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Total 872 results found since Jan 2013.
Comparison of Doctors' and Breast Cancer Patients' Perceptions of Docetaxel, Epirubicin, and Cyclophosphamide (TEC) Toxicity
Abstract
In Spain, around 26,000 cases of breast cancer are diagnosed each year, representing nearly 30% of all cancers in women. The aim this study was to compare the perceptions of nonhematologic toxicities after administration of a docetaxel, epirubicin, and cyclophosphamide (TEC) regimen between breast cancer patients and oncologists. Furthermore, the relationship between such adverse events and quality of life (QOL) was evaluated. Cross‐sectional study carried out among 92 breast cancer patients who received TEC as neoadjuvant or adjuvant treatment. The main nonhematologic toxicities experienced by breast cancer pat...
Source: The Breast Journal - February 11, 2016 Category: Cancer & Oncology Authors: Juan Bayo, Blanca Prieto, Francisco Rivera Tags: Original Article Source Type: research
Newsweek's One-Sided Valentine to the Anti-GMO Movement
Anatomy of a Newsweek Valentine to the Anti-GMO Movement Imagine a press call like this: Giant Oil Company Executive: We are here to talk to a scientist who has authored a new study called: "Huffing Oil Prevents Cancer" Scientist: I estimate that those who have huffed oil every day for 22 years will never get cancer. Based on my study, all people should buy more oil and huff it daily. Reporter: That is a great headline. I will write this story in 4 hours. Giant Oil Company Executive: Here is a list of references and links. Scientist: I am a scientist. You do not need to verify or fact-check. Reporter: I love oil! I will ...
Source: Science - The Huffington Post - February 10, 2016 Category: Science Source Type: news
Extrahepatic metabolism at the body's internal-external interfaces.
Authors: Gundert-Remy U, Bernauer U, Blömeke B, Döring B, Fabian E, Goebel C, Hessel S, Jäckh C, Lampen A, Oesch F, Petzinger E, Völkel W, Roos PH
Abstract
In general, xenobiotic metabolizing enzymes (XMEs) are expressed in lower levels in the extrahepatic tissues than in the liver, making the former less relevant for the clearance of xenobiotics. Local metabolism, however, may lead to tissue-specific adverse responses, e.g. organ toxicities, allergies or cancer. This review summarizes the knowledge on the expression of phase I and phase II XMEs and transporters in extrahepatic tissues at the body's internal-ex...
Source: Drug Metabolism Reviews - February 16, 2016 Category: Drugs & Pharmacology Tags: Drug Metab Rev Source Type: research
4 Surprising Everyday Items That Can Hurt Your Health
SPECIAL FROM You may watch what you eat, drink filtered water, and use your seat belt to protect yourself on the road. Yet many health hazards are lurking around us in not-so-obvious places. Here, a few to steer clear of: 1. Scented candles A fragrant candle may help you unwind and de-stress. But burning those containing a chemical calledlimonene, often used for citrus-scented candles, as well as many cleaning products, can produce fumes that are downright unhealthy. Recent British research found that households with a high levels of limonene correlated with high levels of formaldehyde, which irritates the eyes and ...
Source: Healthy Living - The Huffington Post - February 20, 2016 Category: Consumer Health News Source Type: news
How Living With Someone Makes Your Immune Systems Eerily Similar
When you live with someone, it turns out that it can be way more intimate than just sharing space -- you can also end up having similar immune systems. A new study, published in the journal Nature Immunology last week, suggests that the cellular composition of our immune systems is partly shaped by who we live with as well as our age. The research marks the first time that the immune systems of two unrelated individuals in a close relationship have been closely analyzed and compared, said Dr. Adrian Liston, a researcher at the Flanders Institute for Biotechnology in Belgium and a co-author of the study. "We alrea...
Source: Science - The Huffington Post - February 26, 2016 Category: Science Source Type: news
The Role of Store-operated Calcium Channels in Pain.
Abstract
Store-operated calcium channels (SOCCs) are calcium-selective cation channels. Recently, there has been explosive growth in establishing the molecular mechanisms that mediate store-operated Ca(2+) entry (SOCE) and the role of this process in normal cellular function and disease states. SOCCs and its components appear to play an important role in many Ca(2+)-dependent processes in nonexcitable cells and are implicated in several possible disorders including allergies, multiple sclerosis, cancer, and inflammatory bowel disease. Recent studies have shown that SOCCs are expressed in the central nervous system...
Source: Advances in Pharmacology - February 29, 2016 Category: Drugs & Pharmacology Authors: Munoz F, Hu H Tags: Adv Pharmacol Source Type: research
Abstract P2-12-02: Axillary reverse mapping: A feasibility study
ConclusionThe identification rate of ARM lymphatics and nodes is low when only blue dye is used. The method appears it to be oncologically safe in patients with low tumour burden. However there is need for further studies will before this procedure can be universally applied without compromising the oncologic safety.Once the technique is proven to be oncologically safe even in a selected group of patients, a large randomized trial will be needed to give a satisfactory answer whether the problem of lymphedema be eliminated or minimized in the patients in whom arm lymphatics are successfully preserved.Citation Format: Khare ...
