology Authors: Amany Abdel-Rahman Mohamed Gihan G Moustafa Khlood M El Bohy Taghred M Saber Mohamed M M Metwally Heba El Desoukey Mohammed Ali H El-Far Badriyah S Alotaibi Manal Alosaimi Samah S Abuzahrah Leena S Alqahtani Source Type: research
Comparative Analysis of Donor Liver Allograft Outcomes in Hepatocellular Carcinoma Patients Who Underwent Liver Transplant
CONCLUSIONS: Similar outcomes can be achieved for hepatocellular carcinoma patients who undergo liver transplant with donations after brain death, donations after cardiac death, or donations after brain and cardiac death allografts, especially when strict donor selection criteria are applied.PMID:37698401 | DOI:10.6002/ect.2023.0119
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - September 12, 2023 Category: Transplant Surgery Authors: Abdulahad Abdulrab Mohammed Al-Ameri Zhisheng Zhou Shusen Zheng Source Type: research
Liver Transplantation for Hepatocellular Carcinoma in Patients with Inherited Metabolic Liver Diseases: A Single-Center Analysis
CONCLUSION: Liver transplant for these categories of patients is associated with good disease-free and overall survival, even in the presence of some seemingly poor prognostic features.PMID:37681267 | DOI:10.5152/tjg.2023.22679
Source: The Turkish Journal of Gastroenterology - September 8, 2023 Category: Gastroenterology Authors: İbrahim Umar Garzali Abdirahman Sakulen Hargura Volkan İnce Fatma İlknur Varol Brian I Carr Sezai Y ılmaz Source Type: research
