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Specialty: Infectious Diseases
Infectious Disease: Influenza
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Total 578 results found since Jan 2013.
Safety and Immunogenicity of the BNT162b2 Vaccine Coadministered with Seasonal Inactivated Influenza Vaccine in Adults
ConclusionsBNT162b2 coadministered with SIIV elicited immune responses that were noninferior to those elicited by BNT162b2 alone and SIIV alone, and BNT162b2 had an acceptable safety profile when coadministered with SIIV. The results of this study support the coadministration of BNT162b2 and SIIV in adults.Trial RegistrationClinicalTrials.gov registration: NCT05310084.
Source: Infectious Diseases and Therapy - September 12, 2023 Category: Infectious Diseases Source Type: research
Nasal mucosal IgA levels against SARS-CoV-2 and seasonal coronaviruses are low in children but boosted by reinfection
Repeated coronavirus infections in childhood drive progressive maturation of systemic immune responses into adulthood. Analyses of immune responses in children have focused primarily upon systemic assessment but the importance of mucosal immunity is increasingly recognised. We studied virus-specific antibody responses in contemporaneous nasal swab and blood samples from 99 children (4-15 years) and 28 adults (22-56 years), all of whom had prior SARS-CoV-2 infection. Whilst mucosal IgA titres against Influenza and Respiratory Syncytial virus were comparable between children and adults, those against all coronaviruses, inclu...
Source: Journal of Infection - September 1, 2023 Category: Infectious Diseases Authors: Alexander C. Dowell, Gokhan Tut, Jusnara Begum, Rachel Bruton, Christopher Bentley, Megan Butler, Grace Uwenedi, Jianmin Zuo, Annabel A. Powell, Andrew J. Brent, Bernadette Brent, Frances Baawuah, Ifeanyichukwu Okike, Joanne Beckmann, Shazaad Ahmad, Felic Source Type: research
Arbidol: The current demand, strategies, and antiviral mechanisms
CONCLUSION: ARB is a broad-spectrum antiviral drug that inhibits several viruses in vivo and in vitro, with high safety profile and low resistance; the antiviral mechanisms of ARB deserve to be further explored and more high-quality clinical studies are required to establish the efficacy and safety of ARB.PMID:37647451 | DOI:10.1002/iid3.984
Source: Herpes - August 30, 2023 Category: Infectious Diseases Authors: Yue Kang Yin Shi Silu Xu Source Type: research
Prevalence and associated outcomes of co-infection between SARS-CoV-2 and influenza: a systematic review and meta-analysis
Since the first case of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection was reported in late 2019, the ensuing coronavirus disease 2019 (COVID-19) pandemic has spread rapidly across the globe, causing an unprecedented health burden in many countries. As of June 7, 2023, the COVID-19 pandemic has caused 767.7 million infections and 6.9 million deaths worldwide [1]. Although the World Health Organization declared the end of the pandemic emergency on May 5, 2023 [2], endemics remain possible as the virus continues to undergo genetic mutations [3].
Source: International Journal of Infectious Diseases - August 28, 2023 Category: Infectious Diseases Authors: Xiaolong Yan, Ke Li, Zhiqun Lei, Jiayao Luo, Qi Wang, Sheng Wei Source Type: research
Exploring missed opportunities for influenza vaccination and influenza vaccine co-administration patterns among Italian older adults: a retrospective cohort study
CONCLUSIONS: A sizeable proportion of older adults who received other recommended vaccines during the last influenza season did not receive SIV. This share of missed opportunities, which are subject to some social inequalities, may be addressed by increasing vaccine co-administration rates and implementing tailored health promotion interventions.PMID:37632235 | DOI:10.1093/eurpub/ckad155
Source: Herpes - August 26, 2023 Category: Infectious Diseases Authors: Alexander Domnich Andrea Orsi Matilde Ogliastro Carlo-Simone Trombetta Marianna Scarpaleggia Chiara Ceccaroli Carla Amadio Anna Raffo Luca Berisso Alla Yakubovich Giacomo Zappa Daniela Amicizia Donatella Panatto Giancarlo Icardi Source Type: research
Vaccine-induced and hybrid immunity to SARS-CoV-2 after three or four doses of BNT162b2 - results from 22 months follow-up of a healthcare workers cohort, Israel, 2020-2022
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has killed at least seven million worldwide since its emergence in China in late 2019 [1] and became the most significant global health crisis since the 1918 influenza pandemic [2]. In order to mitigate the spread of the pandemic, non-pharmaceutical interventions such as protective equipment and social distancing as well as the rapid development and mass implementation COVID-19 vaccines, have been rolled out to prevent death, reduce the spread and severity of disease, and protect healthcare systems from becoming overwhelmed [2].
