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Efficacy of belimumab combined with rituximab in severe systemic lupus erythematosus: study protocol for the phase 3, multicenter, randomized, open-label Synbiose 2 trial
DiscussionThe Synbiose 2 trial is the first multicenter phase 3 clinical trial investigating combined B cell targeted therapy in SLE, including lupus nephritis. The outcome of this study will provide further evidence for the clinical efficacy of this new treatment strategy in severe SLE.Trial registrationClinicalTrials.govNCT03747159. Registered on 20 November 2018. (Source: Trials)
Source: Trials - November 12, 2022 Category: Research Source Type: clinical trials

Intravenous Treatments Used in Medication Overuse Headache Bridge Treatment
Condition:   Medication Overuse Headache Interventions:   Other: Intravenous hydration;   Other: Intravenous prednisolone;   Other: Intravenous lidocaine Sponsor:   Diskapi Teaching and Research Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 8, 2022 Category: Research Source Type: clinical trials