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Total 206 results found since Jan 2013.

Diagnostic accuracy of major stroke types in Chinese adults: A clinical adjudication study involving 40,000 stroke cases
Lancet Reg Health West Pac. 2022 Mar 5;21:100415. doi: 10.1016/j.lanwpc.2022.100415. eCollection 2022 Apr.ABSTRACTBACKGROUND: Widespread use of brain imaging in suspected stroke cases in Chinese adults has prompted the need for clinical adjudication studies of stroke types. We conducted a clinical adjudication study to assess the reporting and diagnostic accuracy of major stroke types.METHODS: The prospective China Kadoorie Biobank recruited >512,000 adults (mean age 52 years, 59% women) from 10 urban and rural areas in China during 2004-2008, and recorded 45,859 first-ever incident stroke cases during an 11-year follow...
Source: Cancer Control - March 14, 2022 Category: Cancer & Oncology Authors: Iain Turnbull Robert Clarke Neil Wright Yu Guo Christina Kartsonaki Pei Pei Alex Hacker Canqing Yu Simon Gilbert Ling Yang Jinyi Zhou Sam Sansome Jun Lv Liming Li Zhengming Chen Yiping Chen Source Type: research

Developing and validating a Chinese multimorbidity-weighted index for middle-aged and older community-dwelling individuals
CONCLUSION: The CMWI is an adequate index to quantify the multimorbidity burden for Chinese middle-aged and older community-dwelling individuals. It can be directly computed via disease status examined in regular community health check-ups to facilitate health management.PMID:35211718 | DOI:10.1093/ageing/afab274
Source: Cancer Control - February 25, 2022 Category: Cancer & Oncology Authors: Wei-Hua Hu Yu-Yang Liu Cong-Hui Yang Tong Zhou Chun Yang Ying-Si Lai Jing Liao Yuan-Tao Hao Source Type: research

Multimorbidity patterns and association with mortality in 0.5 million Chinese adults
CONCLUSION: Cardiometabolic multimorbidity and respiratory multimorbidity posed the highest threat on mortality risk and deserved particular attention in Chinese adults.PMID:35191418 | DOI:10.1097/CM9.0000000000001985
Source: Cancer Control - February 22, 2022 Category: Cancer & Oncology Authors: Junning Fan Zhijia Sun Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Dianjianyi Sun Yuanjie Pang Jun Zhang Simon Gilbert Daniel Avery Junshi Chen Zhengming Chen Jun Lyu Liming Li China Kadoorie Biobank Collaborative Group Source Type: research

The impact of COVID-19 on the comorbidities: A review of recent updates for combating it
Saudi J Biol Sci. 2022 Feb 10. doi: 10.1016/j.sjbs.2022.02.006. Online ahead of print.ABSTRACTCoronavirus disease is caused by the SARS-CoV-2. The virus first appeared in Wuhan (China) in December 2019 and has spread globally. Till now, it affected 26.9 Crore peoples and 53 Lakh deaths in 224 countries and territories. With the emergence of variants like Omicron, the COVID-19 cases grew exponentially, with thousands of deaths. The general symptoms of COVID-19 include fever, sore throat, cough, lung infections, and, in severe cases, acute respiratory distress syndrome, sepsis, and death. SARS-CoV-2 predominantly affects the...
Source: Cancer Control - February 15, 2022 Category: Cancer & Oncology Authors: Jonaid Ahmad Malik Sakeel Ahmed Mrunal Shinde Mohammed Hajjaj Saeid Al-Marmash Saleh Alghamdi Arshad Hussain Sirajudheen Anwar Source Type: research

What drives long-term PM < sub > 2.5 < /sub > -attributable premature mortality change? A case study in central China using high-resolution satellite data from 2003 to 2018
Environ Int. 2022 Feb 5;161:107110. doi: 10.1016/j.envint.2022.107110. Online ahead of print.ABSTRACTAmbient PM2.5 was reported to be related to numerous negative health outcomes, leading to adverse public health impacts in many countries such as China. Despite the apparent reduction in PM2.5 levels over China due to its emission control policies in recent years, the health burdens were not reduced as much as expected. This calls for a comprehensive analysis to explain the reasons behind to provide a useful reference for formulating effective emission control strategies. Taking central China as an example due to its large ...
Source: Environment International - February 8, 2022 Category: Environmental Health Authors: Qingqing He Yefu Gu Steve Hung Lam Yim Source Type: research

