Early Dietary Treated Patients With Phenylketonuria Can Achieve Normal Growth and Mental Development.
Condition: Phenylketonurias Intervention: Dietary Supplement: phenylalanine restricted diet Sponsor: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 10, 2020 Category: Research Source Type: clinical trials
Impact of phenylalanine on cognitive, cerebral, and neurometabolic parameters in adult patients with phenylketonuria (the PICO study): a randomized, placebo-controlled, crossover, noninferiority trial
DiscussionUsing a combination of neuropsychological and neuroimaging data, the PICO Study will considerably contribute to improve the currently insufficient level of evidence on how adult patients with early-treated PKU should be managed.Trial registrationThe study is registered at clinicaltrials.gov (NCT03788343) on the 27th of December 2018, at kofam.ch (SNCTP000003117) on the 17th of December 2018, and on the International Clinical Trials Registry Platform of the WHO. (Source: Trials)
Source: Trials - February 12, 2020 Category: Research Source Type: clinical trials
An Observational, Cross-sectional Study Into the Future Cardiovascular Disease (CVD) Risk of Phenylketonuria (PKU) Patients on a Low Phenylalanine Treatment Diet (LPD).
Conditions: Phenylketonurias; Cardiovascular Diseases Interventions: Diagnostic Test: Carotid intima media thickness measurement; Diagnostic Test: Pulse Wave Velocity measurement; Diagnostic Test: Ankle brachial pressure index; Other: Diet questionnaire and diet diary; Other: Routine blood samples Sponsor: Guy's and St Thomas' NHS Foundation Trust Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 5, 2020 Category: Research Source Type: clinical trials
