Case of the Week 729
This week ' s case was generously donated by Drs. Jacob Rattin, Anisha Misra, and Hannah Wang, and originally identified by Marissa Roberts. The following objects were seen on a trichrome-stained stool specimen and measure approximately 15 micrometers in length. What is your identification? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - November 2, 2023 Category: Parasitology Source Type: blogs
Answer to Case 729
Answer to theParasite Case of the Week 729: Trophozoites of Chilomastix mesniliBelow is an answer written by Dr. Jacob Rattin (@EternalStudying):This non-pathogenic flagellate has pear-shaped trophozoites that are 6 – 24 μm long with a longitudinal spiral groove running along the body (not seen in this specimen). If visualized in a fresh prep, the motility may allow the spiral groove to be seen as the organism turns (seeCase 475). The trophozoite has one nucleus (arrowhead), usually at the anterior end, with an eccentric karyosome and a cytostome (oral groove) close by. The posterior end tapers to a poi...
Source: Creepy Dreadful Wonderful Parasites - November 1, 2023 Category: Parasitology Source Type: blogs
Case of the Week 728
This week ' s case was donated by Drs. Meredith Kavalier, Megan Shaughnessy, and David Cartwright. The patient has a history of treated urothelial cell carcinoma and remote travel to Asia. The cytopathologist was concerned by the presence of the following structures seen in a routine screening urine sample. How would you interpret these findings? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - October 11, 2023 Category: Parasitology Source Type: blogs
Answer to Case 728
Answer to theParasite Case of the Week 728: Not a parasite egg; uric acid crystals.Uric acid crystals are a very convincing mimic ofSchistosoma haematobiumeggs! They are both found in urine, and they both have a terminal spine. However, there are a number of features that can be used to easily differentiate the two:Uric acid crystals vary in size and shape and are often much smaller thanS. haematobiumeggs. In contrast, S. haematobium eggs are regular in size and shape, and quite large (approximately 150 micrometers in length).Uric acid crystals commonly have points on both ends instead of the single ' pinched-off ' s...
Source: Creepy Dreadful Wonderful Parasites - October 10, 2023 Category: Parasitology Source Type: blogs
Case of the Week 727
his week ' s case was generously donated by Dr. Richard Bradbury. The following structure was seen in a concentrated wet prep of stool. It measures approximately 80 micrometers in diameter. Check out the video to see this structure in multiple planes. Identification? (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - September 26, 2023 Category: Parasitology Source Type: blogs
Answer to Case 727
Answer to theParasite Case of the Week 727:Hymenolepis diminutaAs noted by Lamia Gala on LinkedIn, " The distance between the outer and the inner shell is large with no polar filaments " which is consistent withH. diminuta.This is in contrast toRodentolepis(formerlyHymenolepis)nana, which does have polar filaments between the outer and inner shell.H. diminutais also slightly larger thanR. nana, measuring 70-85 micrometers in greatest dimension (compared to 30-50 forR. nana). Florida Fan provided the helpful memory aid that the word " diminuta " is larger in size than " nana " , which also applies to their eggs (thank...
Source: Creepy Dreadful Wonderful Parasites - September 25, 2023 Category: Parasitology Source Type: blogs
Case of the Week 726
This weeks case features the following small, oval-shaped, red-staining objects seen in a bronchoalveolar specimen from an immunocompromised patient. The stain is a strong trichrome (chromatrope 2R method). Identification? What is the significance of this finding? (CLICK ON IMAGES TO ENLARGE) (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - September 18, 2023 Category: Parasitology Source Type: blogs
Answer to Case 726
Answer to theParasite Case of the Week 726: Microsporidia spores; genus and species not determinedThese small spores stain deep red with the chromotrope 2R method and its modifications. They are oval shaped and often have a darker-staining equatorial band in the middle of the spore. Spores ofEnterocytozoon bieneusiare very small (0.8 to 1.4 micrometers long), whereas other species such asEncephalitozoonspp.,Vittaforma cornea,andAnncaliia algeraeare a little larger. Some (e.g.,Anncaliia) are up to 4 micrometers long and may be mistaken for small years such asHistoplasma capsulatum(especially because they are focally G...