Source: Cancer Research - February 18, 2016 Category: Cancer & Oncology Authors: Khare, S., Singh, G., Das, A., Bal, A. Tags: Poster Session Abstracts Source Type: research
Can a trigger-happy immune system cause cancer after viral infection? | Cath Ennis
Friendly fire: while the immune system tries to protect us from viruses, it could be causing cancerThe immune system is a fickle thing, both hero and villain. The ability of our ancestors to survive plague and pestilence was one of the forces that shaped the evolution of the human species into its current form. But many of us now find ourselves in environments where many of the biggest infectious threats have been neutralised by a combination of vaccination programmes, improved hygiene, and (temporarily) effective treatments. With their usual duties cut back so drastically, our evolutionary superstar immune systems sometim...
Source: Guardian Unlimited Science - June 6, 2014 Category: Science Authors: Cath Ennis Tags: Science Vaccines and immunisation Cancer Immunology Medical research Health Biochemistry and molecular biology Source Type: news
Paricalcitol attenuates lipopolysaccharide-induced myocardial inflammation by regulating the NF-κB signaling pathway.
Abstract
Vitamin D deficiency is associated with an increased risk of cardiovascular disease, diabetes, colon and breast cancer, infectious diseases and allergies. Vascular alterations are an important pathophysiological mechanism of sepsis. Experimental data suggest that paricalcitol, a vitamin D2 analogue, exerts beneficial effects on renal inflammation and fibrosis. In the present study, we aimed to investigate the effects of paricalcitol on lipopolysaccharide (LPS)-induced myocardial inflammation and to elucidate the underlying mechanisms. We used primary cultured human umbilical vein endothelial cells for...
Source: International Journal of Molecular Medicine - March 4, 2016 Category: Molecular Biology Authors: Lee AS, Jung YJ, Thanh TN, Lee S, Kim W, Kang KP, Park SK Tags: Int J Mol Med Source Type: research
From immunotoxicity to carcinogenicity: the effects of carbamate pesticides on the immune system.
Abstract
The immune system can be the target of many chemicals, with potentially severe adverse effects on the host's health. In the literature, carbamate (CM) pesticides have been implicated in the increasing prevalence of diseases associated with alterations of the immune response, such as hypersensitivity reactions, some autoimmune diseases and cancers. CMs may initiate, facilitate, or exacerbate pathological immune processes, resulting in immunotoxicity by induction of mutations in genes coding for immunoregulatory factors and modifying immune tolerance. In the present study, direct immunotoxicity, endocrine d...
Source: Environmental Science and Pollution Research International - March 18, 2016 Category: Environmental Health Authors: Dhouib I, Jallouli M, Annabi A, Marzouki S, Gharbi N, Elfazaa S, Lasram MM Tags: Environ Sci Pollut Res Int Source Type: research
Father of Boy Forced to Leave Plane Due to Allergies Dies of Cancer
Jorge Alvarado died from esophageal cancer at age 48.
Source: ABC News: Health - March 25, 2016 Category: Consumer Health News Tags: Health Source Type: news
Nutrient for Tinnitus Treatment
If you’re suffering from tinnitus, I’m pretty sure doctors and ENT specialists have told you something like: “I’m afraid you’re just going to have to live with it” or “It’s just age-related hearing loss.”
What is tinnitus?
Tinnitus, the constant ringing, thundering, whooshing or whistling in the ears, is aggravating and nerve-racking. It robs you of sleep. It shatters your focus and concentration. And it drowns out your hearing, because of all the background noise in your head.
Tinnitus is not a disease, but rather a symptom of some other underlying health condition.
Ma...
Source: Al Sears, MD Natural Remedies - April 1, 2016 Category: Complementary Medicine Authors: Al Sears Tags: Health Source Type: news
FDA warns parents about arsenic in rice cereal
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For years, rice cereal has been a go-to for parents when they start their babies on solid foods.
It’s time to change that.
In 2012, the Consumer Products Safety Commission (CPSC) issued a report warning about high levels of inorganic arsenic in rice and rice products. Rice plants are particularly good at absorbing arsenic from the soil, in particular because they grow in a lot of water. Inorganic arsenic is a common ingredient in pesticides and other products used in farming, and can linger in the soil for a long time after it is used. It can be poisonous. In high doses it is lethal, but even small...
Source: New Harvard Health Information - April 5, 2016 Category: Consumer Health News Authors: Claire McCarthy, MD Tags: Children's Health Parenting Safety Source Type: news
Lost at Sea in Search of a Diagnosis: A Case of Unexplained Bleeding
Scurvy results from a dietary deficiency of vitamin C (ascorbic acid) and is rarely thought of in modern day medicine. It now almost always occurs in pediatric patients with behavioral diagnoses, nutritionally restricted diets, and food allergies. Symptoms of scurvy include ecchymoses, bleeding gums, and arthralgias. Here, we present a 17‐year‐old male with autism spectrum disorder and a diet severely deficient in ascorbic acid due to textural aversion and food preferences. He presented with recurrent arthritis, hemarthrosis, bruising, and anemia. His vitamin C level was low, and his symptoms improved promptly after tr...
Source: Pediatric Blood and Cancer - April 8, 2016 Category: Cancer & Oncology Authors: Lauren E. Amos, Shannon L. Carpenter, Mark F. Hoeltzel Tags: BRIEF REPORT Source Type: research
