• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Fight Aging! Newsletter, December 6th 2021
In this study, they found these drugs can kill senescent cells from cultures of human fat tissue. The tissue was donated by individuals with obesity who were known to have metabolic troubles. Without treatment, the human fat tissues induced metabolic problems in immune-deficient mice. After treatment with dasatinib and quercetin, the harmful effects of the fat tissue were almost eliminated. Targeting p21Cip1 highly expressing cells in adipose tissue alleviates insulin resistance in obesity Insulin resistance is a pathological state often associated with obesity, representing a major risk factor for type 2...
Source: Fight Aging! - December 5, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Medium-term Influence of the Coronavirus Disease 2019 Pandemic on Patients with Diabetes: A Single-center Cross-sectional Study
Conclusions The COVID-19 pandemic has had a considerable medium-term impact on the lifestyle and mental health of patients with diabetes. Lifestyle changes were associated with glycemic and body weight control, and mental health changes were associated with lifestyle changes. These findings may provide important information on diabetes care during the pandemic.PMID:34803093 | DOI:10.2169/internalmedicine.8010-21
Source: Internal Medicine - November 22, 2021 Category: Internal Medicine Authors: Yumiko Maruo Yoko Irie Yoshinari Obata Kana Takayama Hiroki Yamaguchi Motohiro Kosugi Yoji Hazama Tetsuyuki Yasuda Source Type: research

Fight Aging! Newsletter, June 21st 2021
This study showed that the leakage of this mitochondrial nucleic material may occur as a result of mitochondrial dysfunction, which may involve genetic mutations in genes encoding mitochondrial proteins or incomplete degradation of mitochondrial dsDNA in the lysosome - which is a 'degradation factory' of the cell. Upon the leakage into the cytoplasm, this undegraded dsDNA is detected by a 'foreign' DNA sensor of the cytoplasm (IFI16) which then triggers the upregulation of mRNAs encoding for inflammatory proteins." Using a PD zebrafish model (gba mutant), the researchers demonstrated that a combination of PD-like ph...
Source: Fight Aging! - June 20, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Fight Aging! Newsletter, March 15th 2021
In conclusion, PLG attenuates high calcium/phosphate-induced vascular calcification by upregulating P53/PTEN signaling in VSMCs. Tsimane and Moseten Hunter-Gatherers Exhibit Minimal Levels of Atrial Fibrillation https://www.fightaging.org/archives/2021/03/tsimane-and-moseten-hunter-gatherers-exhibit-minimal-levels-of-atrial-fibrillation/ Epidemiological data for the Tsimane and Moseten populations in Bolivia shows that they suffer very little cardiovascular disease in later life, despite a presumably greater lifetime burden of infectious disease (and consequent inflammation) than is the case for people i...
Source: Fight Aging! - March 14, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

IJERPH, Vol. 17, Pages 7073: Preliminary Trajectories in Dietary Behaviors during the COVID-19 Pandemic: A Public Health Call to Action to Face Obesity
ovanni De Pergola The world is currently struggling to face the coronavirus pandemic (COVID-19), and many countries have imposed lockdowns and recommended quarantine to limit both the spread of the virus and overwhelming demands for medical care. Direct implications include the disruption of work routines, boredom, depression, increased calorie consumption, and other similar harmful effects. The present narrative review article briefly analyzes the preliminary effects of the quarantine lifestyle from the standpoint of dietary habits. In six different databases, we searched for original articles up to 10 August 2020, as...
Source: International Journal of Environmental Research and Public Health - September 26, 2020 Category: Environmental Health Authors: Roberta Zupo Fabio Castellana Rodolfo Sardone Annamaria Sila Vito Angelo Giagulli Vincenzo Triggiani Raffaele Ivan Cincione Gianluigi Giannelli Giovanni De Pergola Tags: Review Source Type: research

Food insecurity, COVID-19, and eating disorders
In this study, participants with the highest level of food insecurity experienced: higher levels of binge eating (uncontrollable eating) a higher likelihood of having any type of eating disorder, such as anorexia or bulimia dietary restraint for any reason, for example, avoiding a food group, such as carbohydrates, or types of foods, such as desserts weight self-stigma, assessed through responses to a questionnaire that measured self-devaluation and fear of experiencing stigma (sample statement: “I would never have any problems with weight if I were stronger”) high levels of worry, also measured through responses to a...
Source: Harvard Health Blog - August 17, 2020 Category: Consumer Health News Authors: Fatima Cody Stanford, MD, MPH, MPA, FAAP, FACP, FTOS  Tags: Coronavirus and COVID-19 Health Health care disparities Nutrition Source Type: blogs

Getting Off the Roller Coaster of Emotional Eating
With spending so many hours inside, it can be so easy to seek comfort in food. Especially when some of us have enormous stock piles of tasty snacks and quick shelf stable carbohydrates like cereal, pasta and rice. Perhaps emotional eating is a new phenomena or we’ve struggled over the years with binge eating. Binge-eating is defined as consuming unusually large amounts of food typically in a short period of time and feeling unable to stop eating. During these stressful times we want to maintain emotional, mental and physical balance. Ensuring that we are getting the right nutrients without the self harm of overeating is ...
Source: Psych Central - May 3, 2020 Category: Psychiatry Authors: Ivy Branin, ND Tags: Binge Eating Coronavirus Eating Disorders COVID-19 Cravings Emotional Eating emotional overeating Source Type: news