A Term Infant Presenting with COVID-19 Disease at Birth and a Croup-like Cough
Conclusion: As the COVID-19 virus mutates over time, there are some seemingly different presentations in both the pediatric and adult populations. The hypervigilance and sharing of new findings among providers is paramount in the treatment of infants with COVID-19 disease. [...] Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor , NY 10001 New York, USAArticle in Thieme eJournals: Table of contents | Abstract (Source: American Journal of Perinatology)
Source: American Journal of Perinatology - August 31, 2022 Category: Perinatology & Neonatology Authors: Arnold, Michelle Wade, Christine Micetic, Becky Mody, Kartik Tags: Short Communication Source Type: research
Dornase alfa in Cystic Fibrosis: indications, comparative studies and effects on lung clearance index
AbstractCystic fibrosis (CF) is the most common inherited disease in Caucasian populations, affecting around 50,000 patients in Europe and 30,000 in United States. A mutation in CF trans-membrane conductance regulator (CFTR) gene changes a protein (a regulated chloride channel), which is expressed in many tissues. DefectiveCFTR results in reduced chloride secretion and an overage absorption of sodium across the epithelia, leading to thickened secretions in organs such as pancreas and lung. Gradually, there have been considerable improvements in the survival of people with CF, thanks to substantial changes in specialized CF...
Source: Italian Journal of Pediatrics - August 4, 2022 Category: Pediatrics Source Type: research
Dornase alfa in Cystic Fibrosis: indications, comparative studies and effects on lung clearance index
Cystic fibrosis (CF) is the most common inherited disease in Caucasian populations, affecting around 50,000 patients in Europe and 30,000 in United States. A mutation in CF trans-membrane conductance regulator (C... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - August 4, 2022 Category: Pediatrics Authors: Vito Terlizzi, Chiara Castellani, Giovanni Taccetti and Beatrice Ferrari Tags: Review Source Type: research
Severe Pulmonary Hemorrhage in a Neonate With Hypoxic Ischemic Encephalopathy and Sepsis Managed on Extracorporeal Membrane Oxygenation
We describe the therapeutic strategies used on veno-arterial ECMO to successfully manage this infant, including clamping the endotracheal tube, aggressive correction of coagulopathy, and use of dornase alfa, as well as elaborate on the subtle changes in ECMO parameters during the run that preceded worsening pneumonia with sepsis. (Source: ASAIO Journal)
Source: ASAIO Journal - June 1, 2022 Category: Medical Devices Tags: Case Reports Source Type: research
WS07.01 Investigating the effects of dornase alfa and hypertonic saline used in combination on lung function in people with cystic fibrosis
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 1, 2022 Category: Respiratory Medicine Authors: E. Granger, G. Davies, R. Keogh Tags: Oral Sessions Source Type: research
P096 Tolerability of tigerase (dornase alfa) in children
(Source: Journal of Cystic Fibrosis)
Source: Journal of Cystic Fibrosis - June 1, 2022 Category: Respiratory Medicine Authors: V. Shadrina, E. Kondratyeva, E. Furman, A. Voronkova, V. Sherman, E. Zhekaite, O. Simonova, M. Mukhina, O. Vysokolova, E. Yakushina, N. Ilenkova, S. Trishina, O. Golubtsova, Y. Pinegina, T. Safonova, E. Vasilyeva, S. Akeliev Tags: Poster Sessions Source Type: research
Modified regimen intrapleural alteplase with pulmozyme in pleural infection management: a tertiary teaching hospital experience
Current management of poorly draining complex effusions favours less invasive image-guided placement of smaller tubes and adjunctive intrapleural fibrinolysis therapy (IPFT). In MIST-2 trial, intrapleural 10 m... (Source: BMC Pulmonary Medicine)
Source: BMC Pulmonary Medicine - May 17, 2022 Category: Respiratory Medicine Authors: Xiong Khee Cheong, Andrea Yu-Lin Ban, Boon Hau Ng, Nik Nuratiqah Nik Abeed, Nik Azuan Nik Ismail, Nik Farhan Nik Fuad, Syed Zulkifli Syed Zakaria, Sheah Lin Ghan and Mohamed Faisal Abdul Hamid Tags: Research Source Type: research
