Filtered By:
Condition: Diabetes
Cancer: Myeloma

This page shows you your search results in order of relevance.

Order by Relevance | Date

Total 14 results found since Jan 2013.

A Year in Review: FDA 2015 New Drug Approvals
The approval of first-of-a-kind drugs rose last year to forty-one, resulting in the highest level of newly approved U.S. drugs in nineteen years. The total number of new drugs approved last year was even higher at sixty-nine. The rising figures reflect an industry-wide desire to research and develop drugs for rare and hard-to-treat diseases. The newly approved drugs serve to advance medical care and the health of patients suffering from many ailments, including various forms of cancer, heart failure, and cystic fibrosis. Additionally, more than 40% of the new therapies were approved for treatment of rare or "orphan" dise...
Source: Policy and Medicine - January 13, 2016 Category: American Health Authors: Thomas Sullivan - Policy & Medicine Writing Staff Source Type: blogs

Precision Medicine and the Reinvention of Human Disease (Book Index)
In January, 2018, Academic Press published my bookPrecision Medicine and the Reinvention of Human Disease. This book has an excellent " look inside " at itsGoogle book site, which includes the Table of Contents. In addition, I thought it might be helpful to see the topics listed in the Book ' s index. Note that page numbers followed by f indicate figures, t indicate tables, and ge indicate glossary terms.AAbandonware, 270, 310geAb initio, 34, 48ge, 108geABL (abelson leukemia) gene, 28, 58ge, 95 –97Absidia corymbifera, 218Acanthameoba, 213Acanthosis nigricans, 144geAchondroplasia, 74, 143ge, 354geAcne, 54ge, 198, 220geAcq...
Source: Specified Life - January 23, 2018 Category: Information Technology Tags: index jules berman jules j berman precision medicine Source Type: blogs

Measuring What Matters In Primary Care
Editor’s Note: This is one of several posts Health Affairs Blog is publishing stemming from sessions at the June 2015 AcademyHealth Annual Research Meeting (ARM) in Minneapolis. What Do We Mean By ‘Primary Care’ Numerous studies have confirmed the central role of excellent primary care to any health system. Yet how to define the presence of excellent primary care remains a challenge. A recent review found that five characteristics remain the “sine qua non” for primary care practice: Accessible (first contact) care Continuous care Comprehensive care Coordinated care Accountable/whole-person care. Each individual...
Source: Health Affairs Blog - October 6, 2015 Category: Health Management Authors: Eugene Rich and Ann O’Malley Tags: Costs and Spending Featured Health Professionals Hospitals Medicare Organization and Delivery Population Health Quality AcademyHealth 2015 ARM Access chronic conditions clinician productivity comprehensive care continuous care Source Type: blogs

The Art of Medicine: Taking a Military History
This article was prepared by the authors above in his/her personal capacity. The opinions expressed in this article are the author’s own and do not reflect the view of the Department of Veterans Affairs, VA Connecticut Healthcare System or the United States government. Title: The Forgotten Question: Taking a Military History Authors: Meredith Bertrand, NP1 Eugenia Betz, MD1,2 Alice Grant, NP1 Leila Haghighat, MD1,2 Janet Ku, NP1 Sumit R. Kumar, MD1,2 Mona Lalehzari, MD1,2 Benjamin Y. Lu, MD1,2 J. Nicholas Pumilia, MD1,2 Jonathan Stock, MD1,2 Anna Reisman, MD1,2,3 1.     VA Centers of Excellence in Primary Care Ed...
Source: The Health Care Blog - April 15, 2018 Category: Consumer Health News Authors: John Irvine Tags: Uncategorized Source Type: blogs

Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

“ Use of curcumin in multiple myeloma patients intolerant of steroid therapy ”
Conclusion”). The other 12 patients, however, are stable and doing well, in spite of the fact that some have high-risk cytogenetic and FISH abnormalities. The combination of curcumin and the other conventional drugs reduced their paraprotein levels by 38%, and plasmacytosis by 59%. How about that? Anyway, it’s not a difficult read, methinks, so please have a look at the above link… Thank you, Dr. Golombick! I am so grateful to you and your team for all your tireless work. You give us hope!!! :-) Thank You Thank You Thank You!!! We need MORE studies like this one! Not 10 years from now…but…NOW!!!!!!!!!! 
Source: Margaret's Corner - February 28, 2020 Category: Cancer & Oncology Authors: Margaret Tags: Blogroll curcumin Golombick myeloma Source Type: blogs

Fight Aging! Newsletter, January 2nd 2023
In conclusion, circulating monocytes in older adults exhibit increased expression of activation, adhesion, and migration markers, but decreased expression of co-inhibitory molecules. MERTK Inhibition Increases Bone Density via Increased Osteoblast Activity https://www.fightaging.org/archives/2022/12/mertk-inhibition-increases-bone-density-via-increased-osteoblast-activity/ Bone density results from the balance of constant activity on the part of osteoblasts and osteoclasts, the former building bone, the latter breaking it down. With advancing age, the balance of activity shifts to favor osteoclasts, prod...
Source: Fight Aging! - January 1, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, October 7th 2019
In conclusion, our findings link the calcification of the vascular tissue with the expression of FGF23 in the vessels and with the elevation of circulating levels this hormone. Permanently Boosting Levels of Natural Killer Cells in Mice to Increase Cancer Resistance https://www.fightaging.org/archives/2019/09/permanently-boosting-levels-of-natural-killer-cells-in-mice-to-increase-cancer-resistance/ Researchers here demonstrate a very interesting approach to immunotherapy: they introduce engineered stem cells in mice that will give rise to additional natural killer T cells, boosting the capability of the ...
Source: Fight Aging! - October 6, 2019 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

