Intensive Weight Loss Intervention Versus Bariatric Surgery for Adults With Severe and Complex Obesity: the LightBAR Randomised Trial
Conditions: Obesity Interventions: Behavioral: Intensive weight loss intervention; Procedure: Bariatric surgery Sponsors: Carsten Dirksen; University of Copenhagen; University of Southern Denmark; University of Oxford; University of Bristol; Copenhagen Trial Unit, Center for Clinical Intervention Research Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
INvestigating the Value of Early Sleep Therapy
Conditions: Acute Insomnia (Disorder) Interventions: Behavioral: Sleep Restriction Therapy (SRT); Behavioral: Sleep Hygiene Education (SHE) Sponsors: University of Strathclyde; University of Oxford; University of Glasgow; NHS Greater Glasgow and Clyde; NHS Grampian Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials
MOdifiable facTors to Improve VentilAtion ThErapy in ICU
Conditions: Critical Illness; Invasive Mechanical Ventilation; ICU Mortality; Developing Countries; Risk Factors Sponsors: Nat Intensive Care Surveillance - MORU; D ' Or Institute for Research and Education; University of Oxford; Wellcome Trust; Makerere University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 1, 2024 Category: Research Source Type: clinical trials
A Long-term Observational Study Evaluating the Presentation and Management of Acute Respiratory Tract Infections in Primary Care Across Europe
Conditions: Acute Respiratory Tract Infection Sponsors: European Clinical Research Alliance for Infectious Diseases (ECRAID); UMC Utrecht; University of Oxford; Universiteit Antwerpen Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials
ENHANCE-EvideNce Led Co-created HeAlth Systems interventioNs for MLTCs CarE
Conditions: HIV Infections; Hypertension; Diabetes Mellitus; Asthma; Depression; Myocardial Infarction; Stroke Interventions: Other: ENHANCE intervention (health systems) Sponsors: University of KwaZulu; University of Cape Town; King ' s College London; University of East Anglia; University of Oxford; Medical Research Council, South Africa Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials
BCG Revaccination Study in Diabetic and Non-Diabetic Adults
Conditions: Tuberculosis Interventions: Biological: BCG Danish Sponsors: University of Oxford Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 7, 2024 Category: Research Source Type: clinical trials
Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression
Conditions: Aneurysm Abdominal; Peripheral Arterial Disease Interventions: Other: No intervention, retrospective study Sponsors: Amsterdam UMC, location VUmc; Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA); Technical University of Twente; Universidade do Porto; Centre Hospitalier Universitaire de Nice; Stichting Allai; Faculty of Medicine, University of Belgrade; Brightfish Be; Hospital District of Helsinki and Uusimaa; University of Bergen; Asklepios Kliniken Hamburg GmbH; University of Oxford; VIN ČA INSTITUTE OF NUCLEAR SCIENCES Belgrado Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Postpartum Primaquine in Breast Milk
Conditions: Postpartum Women Interventions: Drug: Primaquine Sponsors: University of Oxford; Mahidol Oxford Tropical Medicine Research Unit Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 4, 2024 Category: Research Source Type: clinical trials
Hypertension Explored in Long-term Postpartum Follow-up in Later Life
Conditions: Hypertension; Cardiovascular Diseases; Cerebrovascular Disorders; Vascular Diseases Interventions: Other: Hypertensive pregnancy Sponsors: University of Oxford Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 1, 2024 Category: Research Source Type: clinical trials
A Controlled Human Infection Model (CHIM) With Intradermal BCG in Malawi
Conditions: Tuberculosis Interventions: Biological: BCG Sponsors: Liverpool School of Tropical Medicine; Liverpool School of Tropical Medicine, United Kingdom; Fred Hutchinson Cancer Center; University of Liverpool; Malawi-Liverpool-Wellcome Trust Clinical Research Programme; University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 21, 2023 Category: Research Source Type: clinical trials
In-vivo Transmission Model in Semi-immune Adults
Conditions: Controlled Human Malaria Infection; Induced Blood Stage Malaria Infection; Malaria Transmission; Malaria Challenge Interventions: Drug: Piperaquine tablets , which will be administered orally as a single dose of 480mg (320mg+160mg).; Drug: Doxycycline (100mg tablets strength as Doxycycline Hyclate) will also be administered orally and will be given as 1 tablet (100mg) Once daily for 7 days. Sponsors: Ifakara Health Institute; University of Oxford Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 15, 2023 Category: Research Source Type: clinical trials
Physiotherapy and Optimised Nutrition in Survivors of Critical Illness
Conditions: Critical Illness Interventions: Other: Structured physiotherapy and rehabilitation; Other: Standard care Sponsors: University Hospitals Coventry and Warwickshire NHS Trust; Oxford University Hospitals NHS Trust Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
A Study to Compare Two Dosing Regimens for a New Malaria Vaccine
Conditions: Malaria; Malaria,Falciparum; Protozoan Infections; Parasitic Disease; Infections; Vector Borne Diseases Interventions: Biological: Matrix M with RH5.1 Sponsors: University of Oxford Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 21, 2023 Category: Research Source Type: clinical trials
AI Assisted Detection of Fractures on X-Rays (FRACT-AI)
Conditions: Fracture; Bone Fracture; Dislocation; Fracture Multiple; Fractures, Closed; Fractures, Open Interventions: Other: Cases reading; Other: Ground truthing Sponsors: Oxford University Hospitals NHS Trust; Gleamer Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 14, 2023 Category: Research Source Type: clinical trials
Effects of Oral Iron Supplementation Before vs at Time of Vaccination on Immune Response in Iron Deficient Kenyan Women
Conditions: Iron Deficiency Anemia Interventions: Dietary Supplement: Iron supplementation; Biological: MenACWY vaccine; Biological: COVID-19 vaccine; Other: Placebo; Biological: Typhim Vi vaccine Sponsors: Swiss Federal Institute of Technology; Jomo Kenyatta University of Agriculture and Technology; University of Oxford Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 3, 2023 Category: Research Source Type: clinical trials
