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Vaccination: Cervical Cancer Vaccine

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Total 1392 results found since Jan 2013.

Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice
Sci Transl Med. 2023 Mar 3:eabn3464. doi: 10.1126/scitranslmed.abn3464. Online ahead of print.ABSTRACTAs mRNA vaccines have proved to be very successful in battling the coronavirus disease 2019 (COVID-19) pandemic, this new modality has attracted widespread interest for the development of potent vaccines against other infectious diseases and cancer. Cervical cancer caused by persistent human papillomavirus (HPV) infection is a major cause of cancer-related deaths in women, and the development of safe and effective therapeutic strategies is urgently needed. In the present study, we compared the performance of three differen...
Source: Herpes - March 3, 2023 Category: Infectious Diseases Authors: Jamile Ramos da Silva Karine Bitencourt Rodrigues Guilherme Formoso Pelegrin Natiely Silva Sales Hiromi Muramatsu Mari ângela de Oliveira Silva Bruna F M M Porchia Ana Carolina Ramos Moreno Luana Raposo M M Aps Al éxia Adrianne Venceslau-Carvalho Istv à Source Type: research

Knowledge, attitudes and acceptance toward Human papillomavirus (HPV) vaccination: Perspectives of Muslim women and men
CONCLUSION: Omani women and men showed a high level of acceptance and favorable attitude toward HPV vaccination. The study findings support future efforts to implement school and public-level HPV education and a national HPV vaccination program in Oman.PMID:36858872 | DOI:10.1016/j.vaccine.2023.02.063
Source: Vaccine - March 1, 2023 Category: Allergy & Immunology Authors: Salma Al Alawi Omar Al Zaabi Margaret E Heffernan Judie Arulappan Noora Al Hasani Munira Al Baluchi Alia Al Mamari Amani Al Saadi Source Type: research

Beliefs and knowledge related to human papillomavirus (HPV) vaccine among African Americans and African immigrants young adults
CONCLUSION: Barriers to vaccine uptake, limited HPV knowledge, and lack of vaccine recommendation are important factors contributing to low vaccine uptake among Black young adults. Interventions to decrease barriers to HPV vaccination, increase HPV knowledge, address misconceptions, and unfavorable beliefs are needed to promote HPV vaccine uptake.PMID:36854988 | DOI:10.1007/s10552-023-01678-y
Source: Cancer Control - March 1, 2023 Category: Cancer & Oncology Authors: Adebola Adegboyega Omoadoni Obielodan Amanda T Wiggins Mark Dignan Lovoria B Williams Source Type: research

Knowledge, attitudes and acceptance toward Human papillomavirus (HPV) vaccination: Perspectives of Muslim women and men
CONCLUSION: Omani women and men showed a high level of acceptance and favorable attitude toward HPV vaccination. The study findings support future efforts to implement school and public-level HPV education and a national HPV vaccination program in Oman.PMID:36858872 | DOI:10.1016/j.vaccine.2023.02.063
Source: Vaccine - March 1, 2023 Category: Allergy & Immunology Authors: Salma Al Alawi Omar Al Zaabi Margaret E Heffernan Judie Arulappan Noora Al Hasani Munira Al Baluchi Alia Al Mamari Amani Al Saadi Source Type: research

Highlights into historical and current immune interventions for cancer
Int Immunopharmacol. 2023 Feb 27;117:109882. doi: 10.1016/j.intimp.2023.109882. Online ahead of print.ABSTRACTImmunotherapy is an additional pillar when combined with traditional standards of care such as chemotherapy, radiotherapy, and surgery for cancer patients. It has revolutionized cancer treatment and rejuvenated the field of tumor immunology. Several types of immunotherapies, including adoptive cellular therapy (ACT) and checkpoint inhibitors (CPIs), can induce durable clinical responses. However, their efficacies vary, and only subsets of cancer patients benefit from their use. In this review, we address three goal...
Source: International Immunopharmacology - February 27, 2023 Category: Allergy & Immunology Authors: Kathryn Cole Zaid Al-Kadhimi James E Talmadge Source Type: research

