The Art of Medicine: Taking a Military History
This article was prepared by the authors above in his/her personal capacity. The opinions expressed in this article are the author’s own and do not reflect the view of the Department of Veterans Affairs, VA Connecticut Healthcare System or the United States government. Title: The Forgotten Question: Taking a Military History Authors: Meredith Bertrand, NP1 Eugenia Betz, MD1,2 Alice Grant, NP1 Leila Haghighat, MD1,2 Janet Ku, NP1 Sumit R. Kumar, MD1,2 Mona Lalehzari, MD1,2 Benjamin Y. Lu, MD1,2 J. Nicholas Pumilia, MD1,2 Jonathan Stock, MD1,2 Anna Reisman, MD1,2,3 1. VA Centers of Excellence in Primary Care Education, West Haven Veterans Affairs Hospital, West Haven, CT 2. Department of Internal Medicine, Yale School of Medicine, New Haven, CT 3. Program for Humanities in Medicine, Yale School of Medicine, New Haven, CT.
Conclusion: DV may be a useful biomarker for early prediction of therapeutic outcome in intermediate HCC. Published on 2018-04-20 13:58:11
Current diabetes screening criteria miss half of patients with diabetes and prediabetes; using an expanded version could identify many more high-risk individuals.Medscape Medical News
Experts say more screening is needed to tackle the disease, which affects pregnant women.
"We all know certain dogs enjoy chewing things they shouldn't but managing to devour four full teddy bears is quite a feat," the dog's vet said
AbstractThe geriatric nutritional risk index (GNRI) is a simple and well-established nutritional assessment tool that is a significant prognostic factor for various cancers. However, the role of the GNRI in predicting clinical outcomes of diffuse large B cell lymphoma (DLBCL) patients has not been investigated. To address this issue, we retrospectively analyzed a total of 476 patients with newly diagnosed de novo DLBCL. We defined the best cutoff value of the GNRI as 96.8 using a receiver operating characteristic curve. Patients with a GNRI
AbstractRecent reports identify NLR (the ratio between absolute neutrophils counts, ANC, and absolute lymphocyte count, ALC), as predictor of progression-free survival (PFS) and overall survival (OS) in cancer patients. We retrospectively tested NLR and LMR (the ratio between absolute lymphocyte and monocyte counts) in newly diagnosed Hodgkin lymphoma (HL) patients treated upfront with a PET-2 risk-adapted strategy. NLR and LMR were calculated using records obtained from the complete blood count (CBC) from 180 newly diagnosed HL patients. PFS was evaluated accordingly to Kaplan-Meier method. Higher NLR was associated to ad...
AbstractThe effect of immunomodulatory drugs (IMiDs) on serious infection remains uncertain. We therefore conducted a systematic review and meta-analysis to assess the possible impact of IMiDs on serious infection in patients with multiple myeloma (MM). We searched randomized controlled trials (RCTs) and observational studies from databases that addressed the effect of IMiDs on serious infection in patients with MM. We pooled data from RCTs and observational studies separately and used the GRADE approach to rate the quality of evidence. Rates in patients with individual IMiDs at different treatment status ranged from 7.00 ...
CONCLUSIONS: D-FP21-PEG-PEI/plasmid DNA is a safe and efficient gene delivery vehicle for ovarian cancer targeted therapy. PMID: 29667478 [PubMed - in process]
Authors: Rafael D, Gener P, Andrade F, Seras-Franzoso J, Montero S, Fernández Y, Hidalgo M, Arango D, Sayós J, Florindo HF, Abasolo I, Schwartz S, Videira M Abstract Development of RNA interference-based therapies with appropriate therapeutic window remains a challenge for advanced cancers. Because cancer stem cells (CSC) are responsible of sustaining the metastatic spread of the disease to distal organs and the progressive gain of resistance of advanced cancers, new anticancer therapies should be validated specifically for this subpopulation of cells. A new amphihilic-based gene delivery system that ...
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