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Total 679 results found since Jan 2013.

Transcriptomic Analysis in Renal Cell Carcinoma and COVID-19 patients
Cell Mol Biol (Noisy-le-grand). 2023 Aug 31;69(8):156-162. doi: 10.14715/cmb/2023.69.8.24.ABSTRACTCOVID-19 pandemic poses a heavy risk upon global public health. The disease's severity and infection rate are high, especially among cancer patients. The current research was conducted to identify the most common biological pathways and how far they are associated with COVID-19 infection and clear cell renal cell carcinoma. In the current study, the authors analyzed the differentially expressed genes from the experimental and control groups with the help of the GEO2R tool. The study analyzed the protein-protein interactions th...
Source: Mol Biol Cell - September 16, 2023 Category: Molecular Biology Authors: Maha Abdulla Alwaili Source Type: research

Melatonin Supplementation for Cancer-Related Fatigue in Patients With Early Stage Breast Cancer Receiving Radiotherapy: A Double-Blind Placebo-Controlled Trial
CONCLUSIONS: In this double-blind placebo-controlled phase III trial, melatonin did not prevent or significantly improve fatigue and other symptoms in patients with early stage breast cancer undergoing RT. The analysis, showing little evidence of an effect, at mid-recruitment, assured early termination of the trial.PMID:37699115 | DOI:10.1093/oncolo/oyad250
Source: The Oncologist - September 12, 2023 Category: Cancer & Oncology Authors: Nitai D Mukhopadhyay Adam Khorasanchi Sudeep Pandey Srinidhi Nemani Gwendolyn Parker Xiaoyan Deng Douglas W Arthur Alfredo Urdaneta Egidio Del Fabbro Source Type: research

Self-reported barriers to screening breast MRI among women at high risk for breast cancer
CONCLUSIONS: High-risk women reported low uptake of screening breast MRI, indicating a gap in guideline-concordant care. Breast cancer knowledge and screening-supportive social norms are two key areas to target in future interventions. Data were collected during the COVID-19 pandemic and generalizability of results is unclear. Future studies with larger, more heterogeneous samples are needed to replicate these findings.PMID:37640965 | DOI:10.1007/s10549-023-07085-w
Source: Cancer Control - August 28, 2023 Category: Cancer & Oncology Authors: Claire C Conley Jennifer D Rodriguez McKenzie McIntyre Naomi C Brownstein Bethany L Niell Suzanne C O'Neill Susan T Vadaparampil Source Type: research

Comprehensively prognostic and immunological analysis of Ubiquitin Specific Peptidase 28 in pan-cancer and identification in hepatocellular carcinoma pan-cancer analysis of USP28
CONCLUSIONS: Our study suggests that USP28 could potentially serve as a biomarker for cancer immunologic infiltration and poor prognosis, with potential applications in developing novel cancer treatment strategies.PMID:37450415 | DOI:10.18632/aging.204869
Source: Aging - July 14, 2023 Category: Biomedical Science Authors: Wuhan Zhou Jiafei Chen Jingui Wang Source Type: research

The parotid gland, an unusual site of colorectal cancer metastasis
We present a case of stage IV sigmoid colon adenocarcinoma with metastases to the left parotid. The patient was a 53-year-old Filipino man diagnosed with stage IV sigmoid adenocarcinoma with liver metastases in June 2021. He underwent laparoscopic sigmoidectomy and received eight cycles of chemotherapy with capecitabine and oxaliplatin with partial response of his liver lesions. Capecitabine monotherapy was then maintained. On September 2022, he experienced persistent left facial pain, with no relief after dental tooth extraction and antibiotics. A computed tomography (CT) scan revealed a 5 × 7 × 6 cm inhomogenous mass i...
Source: Cancer Control - July 3, 2023 Category: Cancer & Oncology Authors: Paula Isabel G Francoa Anna Pascual-Panganiban Source Type: research

Biomaterial-based delivery platforms for transdermal immunotherapy
Biomed Pharmacother. 2023 Jun 27;165:115048. doi: 10.1016/j.biopha.2023.115048. Online ahead of print.ABSTRACTNowadays, immunotherapy is one of the most essential treatments for various diseases and a broad spectrum of disorders are assumed to be treated by altering the function of the immune system. For this reason, immunotherapy has attracted a great deal of attention and numerous studies on different approaches for immunotherapies have been investigated, using multiple biomaterials and carriers, from nanoparticles (NPs) to microneedles (MNs). In this review, the immunotherapy strategies, biomaterials, devices, and disea...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - June 29, 2023 Category: Drugs & Pharmacology Authors: Mohammad Dahri Nima Beheshtizadeh Nasrin Seyedpour Amin Nakhostin-Ansari Faezeh Aghajani Simin Seyedpour Moein Masjedi Fatemeh Farjadian Reza Maleki Khosro Adibkia Source Type: research

Development of Dermatomyositis after Pfizer BioNTeh COVID-19 Vaccine: A Case Report
CONCLUSION: This study underlines the importance of completing the etiological assessment before attributing any adverse reaction to vaccination to maintain optimal patient care.PMID:37317919 | DOI:10.2174/1574886318666230614164607
Source: Current Drug Safety - June 15, 2023 Category: Drugs & Pharmacology Authors: Imen Aouintia Wiem Daly Ghozlane Lakhoua Widd Kaabi Ons Charfi Sana Debbeche Sarrah Kastalli Ahmed Zaiem Sihem El Aidli Source Type: research