Optimal size of DNA encapsidated by plant produced human papillomavirus pseudovirions
Virology. 2023 Feb 12;580:88-97. doi: 10.1016/j.virol.2023.02.003. Online ahead of print.ABSTRACTHuman papillomaviruses (HPVs) are known to be the cause of anogenital and oropharyngeal cancers as well as genital and common warts. HPV pseudovirions (PsVs) are synthetic viral particles that are made up of the L1 major and L2 minor HPV capsid proteins and up to 8 Kb of encapsidated pseudogenome dsDNA. HPV PsVs are used to test novel neutralising antibodies elicited by vaccines, for studying the virus life cycle, and potentially for the delivery of therapeutic DNA vaccines. HPV PsVs are typically produced in mammalian cells, h...
Source: Virology - February 21, 2023 Category: Virology Authors: Ayesha Adams Megan Hendrikse Edward P Rybicki Inga I Hitzeroth Source Type: research

Impact of including boys in the national school-based human papillomavirus vaccination programme in Singapore: A modelling-based cost-effectiveness analysis
Vaccine. 2023 Feb 14:S0264-410X(23)00160-3. doi: 10.1016/j.vaccine.2023.02.025. Online ahead of print.ABSTRACTGlobally, gender-neutral Human Papillomavirus (HPV) vaccination programmes are gaining traction. Although cervical cancer remains the most prevalent, other HPV-related cancers are increasingly recognised as important, especially among men who have sex with men. We assessed if including adolescent boys in Singapore's school-based HPV vaccination programme is cost-effective from the healthcare perspective. We adapted a World Health Organization-supported model, Papillomavirus Rapid Interface for Modelling and Economi...
Source: Vaccine - February 16, 2023 Category: Allergy & Immunology Authors: Muhammad Taufeeq Wahab Rayner Kay Jin Tan Alex R Cook Kiesha Prem Source Type: research

Parents' willingness to vaccinate their daughters with human papillomavirus vaccine and associated factors in Debretabor town, Northwest Ethiopia: A community-based cross-sectional study
This study aimed to assess parents' willingness to vaccinate their daughters with Human Papillomavirus vaccine and associated factors in Debre Tabor town. A community-based cross-sectional study was conducted among parents of daughters in Debre Tabor town, and a cluster sampling technique was used to select 738 study participants. A structured and interviewer-administered questionnaire was used to collect the data. Data were entered into EPI data version 4.6 and exported to SPSS version 26 for analysis. Multivariable logistic regression was done and a p-value of ≤ 0.05 was used to declare the level of significance. In th...
Source: Cancer Control - February 16, 2023 Category: Cancer & Oncology Authors: Getie Mihret Aragaw Tazeb Alemu Anteneh Saron Abeje Abiy Mulunesh Abuhay Bewota Getie Lake Aynalem Source Type: research

"If People Were Told About the Cancer, They'd Want to Get Vaccinated": Knowledge, Attitudes, and Beliefs About HPV Vaccination Among Mid-Adult Men
This study aimed to identify knowledge, attitudes, and beliefs (KABs) about HPV and HPV vaccination among newly eligible mid-adult men, for whom uptake in adolescence and younger adulthood remains suboptimal. We conducted six virtual focus groups (N = 34 participants) with unvaccinated men aged 27 to 45 living in Southern California's Inland Empire. Data were systematically analyzed to identify emergent themes using the rigorous and accelerated data reduction technique. The sample of men was diverse (79% Hispanic, non-Hispanic Black, Asian, or mixed race/ethnicity; 26% gay or bisexual) and captured participants from across...
Source: Cancer Control - February 14, 2023 Category: Cancer & Oncology Authors: Raneem A Alaraj Brandon Brown Andrea N Polonijo Source Type: research