Knockdown of NAA25 Suppresses Breast Cancer Progression by Regulating Apoptosis and Cell Cycle
Front Oncol. 2022 Jan 13;11:755267. doi: 10.3389/fonc.2021.755267. eCollection 2021.ABSTRACTNAA25 gene variants were reported as risk factors for type 1 diabetes, rheumatoid arthritis and acute arterial stroke. But it's unknown whether it could contribute to breast cancer. We identified rs11066150 in lncHSAT164, which contributes to breast cancer, in our earlier genome-wide long non-coding RNA association study on Han Chinese women. However, rs11066150 A/G variant is also located in NAA25 intron. Based on the public database, such as TCGA and Curtis dataset, NAA25 gene is highly expressed in breast cancer tissues and this ...
Source: Cancer Control - January 31, 2022 Category: Cancer & Oncology Authors: Jingkai Xu Zhi Li Xianbo Zuo Guozheng Li Xuejun Zhang Bo Zhang Yong Cui Source Type: research

Healthcare resource utilisation for chronic kidney disease and other major non-communicable chronic diseases in China: a cross-sectional study
Conclusions The presence of diagnosed CKD alongside each major NCD was associated with an additional burden on the healthcare system. Healthcare resource utilisation and prognosis of CKD were comparable with those of other major NCDs, which highlights the importance of CKD as a major public health burden.
Source: BMJ Open - January 13, 2022 Category: General Medicine Authors: Yang, C., Long, J., Shi, Y., Zhou, Z., Wang, J., Zhao, M.-H., Wang, H., Zhang, L., Coresh, J. Tags: Open access, Epidemiology Source Type: research

Tai Chi for anxiety and depression symptoms in cancer, stroke, heart failure, and chronic obstructive pulmonary disease: A systematic review and meta-analysis
CONCLUSION: Tai Chi has a positive effect on anxiety and depression, especially for patients with cancer, stroke, and HF. However, given the weak evidence, this approach is not a substitute for psychiatric treatment.PMID:34749040 | DOI:10.1016/j.ctcp.2021.101510
Source: Complementary Therapies in Clinical Practice - November 8, 2021 Category: Complementary Medicine Authors: Qian Cai Shu-Bin Cai Jian-Kun Chen Xiao-Hui Bai Chun-Xiang Jing Xi Zhang Ji-Qiang Li Source Type: research

Janssen to Present the Strength and Promise of its Hematologic Malignancies Portfolio and Pipeline at ASH 2021
RARITAN, N.J., November 4, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today that more than 45 company-sponsored abstracts, including 11 oral presentations, plus more than 35 investigator-initiated studies will be featured at the American Society of Hematology (ASH) Annual Meeting and Exposition. ASH is taking place at the Georgia World Congress Center in Atlanta and virtually from December 11-14, 2021.“We are committed to advancing the science and treatment of hematologic malignancies and look forward to presenting the latest research from our robust portfolio and pipeline during ASH...
Source: Johnson and Johnson - November 5, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Zuogui Pill Attenuates Neuroinflammation and Improves Cognitive Function in Cerebral Ischemia Reperfusion-Injured Rats
Conclusion: This study provided protective roles of ZGP on cell viability and apoptosis induced by OGD/R. In addition, ZGP played protective roles on neuroinflammation and cognitive function in rats.Neuroimmunomodulation
Source: Neuroimmunomodulation - November 4, 2021 Category: Allergy & Immunology Source Type: research

Association of total cholesterol and atherosclerotic cardiovascular disease in patients with follicular thyroid cancer: A real-world study from Chinese populations
The association between serum total cholesterol (TC) level and incident atherosclerotic cardiovascular disease (ASCVD) in patients with follicular thyroid cancer postthyroidectomy is unknown. This was a retrospective study and patients (n = 384) were divided into low and high TC groups according to the median TC level. Incidence of composite ASCVD (myocardial infarction, ischemic stroke, and cardiovascular death) was compared between these 2 groups and factors contributing to the association of TC and ASCVD were evaluated. Patients in the high TC group were older and more likely to have diabetes and have higher C...
Source: Medicine - October 1, 2021 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research

Pure Thalamic Infarct: 8-Year Follow-Up Study in a Hospital in China
In conclusion, our cohort of pure thalamic infarcts were mainly due to SVO (TOAST), with hypertension as the main risk factor, and the inferolateral artery as the most implicated arterial territory. Less severe outcome or stroke recurrence are identified in long-term follow-up of pure thalamic infarcts. Other comorbidities would be cause of death in aged patients.
Source: Frontiers in Neurology - September 14, 2021 Category: Neurology Source Type: research