• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Young nasopharyngeal cancer patients with radiotherapy and chemotherapy are most prone to ischaemic risk of stroke: a national database, controlled cohort study
ConclusionsPatients with nasopharyngeal carcinoma are at an elevated risk of ischaemic stroke, without significant difference among treatment modalities. The relative risk is more prominent in younger patients. Comorbidity may enhance the risk.
Source: Clinical Otolaryngology - February 19, 2013 Category: ENT & OMF Authors: Chu C.‐N., Chen P.‐C., Bai L.‐Y., Muo C.‐H., Sung F.‐C., Chen S.‐W. Tags: Original Article Source Type: research

Risk of Stroke After Definitive Radiotherapy —Cause for Concern or Modest Risk?
With the rapidly increasing prevalence of oropharyngeal squamous cell carcinoma (OPSCC), largely driven by the human papillomavirus (HPV) epidemic, and with relative equipoise between radiation-based and surgery-based treatment protocols, there has been renewed interest in describing differences in functional outcomes between the 2 treatment modalities. Radiation is theoretically related to stroke risk due to carotid artery intimal injury, which could lead to the development of atherosclerosis. Both carotid artery stenosis and carotid intima-medial thickness have been shown to be associated with radiation therapy providing...
Source: JAMA Otolaryngology - Head and Neck Surgery - June 23, 2022 Category: ENT & OMF Source Type: research

Up-front Surgery and Risk of Stroke in US Veterans With Oropharyngeal Carcinoma
This cohort study evaluates the association of up-front surgery and stroke risk compared with nonsurgical treatment for oropharyngeal squamous cell carcinoma among US veterans.
Source: JAMA Otolaryngology - Head and Neck Surgery - June 23, 2022 Category: ENT & OMF Source Type: research

Evaluation of Reconstructive Techniques for Anterior and Middle Skull Base Defects Following Tumor Ablation
Conclusions: Vascularized flaps provide reliable and durable reconstructive options for anterior and middle skull base defects after resection of large complex malignant neoplasms of the craniofacial region. Free flaps, such as RFFFs, ALTs, and TDAPs, are well suited for these defects. They have a low risk of complications and low donor-site morbidity and offer good functional and esthetic outcomes.
Source: Journal of Oral and Maxillofacial Surgery - July 15, 2013 Category: ENT & OMF Authors: Jayini S. Thakker, Rui Fernandes Tags: Surgical Oncology and Reconstruction Source Type: research

Simultaneous carotid endarterectomy and free flap surgery for head and neck microvascular reconstruction
Introduction/aims: Microvascular free flaps are the gold standard for reconstruction of head and neck defects. However, suitable recipient vessels are essential. Stenosis of the carotid tree is most commonly due to atherosclerosis, which shares risk factors with head and neck squamous cell carcinoma. Free flaps are often not carried out in these patients due to the risk of failure and complications. Carotid endarterectomy (CEA) offers an evidence based intervention for stroke risk reduction but its use for improving vascularity to free flaps has not been previously reported.
Source: The British Journal of Oral and Maxillofacial Surgery - December 1, 2015 Category: ENT & OMF Authors: N. Opie, N. Pattni, S. Colley, M. Simms, P. Praveen, T. Martin, S. Parmar Tags: P 76 Source Type: research

Cardiac comorbidity in head and neck cancer patients and its influence on cancer treatment selection and mortality: a prospective cohort study
AbstractComorbidity assessment and a profound cardiac examination were implemented into pre-treatment diagnostics to analyze their influence on head and neck squamous cell carcinoma (HNSCC) therapy selection and short-term mortality. Comorbidity was measured prospectively in 49 HNSCC patients using standard indices between 2012 and 2013. Cardiac examinations included electrocardiogram, echocardiography, and bicycle ergometry. Most patients had stage IV tumors (61  %), smoked (61 %), and showed alcohol abuse (57 %); 38 patients (78 %) received a multimodal therapy; 65 % had an adult comorbidity evaluation 27 index ≥2...
Source: European Archives of Oto-Rhino-Laryngology - August 4, 2016 Category: ENT & OMF Source Type: research

