Comparison of the efficacy and safety of tacrolimus monotherapy and cyclophosphamide combined with glucocorticoid in the treatment of adult primary membranous nephropathy: protocol of a multicenter, randomized, controlled, open study
This study will test whether treatment with TAC monotherapy is superior to CTX with glucocorticoid in inducing long-term remission of proteinuria in patients with adult IMN. The role of serum anti-PLA2R antibodies in the early assessment of the response to therapy using different therapeutic regimens will also be clarified.Trial registrationClinicalTrials.gov ChiCTR1800016140. Registered 12 June 2017.http://www.chictr.org.cn. (Source: Trials)
Source: Trials - February 23, 2020 Category: Research Source Type: clinical trials
Treatment effects of Chinese medicine (Yi-Qi-Qing-Jie herbal compound) combined with immunosuppression therapies in IgA nephropathy patients with high-risk of end-stage renal disease (TCM-WINE): study protocol for a randomized controlled trial
DiscussionThe TCM-WINE study will evaluate the effects and safety of YQF combined therapy compared with immunosuppression monotherapy on the basis of the optimal supportive treatment in high-risk IgAN. The evidence from this study will provide a novel, effective, and safe Chinese characteristic therapy for high-risk IgAN patients.Trial registrationClinicalTrials.gov,NCT03418779. Registered on 18 June 2018. (Source: Trials)
Source: Trials - January 5, 2020 Category: Research Source Type: clinical trials
Chinese herbal medicine Tangshen Formula treatment for type 2 diabetic kidney disease in the early stage: study protocol for a randomized controlled trial
DiscussionWe hypothesize that patients with type 2 diabetes in the early stage of DKD will benefit from TSF. If successful, this study will provide evidence-based recommendations for clinicians.Trial registrationClinicalTrials.gov,NCT03009864. Registered January 2017. (Source: Trials)
Source: Trials - December 20, 2019 Category: Research Source Type: clinical trials
Effects of Whole Food, Plant-Based Nutrition on Chronic Kidney Disease With Proteinuria
Conditions: Chronic Kidney Disease Stage 3B; Chronic Kidney Disease, Stage 4; Proteinuria Intervention: Other: whole food, plant-based diet Sponsor: University of Rochester Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 21, 2019 Category: Research Source Type: clinical trials
