• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Association of cervical atherosclerosis on Doppler ultrasonography and postoperative delirium in patients undergoing spinal surgery: a single-center, retrospective, observational study
ConclusionsThere was a significant association between POD and the prevalence of cervical atherosclerosis using the univariate logistic regression analysis. Furthermore, multivariate logistic regression analyses showed that older age and antiplatelet agent use were independently associated with POD.
Source: European Spine Journal - June 16, 2023 Category: Orthopaedics Source Type: research

Osteoporotic fracture admissions compared to other major medical admissions in Irish public hospitals
ConclusionOsteoporotic fractures represent a large and rapidly increasing illness burden amongst older Irish adults, with substantial care requirements and the resulting onus on our healthcare system. Urgent action is needed to address this public health issue and the services for those at risk of fracture.
Source: Archives of Osteoporosis - December 17, 2022 Category: Orthopaedics Source Type: research

Anemia is associated with increased risk of non-vertebral osteoporotic fractures in elderly men: the MrOS Sweden cohort
ConclusionsAnemia is associated with an increased risk for any fracture and non-vertebral osteoporotic fracture in elderly men with a long follow-up time. The cause is probably multifactorial and our results support that anemia can be used as a predictor for future fracture.
Source: Archives of Orthopaedic and Trauma Surgery - June 23, 2022 Category: Orthopaedics Source Type: research

Weight loss since early adulthood, later life risk of fracture hospitalizations, and bone mineral density: a prospective cohort study of 0.5 million Chinese adults
ConclusionsWeight loss from early adulthood to midlife was associated with a higher risk of hip fracture and lower BMD in later life.
Source: Archives of Orthopaedic and Trauma Surgery - April 18, 2020 Category: Orthopaedics Source Type: research

Effects of Zoledronate on Cancer, Cardiac Events, and Mortality in Osteopenic Older Women
ABSTRACTWe recently showed that zoledronate prevented fractures in older women with osteopenia (hipT‐scores between −1.0 and −2.5). In addition to fewer fractures, this study also suggested that women randomized to zoledronate had fewer vascular events, a lower incidence of cancer, and a trend to lower mortality. The present analysis provides a more detailed presentation of the adverse event data from that study, a 6‐year, double‐blind trial of 2000 women aged>65  years recruited using electoral rolls. They were randomly assigned to receive four infusions of either zoledronate 5 mg or normal saline at 18�...
Source: Journal of Bone and Mineral Research - October 10, 2019 Category: Orthopaedics Authors: Ian R Reid, Anne M Horne, Borislav Mihov, Angela Stewart, Elizabeth Garratt, Sonja Bastin, Gregory D Gamble Tags: Original Article Source Type: research

Co ‐morbidities only account for a small proportion of excess mortality after fracture: a record linkage study of individual fracture types
Conclusion: All proximal non‐hip, non‐vertebral fractures in women and men were associated with increased mortality risk. Co‐existent co‐morbidities independently further increased mortality. Population attributable risk for mortality for fracture was similar to cardiovascular disease and diabetes, highlighting their importance and potential benefit for early intervention and treatment. This article is protected by copyright. All rights reserved
Source: Journal of Bone and Mineral Research - January 4, 2018 Category: Orthopaedics Authors: Weiwen Chen, Judy M. Simpson, Lyn M. March, Fiona M. Blyth, Dana Bliuc, Thach Tran, Tuan V. Nguyen, John A. Eisman, Jacqueline R. Center Tags: Original Article Source Type: research

Incidence And Risk Factors For 30-Day Readmissions After Hip Fracture Surgery.
CONCLUSIONS: The overall rate of readmission following hip fracture surgery was moderate. Surgeons should consider discharge optimization in the at risk cohorts identified here, particularly patients with multiple medical comorbidities or an elevated ASA class, and should focus on wound complications and fall risks in order to minimize readmissions. Further, quality-reporting metrics should account for the risk factors identified here, in order to prevent penalties against surgeons who take on complex patients. PMID: 27528853 [PubMed - in process]
Source: Iowa orthopaedic journal - August 19, 2016 Category: Orthopaedics Tags: Iowa Orthop J Source Type: research

Predictors of 30-day mortality following hip/pelvis fractures
Discussion Several preoperative patient risk factors and postoperative complications greatly increased the odds for patient mortality following 30-days after initial surgery. Orthopaedic surgeons can utilize these predictive risk factors to better improve patient care. Level of evidence Retrospective study. Level IV.
Source: Orthopaedics and Traumatology: Surgery and Research - August 3, 2016 Category: Orthopaedics Source Type: research

Medical morbidities in people following hip and knee arthroplasty: data from the Osteoarthritis Initiative
Conclusions People who undergo THA or TKA may present with a variety of medical morbidities. Accordingly consideration should be made on how to encourage the adoption and maintenance of physical activity and healthy lifestyle choices for this population.
Source: European Journal of Orthopaedic Surgery and Traumatology - October 16, 2015 Category: Orthopaedics Source Type: research

C-reactive protein and fracture risk: European Prospective Investigation into Cancer Norfolk Study
Conclusion: A U-shaped association was observed between CRP and fracture risk. The increased risk of fracture observed at lower end of CRP compared to intermediate levels require further exploration, confirmation in other populations, and investigation into potential biological mechanisms.Highlights:
Source: Bone - July 17, 2013 Category: Orthopaedics Authors: Sara Ahmadi-Abhari, Robert N. Luben, Nicholas J. Wareham, Kay-Tee Khaw Tags: Original Articles Source Type: research