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Specialty: Cancer & Oncology
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Total 908 results found since Jan 2013.

Associations of Particulate Matter Exposures With Brain Gray Matter Thickness and White Matter Hyperintensities: Effect Modification by Low-Grade Chronic Inflammation
CONCLUSION: Particulate matter exposures were associated with a reduced global cortical thickness in men with a high level of chronic inflammation. Men with a high level of chronic inflammation may be susceptible to cortical atrophy attributable to particulate matter exposures.PMID:37096314 | DOI:10.3346/jkms.2023.38.e159
Source: Cancer Control - April 25, 2023 Category: Cancer & Oncology Authors: Jaelim Cho Heeseon Jang Young Noh Seung-Koo Lee Sang-Baek Koh Sun-Young Kim Changsoo Kim Source Type: research

Predicted cardiac and second cancer risks for patients undergoing VMAT for mediastinal Hodgkin lymphoma
ConclusionFor patients with mediastinal lymphoma excess mortality risks from CVD and second cancers remain clinically significant despite contemporary chemotherapy and photon-RT. Efforts to reduce the toxicity of combined modality treatment, for example, using DIBH, reduced margins and advanced RT, e.g. proton beam therapy, should be continued to further reduce potentially fatal treatment effects.
Source: Clinical and Translational Oncology - April 23, 2023 Category: Cancer & Oncology Source Type: research

Effect modification of age and hypertension on cancer and prevalence of self ‐reported stroke – A cross‐sectional study
The objective of this study was to examine the effect modification of age on the relationship between cancer and prevalence of self-reported stroke. We used cross-sectional data from the 2015 –2016 iteration of the Canadian Community Health Survey. A multivariable logistic regression model was used to assess the association between cancer and self-reported stroke. Covariates were assessed for effect modification using the maximum likelihood estimation method. We analyzed 86,809 subject s; the prevalence of self-reported stroke was 1.11%. The odds ratio for the association between cancer and self-reported stroke was 1.26 ...
Source: Cancer Medicine - April 21, 2023 Category: Cancer & Oncology Authors: Ronda Lun, Joseph R. Shaw, Danielle Carole Roy, Deborah Siegal, Tim Ramsay, Yue Chen, Dar Dowlatshahi Tags: BRIEF COMMUNICATION Source Type: research

Clinical and Prognostic Relevance of Cardiac Wasting in Patients With Advanced Cancer
CONCLUSIONS: Low LV mass is associated with poor functional status and increased all-cause mortality in cancer. These findings provide clinical evidence of cardiac wasting-associated cardiomyopathy in cancer.PMID:37076211 | DOI:10.1016/j.jacc.2023.02.039
Source: Cancer Control - April 20, 2023 Category: Cancer & Oncology Authors: Alessia Lena Ursula Wilkenshoff Sara Hadzibegovic Jan Porthun Lukas R ösnick Ann-Kathrin Fr öhlich Tanja Zeller Mahir Karakas Ulrich Keller Johann Ahn Lars Bullinger Hanno Riess Stuart D Rosen Alexander R Lyon Thomas F L üscher Matthias Totzeck Tienush Source Type: research

Women's reproductive traits and cerebral small-vessel disease: A two-sample Mendelian randomization study
CONCLUSION: Our findings do not convincingly support a causal effect of women's reproductive factors on CSVD. Future studies are warranted to investigate specific estrogen-related physiological changes in women, which may inform current researchers on the causal mechanisms involved in cerebral small-vessel disease progression.PMID:37064189 | PMC:PMC10098092 | DOI:10.3389/fneur.2023.1064081
Source: Cancer Control - April 17, 2023 Category: Cancer & Oncology Authors: Zhenqian Wang Jiawen Lu Weipin Weng Jie Zhang Source Type: research