Source: International Journal of Infectious Diseases - August 10, 2023 Category: Infectious Diseases Authors: Michael Edelstein, Karine Wiegler Beiruti, Hila Ben-Amram, Netta Beer, Christian Sussan, Perachel Batya, Salman Zarka, Kamal Abu Jabal Source Type: research
Paradigm shift of respiratory viruses causing lower respiratory tract infection in children during COVID-19 pandemic in India
Conclusions: The COVID-19 pandemic significantly impacted the frequency and pattern of respiratory viruses among hospitalized children with ALRTIs in India.
Source: The Journal of Infection in Developing Countries - July 26, 2023 Category: Infectious Diseases Authors: Mannat Kang, Subhabrata Sarkar, Suresh Kumar Angurana, Pankaj Singh, Meenakshi Rana, Ishani Bora, Rishi Chetanya, Bharatendu Singh, Jayashree Muralidharan, Radha Kanta Ratho Source Type: research
Lack of neutralizing antibodies against influenza A viruses in adults during the 2022/2023 winter season – a serological study using retrospective samples collected in Hong Kong
Hong Kong adopted long and stringent non-pharmaceutical interventions during the period of the coronavirus disease (COVID-19) pandemic. A significantly decreased activity of influenza A viruses was also observed since 2020 as recorded by the weekly influenza surveillance (https://www.chp.gov.hk/en/resources/29/304.html), especially after the social distancing and mandatory mask-wearing regulation came into effect [1]. It is expected that influenza virus outbreak will re-emerge after easing of these restrictions in post COVID-19 era.
Source: International Journal of Infectious Diseases - July 20, 2023 Category: Infectious Diseases Authors: Weiwen Liang, Huibin Lv, Chunke Chen, Yuanxin Sun, David S Hui, Chris Ka Pun Mok Tags: Short Communication Source Type: research
Picolinic acid is a broad-spectrum inhibitor of enveloped virus entry that restricts SARS-CoV-2 and influenza A virus in vivo
Cell Rep Med. 2023 Jul 13:101127. doi: 10.1016/j.xcrm.2023.101127. Online ahead of print.ABSTRACTThe COVID-19 pandemic highlights an urgent need for effective antivirals. Targeting host processes co-opted by viruses is an attractive antiviral strategy with a high resistance barrier. Picolinic acid (PA) is a tryptophan metabolite endogenously produced in mammals. Here, we report the broad-spectrum antiviral activity of PA against enveloped viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), influenza A virus (IAV), flaviviruses, herpes simplex virus, and parainfluenza virus. Mechanistic studies ...
Source: Herpes - July 18, 2023 Category: Infectious Diseases Authors: Rohan Narayan Mansi Sharma Rajesh Yadav Abhijith Biji Oyahida Khatun Sumandeep Kaur Aditi Kanojia Christy Margrat Joy Raju Rajmani Pallavi Raj Sharma Sharumathi Jeyasankar Priya Rani Radha Krishan Shandil Shridhar Narayanan Durga Chilakalapudi Rao Vijaya Source Type: research
Viruses and autism: A Bi-mutual cause and effect
World J Virol. 2023 Jun 25;12(3):172-192. doi: 10.5501/wjv.v12.i3.172.ABSTRACTAutism spectrum disorder (ASD) is a group of heterogeneous, multi-factorial, neurodevelopmental disorders resulting from genetic and environmental factors interplay. Infection is a significant trigger of autism, especially during the critical developmental period. There is a strong interplay between the viral infection as a trigger and a result of ASD. We aim to highlight the mutual relationship between autism and viruses. We performed a thorough literature review and included 158 research in this review. Most of the literature agreed on the poss...
Source: Herpes - July 3, 2023 Category: Infectious Diseases Authors: Mohammed Al-Beltagi Nermin Kamal Saeed Reem Elbeltagi Adel Salah Bediwy Syed A Saboor Aftab Rawan Alhawamdeh Source Type: research
