Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
Probing the mechanical properties of ORF3a protein, a transmembrane channel of SARS-CoV-2 virus: Molecular dynamics study
Chem Phys. 2023 May 1;569:111859. doi: 10.1016/j.chemphys.2023.111859. Epub 2023 Feb 23.ABSTRACTSARS-CoV-2-encoded accessory protein ORF3a was found to be a conserved coronavirus protein that shows crucial roles in apoptosis in cells as well as in virus release and replications. To complete the knowledge and identify the unknown of this protein, further comprehensive research is needed to clarify the leading role of ORF3a in the functioning of the coronavirus. One of the efficient approaches to determining the functionality of this protein is to investigate the mechanical properties and study its structural dynamics in the...
Source: Chemical Physics - February 28, 2023 Category: Chemistry Authors: Vahid Mahmoudi Maymand Omid Bavi Abbas Karami Source Type: news
'Do we know if we need to reduce head impact exposure?': A mixed-methods study highlighting the varied understanding of the long-term risk and consequence of head impact exposure across all stakeholders at the highest level of rugby union - Starling LT, McKay C, Cross M, Kemp S, Stokes KA.
BACKGROUND: One strategy to prevent and manage concussion is to reduce head impacts, both those resulting in concussion and those that do not. Because objective data on the frequency and intensity of head impacts in rugby union (rugby) are sparse, stakehol... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
A K-means clustering method with feature learning for unbalanced vehicle fault diagnosis - Wang B, Wang G, Wang Y, Lou Z, Hu S, Ye Y.
PURPOSE Vehicle fault diagnosis is a key factor in ensuring the safe and efficient operation of the railway system. Due to the numerous vehicle categories and different fault mechanisms, there is an unbalanced fault category problem. Most of the current me... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Bi-level optimization of long-term highway work zone scheduling considering elastic demand - Li Y, Fan W.
PURPOSE More and more work zone projects come with the needs of new construction and regular maintenance-related investments in transportation. Work zone projects can have many significant impacts socially, economically and environmentally. Minimizing the ... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Blind source extraction based on EMD and temporal correlation for rolling element bearing fault diagnosis - Zhao X, Qin Y, Fu H, Jia L, Zhang X.
PURPOSE Fault diagnosis methods based on blind source separation (BSS) for rolling element bearings are necessary tools to prevent any unexpected accidents. In the field application, the actual signal acquisition is usually hindered by certain restrictions... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Examining partial proportional odds model in analyzing severity of high-speed railway accident - Wang J, Wang Y, Peng Y, Lu JJ.
PURPOSE The operation safety of the high-speed railway has been widely concerned. Due to the joint influence of the environment, equipment, personnel and other factors, accidents are inevitable in the operation process. However, few studies focused on iden... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Intersection control strategy optimization based on exchangeable lanes modeling - Liu B, Hou J, Ma X, Shi M, Lu S, Wang R.
PURPOSE Due to the conflicts between left turn traffic and opposite straight-going traffic in urban traffic network, some of the traffic lanes cannot be used to discharge vehicles during its green phases and the intersection capacity can be greatly reduced... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Modeling and simulation of vehicle group lane-changing behaviors in upstream segment of ramp areas under a connected vehicle environment - Li H, Huang Z, Qin L, Zheng S, Yang Y.
PURPOSE The purpose of this study is to effectively optimize vehicle lane-changing behavior and alleviate traffic congestion in ramp area through the study of vehicle lane-changing behaviors in upstream segment of ramp areas. DESIGN/METHODOLOGY/APP... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Question answering system for deterministic fault diagnosis of intelligent railway signal equipment - Liu H, Wang Y, Zhou X, Lou Z, Ye Y.
PURPOSE The railway signal equipment failure diagnosis is a vital element to keep the railway system operating safely. One of the most difficulties in signal equipment failure diagnosis is the uncertainty of causality between the consequence and cause for ... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Reliability analysis on the train control system in the CTCS-3 operating mode - Shi L, Wang J.
PURPOSE This paper aims to study the reliability of the high-speed train operation control system in the Chinese Train Control System Level 3 (CTCS-3) operating mode. DESIGN/METHODOLOGY/APPROACH Dynamic fault tree and Bayesian network method are ad... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
Resilience concepts in integrated urban transport: a comprehensive review on multi-mode framework - Du Y, Wang H, Gao Q, Pan N, Zhao C, Liu C.
PURPOSE Resilience concepts in integrated urban transport refer to the performance of dealing with external shock and the ability to continue to provide transportation services of all modes. A robust transportation resilience is a goal in pursuing transpor... (Source: SafetyLit)
Source: SafetyLit - February 27, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
A feedforward neural network for drone accident prediction from physiological signals - Sakib MN, Chaspari T, Behzadan AH.
PURPOSE As drones are rapidly transforming tasks such as mapping and surveying, safety inspection and progress monitoring, human operators continue to play a critical role in ensuring safe drone missions in compliance with safety regulations and standard o... (Source: SafetyLit)
Source: SafetyLit - February 25, 2023 Category: International Medicine & Public Health Tags: Engineering, Physics, Structural Soundness and Failure Source Type: news