Cancers, Vol. 15, Pages 2316: Review of Cardiovascular Risk of Androgen Deprivation Therapy and the Influence of Race in Men with Prostate Cancer
K. Kelly Androgen deprivation therapy is the cornerstone of prostate cancer therapy. Recent studies have revealed an association between androgen deprivation therapy and cardiovascular adverse effects such as myocardial infarction and stroke. This review summarizes the available research on the cardiovascular risk of men using androgen deprivation therapy. We also discuss racial disparities surrounding both prostate cancer and cardiovascular disease, emphasizing the importance of biological/molecular and socioeconomic factors in assessing baseline risk in patients beginning androgen ablation. Based on the literature, ...
Source: Cancers - April 15, 2023 Category: Cancer & Oncology Authors: James Fradin Felix J. Kim Grace L. Lu-Yao Eugene Storozynsky William K. Kelly Tags: Review Source Type: research

The Potential Benefits of Quercetin for Brain Health: A Review of Anti-Inflammatory and Neuroprotective Mechanisms
Int J Mol Sci. 2023 Mar 28;24(7):6328. doi: 10.3390/ijms24076328.ABSTRACTNeuroinflammation is a critical factor in developing and progressing numerous brain diseases, including neurodegenerative diseases. Chronic or excessive neuroinflammation can lead to neurotoxicity, causing brain damage and contributing to the onset and progression of various brain diseases. Therefore, understanding neuroinflammation mechanisms and developing strategies to control them is crucial for treating brain diseases. Studies have shown that neuroinflammation plays a vital role in the progression of neurodegenerative diseases, such as Alzheimer'...
Source: Cancer Control - April 13, 2023 Category: Cancer & Oncology Authors: Ming-Chang Chiang Tsung-Yu Tsai Chieh-Ju Wang Source Type: research

Unknown Causes of Death in Cancer Patients
CONCLUSION: Of the patients, 7.4% died of unknown causes during follow-up and the proportion of death was higher with longer follow-up and among more indolent cancers. The attribution of high percentages of unknown COD to cancer or non-cancer causes could impact population-based cancer registry studies or clinical trial outcomes with respect to measures involving CSS and mortality.PMID:37038261 | DOI:10.1097/COC.0000000000001003
Source: Clinical Prostate Cancer - April 11, 2023 Category: Cancer & Oncology Authors: Siven Chinniah Mckenzee Chiam Kyle Mani Menglu Liang Daniel M Trifiletti Daniel E Spratt Vinayak K Prasad Ming Wang Leila T Tchelebi Nicholas G Zaorsky Source Type: research

Home-Based Buddhist Walking Meditation Mitigates Cardiotoxicity of Anthracycline Chemotherapy in Breast Cancer Patients: A Randomized Controlled Trial
Conclusions: Buddhist walking meditation exercise was effective in mitigating cardiotoxicity of anthracycline chemotherapy on vascular function, aerobic fitness, and quality of life in breast cancer patients. Clinical trial registration number: NCT02676531.PMID:37036793 | DOI:10.1089/jicm.2022.0778
Source: Cancer Control - April 10, 2023 Category: Cancer & Oncology Authors: Saowalak Siripanya Napa Parinyanitikul Hirofumi Tanaka Daroonwan Suksom Source Type: research

Identifying patterns of neurocognitive dysfunction through direct comparison of children with leukemia, central nervous system tumors, and sickle cell disease
CONCLUSIONS: Use of a common metric to quantify the magnitude and type of neurocognitive dysfunction across at-risk groups of participants by disease shows that participants perform below age-expected norms in multiple domains and experience dysfunction differently than one another. This approach highlights patterns of dysfunction that can inform disease- and domain-specific interventions.PMID:37036272 | DOI:10.1002/pbc.30299
Source: Cancer Control - April 10, 2023 Category: Cancer & Oncology Authors: Claire E Fraley Jamie S Neiman Charlotte R Feddersen Claire James Taylor G Jones Margit Mikkelsen Rachelle Nuss Alyssa M Schlenz Amanda C Winters Adam L Green Bruce E Compas Source Type: research