How Patient Groups Have Begun To Influence The Value And Coverage Debate
In 2015, two issues related to medicine could be relied on to generate headlines: drug pricing and the proliferation of new value frameworks that claimed to define the value and even the price of drugs in seemingly easy-to-understand ways. In none of the high-profile skirmishes on pricing or frameworks was the voice or perspective of patients and patient groups very much in evidence. But that is beginning to change, in an evolution of a broader shift in the role that patients are playing in the research and development (R&D) enterprise. A New Culture of Engagement Patients and patient organizations are becoming ever mo...
Source: Health Affairs Blog - June 10, 2016 Category: Health Management Authors: Margaret Anderson and Kristin Schneeman Tags: Costs and Spending Health Professionals Organization and Delivery Quality clinical research patient use of evidence venture philanthropy Source Type: blogs

Fight Aging! Newsletter, March 15th 2021
In conclusion, PLG attenuates high calcium/phosphate-induced vascular calcification by upregulating P53/PTEN signaling in VSMCs. Tsimane and Moseten Hunter-Gatherers Exhibit Minimal Levels of Atrial Fibrillation https://www.fightaging.org/archives/2021/03/tsimane-and-moseten-hunter-gatherers-exhibit-minimal-levels-of-atrial-fibrillation/ Epidemiological data for the Tsimane and Moseten populations in Bolivia shows that they suffer very little cardiovascular disease in later life, despite a presumably greater lifetime burden of infectious disease (and consequent inflammation) than is the case for people i...
Source: Fight Aging! - March 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, August 23rd 2021
In this study, we used the UK Biobank (n = 440,185) to resolve previous ambiguities in the relationship between serum IGF-1 levels and clinical disease. We examined prospective associations of serum IGF-1 with mortality, dementia, vascular disease, diabetes, osteoporosis, and cancer, finding two generalized patterns. First, IGF-1 interacts with age to modify risk in a manner consistent with antagonistic pleiotropy; younger individuals with high IGF-1 are protected from disease, while older individuals with high IGF-1 are at increased risk for incident disease or death. Second, the association between IGF-1 and risk ...
Source: Fight Aging! - August 22, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Top stories in health and medicine, December 13, 2013
From MedPage Today: Tx, Transplant Predict Multiple Myeloma Survival. Only about one multiple myeloma patient in 13 will live more than 10 years. Psychiatrists Top Cash-Only MD List. Nearly 45% of psychiatrists refuse private insurance or Medicare payments for services, and more than half do not take Medicaid — vastly higher percentages than in other specialties. Mobile Apps Can Save Billions in Health Costs. If Omri Bob Shor’s father doesn’t take his diabetes medication or accidentally takes too much insulin, Shor gets an alert to his phone telling him so. 3 Meds Better Than 2 for Older Myeloma Patient...
Source: Kevin, M.D. - Medical Weblog - December 13, 2013 Category: Family Physicians Tags: News Cancer Mobile health Psychiatry Source Type: blogs

Top stories in health and medicine, June 24, 2014
From MedPage Today: Mrs. Obama’s Lunch Plan: Not So Fast. In the guest blog post, Steven Horvitz, DO, a primary care physician in Moorestown, N.J., responds to MedPage Today’s coverage of the Michelle Obama-led White House roundtable criticizing Congressional efforts to reverse nutrition requirements in public schools. More Than 750 Hospitals Face Patient Injury Crackdown. During a hernia operation, Dorothea Handron’s surgeon unknowingly pierced her bowel. It took 5 days for doctors to determine she had an infection. By the time they operated on her again, she was so weakened that she was placed in a me...
Source: Kevin, M.D. - Medical Weblog - June 24, 2014 Category: Journals (General) Authors: Tags: News Diabetes Endocrinology Hospital Obesity Source Type: blogs

Diagnosis – the adjectives are just as important as the nouns
This article from the Clinical Journal of the American Society of Nephrology speaks loudly to this problem – The CKD Classification System in the Precision Medicine Era Chronic diseases of the kidney range from rare inherited disorders, such as Fabry disease, to more common acquired entities, such as diabetic kidney disease. Despite the myriad clinical phenotypes and histopathologic subtypes, even within, for example, diabetic kidney disease, this diverse collective is viewed similarly when estimates of glomerular filtration align. Contrast this approach with that of multiple myeloma, a diagnosis that prompts routine...
Source: DB's Medical Rants - December 6, 2016 Category: Internal Medicine Authors: rcentor Tags: Medical Rants Source Type: blogs