Bilateral lingual artery stenosis: A rare, late complication of chemoradiotherapy
Discussion Small vessel disease is a possible complication in patients treated by RT for head and neck cancer. Although the risk of these complications is not directly related to the total radiation dose, higher doses appear to accelerate the development of vascular lesions. Practitioners must be aware of the possibility of these complications, especially in patients surviving more than 5 years.
Source: European Annals of Otorhinolaryngology, Head and Neck Diseases - March 10, 2017 Category: ENT & OMF Source Type: research

Diagnosis and Treatment of Squamous Cell Carcinoma in Lower Lip: Case Report
A 67-year-old woman attended the stomatology clinic complaining of a wound on the lip, painful, with an evolution of 3 months. During this period, she was treated by a dermatologist for herpes simplex, but without resolution. Anamnesis indicated systemic arterial hypertension and previous stroke; she denied smoking or performing activities causing sun exposure. A physical examination revealed an exophytic ulcer on the lower lip with a crusted necrotic background, indurated rounded borders, soft base, 1.5  cm in size, and loss of the mucocutaneous line.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - September 1, 2018 Category: ENT & OMF Authors: Rayane Velloso De Almeida, Miriam Beatriz Jord ão Moreira Sarruf, Ana Flávia Schuler De Assumpção Leite, Adriana Terezinha Neves Novellino Alves, Simone De Queiroz Chaves Lourenço, Jacqueline Tavares Silva Fernandes, Josiane Costa Rodrigues De Sá Tags: Oral and Maxillofacial Pathology Source Type: research

A Study on Etiopathogenesis of Vocal Cord Paresis and Palsy in a Tertiary Centre
AbstractTo identify patients of vocal cord paresis and palsy and to establish an etiological diagnosis based on a study performed in a tertiary centre. Study was done prospectively in the Department of ENT in KIMS Hospital, Bangalore, for 1  year, from June 2016 to June 2017. 100 patients with vocal cord paresis and palsy were identified and examined by using various tests and investigations to establish the etiology. Most of the patients presented with complaints of change in voice (92%). Some of the other common presenting complaint s included noisy breathing and difficulty in swallowing, difficulty in voice production ...
Source: Indian Journal of Otolaryngology and Head and Neck Surgery - October 8, 2018 Category: ENT & OMF Source Type: research

The basaloid variant of squamous cell carcinoma in an uncommon location
Microscopic aspects of basaloid squamous cell carcinoma (BSCC) are well defined, and its prevalence is rare in the mouth. Current research points to similarity of its course in relation to conventional squamous cell carcinoma; however, there is lack of information about its clinical behavior and prognosis. An 83-year-old male patient complained of a “lump inside the mouth,” noticed 4 months ago. Medical history revealed heart failure, systemic arterial hypertension, Alzheimer’s disease, history of stroke, and smoking (2 packs a day) for 30 years, discontinued 20 years ago.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - August 31, 2020 Category: ENT & OMF Authors: GABRIELA MOURA CHICRALA, RAQUEL D ’AQUINO GARCIA CAMINHA, SILAS ANTONIO JUVENCIO DE FREITAS FILHO, DENISE TOSTES OLIVEIRA, PAULO SÉRGIO DA SILVA SANTOS Tags: 20190182 Source Type: research

Errors in Figure 3 and Table 2
This article has been corrected.
Source: JAMA Otolaryngology - Head and Neck Surgery - January 12, 2023 Category: ENT & OMF Source Type: research

Risk of Cardiovascular Events Among Patients With Head and Neck Cancer
This cohort study examines cardiovascular risk profiles, incident stroke, myocardial infarction, and mortality in US veterans with head and neck squamous cell carcinoma.
Source: JAMA Otolaryngology - Head and Neck Surgery - June 22, 2023 Category: ENT & OMF Source Type: research