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Acute motor-sensory axonal polyneuropathy variant of Guillain-Barr é syndrome with a thalamic lesion and COVID-19: a case report and discussion on mechanism
ConclusionThe AMSAN variant of GBS secondary to COVID-19 infection is severe and can cause extensive damage to the peripheral nerves system. The deterioration of symptoms in the patient after early immunotherapy may indicate treatment-related fluctuation (TRF) and could be attributed to immune rebound. Moreover, an excessive immune response post-COVID-19 infection may trigger concurrent damage to the central nervous system, indicating secondary harm to brain small blood vessels and nerve units. For suspected cases of GBS complicated by COVID-19, it is essential to conduct early brain MRI examinations in addition to routine...
Source: Frontiers in Neurology - September 14, 2023 Category: Neurology Source Type: research

Coronavirus and its terrifying inning around the globe: The pharmaceutical cares at the main frontline
Chemosphere. 2021 Feb 16;275:129968. doi: 10.1016/j.chemosphere.2021.129968. Online ahead of print.ABSTRACTA novel coronavirus (2019-nCoV) is an acute life-threatening disease, emerged in China, which imposed a potentially immense toll in terms of public health emergency due to high infection rate and has a devastating economic impact that attracts the world's attention. After that, on January 30, 2020, it was officially declared as a global pandemic by World Health Organization (WHO). The International Committee on Taxonomy of Viruses (ICTV) recognized it as a Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) a...
Source: Chemosphere - March 2, 2021 Category: Chemistry Authors: Muneeb Ullah Abdul Wahab Sumbul Saeed Shahid Ullah Khan Haider Ali Shah Humayun Banzeer Ahsan Abbasi Shah Saud Khalid Naveed Sher Aslam Khan Shah Fahad Source Type: research

Increased circulating level of interleukin-6 and CD8 + T cell exhaustion are associated with progression of COVID-19
ConclusionsOlder age and higher levels of C-reactive protein, procalcitionin, interleukin-6, and lactate might predict COVID-19 progression. T lymphocyte, especially CD8+ cell-mediated immunity is critical in recovery of COVID-19. This study may help in predicting disease progression and designing immunotherapy for COVID-19.
Source: Infectious Diseases of Poverty - November 25, 2020 Category: Infectious Diseases Source Type: research

COVID-19: respuesta inmune y perspectivas terap éuticas.
COVID-19: respuesta inmune y perspectivas terapéuticas. Rev Peru Med Exp Salud Publica. 2020 Apr-Jun;37(2):312-319 Authors: Lozada-Requena I, Núñez Ponce C Abstract Disease caused by the new coronavirus (COVID-19) is characterized by fever, cough, and affection of the lower respiratory tract. It is associated with age, comorbidities and a weakened immune system. Typically, lymphopenias have been evidenced in severe cases and an excessive production of inflammatory cytokines (cytokine storm), which would explain the role of the hyperinflammatory response in the pathogenesis of COVID-19. Secondary inf...
Source: Revista Peruana de Medicina de Experimental y Salud Publica - September 4, 2020 Category: International Medicine & Public Health Tags: Rev Peru Med Exp Salud Publica Source Type: research

Coronavirus Could Upend Cancer Trends in the U.S.
Liz Satterfield has a ritual for every time she returns home after leaving the house. Diagnosed with metastatic breast cancer in 2016, the Kirkland, Washington resident recently learned that the cancer that had spread to her brain in 2018 was still growing. Throughout the pandemic, she’s had to visit the hospital at least once every three weeks, often more frequently, for treatments to control her disease. “I have a pair of shoes in a paper bag that I keep in the trunk of my car or a rack in the garage. I only wear those shoes when I’m going in to get treatment,” she says. “When I come home, I...
Source: TIME: Health - June 29, 2020 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized COVID-19 Source Type: news

Mesothelioma Survivors Face Critical COVID-19 Challenges
As the U.S. comes to grips with the challenges of the COVID-19 pandemic, mesothelioma cancer survivors face additional hurdles, including difficulty receiving care. Patients currently undergoing treatment for cancer and those who are immunocompromised are at greater risk of serious health issues if they contract COVID-19, according to the Centers for Disease Control and Prevention. “Cancer patients are a high-risk group and should be extra vigilant in terms of isolation precautions. They should follow the medical authorities’ instructions,” Dr. Ory Wiesel, a thoracic surgeon at Maimonides Medical Center in New York,...
Source: Asbestos and Mesothelioma News - March 26, 2020 Category: Environmental Health Authors: Matt Mauney Source Type: news