Source: Creepy Dreadful Wonderful Parasites - September 17, 2023 Category: Parasitology Source Type: blogs
Fight Aging! Newsletter, September 18th 2023
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter,
please visit:
https://www.fightaging.org/newsletter/
Longevity Industry Consulting Services
Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - September 17, 2023 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Short Term Fasting Enhances the Immune Function of Red Blood Cells
A number of lines of research suggest that forms of calorie restriction and fasting can improve the function of the immune system. It is also noted that fasting can reduce the number of immune cells found in the circulation. The complement system is a part of the innate immune system, reacting to invading pathogens in order to rouse immune cells to action. Red blood cells play a part in the complement system, and researchers here show that fasting can improve the immune response despite a lower number of circulating white blood cells by improving the ability of red blood cells to trigger a response.
Fasting is kno...
Source: Fight Aging! - September 12, 2023 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Case of the Week 725
This week ' s interesting case is generously donated by Dr. Justin Juskewitch. Hopefully all of you have been able to avoid this so far this summer! The patient is a young girl who developed this very itchy rash about 30 minutes after a swim in a fresh water lake in Maine (Northeastern United States). The rash developed to what is shown below over a period of several hours. Her two siblings had a similar presentation. All three children had resolution of itching with benadryl, corticosteroid cream, and oatmeal body wash baths over the next few hours, but the rash lasted for 5-7 days.What is the most likely diagno...
Source: Creepy Dreadful Wonderful Parasites - September 5, 2023 Category: Parasitology Source Type: blogs
Answer to Case 725
Answer toParasite Case of the Week 725: Swimmer ' s itchAs noted by Florida Fan, this is " typical swimmer ’s itch, also known by other names depending on the activity of the patient like ' clam digger ’s itch ' or ' duck itch ' . " (Also called Pelican itch in Australia) " All are caused by [zoonotic] cercariae in most freshwater bodies of water frequented by ducks and/or water birds. The cercariae penetrate the skin and cause a cercarial dermatitis. This summer is so hot even in the Northern most states that a quick plunge into the lake is certainly very appealing. We may expect to see more cases like this one....
Source: Creepy Dreadful Wonderful Parasites - September 3, 2023 Category: Parasitology Source Type: blogs
Case of the Week 724
This week ' s case was generously donated by Dr. Nazia Nagi in New Delhi, India. She saw these ' cute ' little objects (around 15 micrometers long) during her rotation in the Diarrhoeal Laboratory. The patient is a young teenager with diarrhea lasting for 15-17 days. Identification?Saline wet mounts:Iodine wet mount: (Source: Creepy Dreadful Wonderful Parasites)
Source: Creepy Dreadful Wonderful Parasites - August 16, 2023 Category: Parasitology Source Type: blogs
Answer to Case 724
Answer to theParasite Case of the Week 724:Giardia duodenalistrophozoites and cysts.Florida Fan eloquently described the characteristic motility pattern ofGiardiatrophozoites: " Beautiful autumn leaves falling in the wind in a sliding side to side motion. " He also notes that "Giardiatrophozoites and cysts can present a little challenge to parasitologists at times. Most of us are used to see the typical kite-shaped trophozoite with its nuclei, sucking disks and flowing flagella. When these trophozoites turn sideways, we may see only ạ leafy profile, and when they stand on their tails they will look like the kid nex...
Source: Creepy Dreadful Wonderful Parasites - August 15, 2023 Category: Parasitology Source Type: blogs
The Apple Leaf Miner, Lyonetia clerkella
The Apple Leaf Miner Moth, Lyonetia clerkella, is a tiny insect with a wingspan of just 7-9 millimetres. It is widely distributed across the UK. Its larvae burrow under the surface of the leaves of apple trees (Malus) and Prunus species. Leaving a trail through the leaf known as a leaf mine.
Apple Leaf Miner, Lyonetia clerkella
This species of moth is double brooded. The second or a subsequent brood will hibernate/overwinter and reappear in the spring. The adults are night flyers and attracted to light, hence my photo of one drawn to my 20W actinic Skinner moth trap last night.
Closer view of Apple Leaf Miner, Lyonetia cle...
Source: David Bradley Sciencebase - Songs, Snaps, Science - August 4, 2023 Category: Science Authors: David Bradley Tags: Sciencebase Source Type: blogs
