FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC
Conditions: Ovarian Cancer; Non-small Cell Lung Cancer Interventions: Drug: TUB-040 Sponsors: Tubulis GmbH Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials

NM32-2668 in Adult Patients With Selected Advanced Solid Tumors
Conditions: Ovarian Carcinoma; Fallopian Tube Carcinoma; Peritoneal Carcinoma; Endometrial Cancer; Adenocarcinoma of Lung; Triple Negative Breast Cancer; Liposarcoma; Leiomyosarcoma; Mesothelioma, Malignant; Adenocarcinoma - Gastroesophageal Junction (GEJ); Adenocarcinoma of the Stomach; Melanoma, Malignant; Renal Cell Carcinoma Interventions: Biological: NM32-2668 Sponsors: Numab Therapeutics AG Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials

Frailty, Quality Of Life and Early Reversal of Temporary Defunctioning Stoma in Ovarian Cancer
Conditions: Ovarian Cancer Interventions: Other: Frailty and Quality of Life evaluation Sponsors: Sahar Salehi Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 7, 2024 Category: Research Source Type: clinical trials

Clonal Hematopoiesis in Ovarian Cancer Survivors and Risk of Secondary Blood Cancers
Conditions: Recurrent Fallopian Tube Carcinoma; Recurrent Ovarian Carcinoma; Recurrent Primary Peritoneal Carcinoma Interventions: Other: Non-Interventional Study Sponsors: University of Washington; National Cancer Institute (NCI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 6, 2024 Category: Research Source Type: clinical trials

Secondary Interval Cytoreductive Surgery in Platinum-sensitive Recurrent Epithelial Ovarian Cancer
Conditions: Recurrent Ovarian Carcinoma Interventions: Procedure: Carboplatin or cisplatin; Drug: Paclitaxel, gemcitabine or liposomal doxorubicin with or without bevacizumab or biosimilar; Drug: Bevacizumab or biosimilar; Procedure: Cytoreductive surgery Sponsors: The University of Hong Kong Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials

Open Label Study to Evaluate BL-M07D1 in HER2 Expressing Malignant Solid Tumors
Conditions: Endometrial Cancer; Cervical Cancer; Ovarian Cancer; Urothelial Carcinoma; Biliary Tract Cancer Interventions: Drug: BL-M07D1 Sponsors: SystImmune Inc. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 5, 2024 Category: Research Source Type: clinical trials

Verastem Oncology Receives Orphan Drug Designation from FDA for Avutometinib Alone or in Combination With Defactinib in Recurrent Low-Grade Serous Ovarian Cancer
BOSTON--(BUSINESS WIRE)--Mar. 5, 2024-- Verastem Oncology (Nasdaq: VSTM), a biopharmaceutical company committed to advancing new medicines for patients, today announced that the U.S. Food and Drug Administration (FDA) granted Orphan Drug Designation... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - March 5, 2024 Category: Pharmaceuticals Source Type: clinical trials

Study of Acute Normovolemic Hemodilution (ANH) in People With Ovarian Cancer Who Are Having Primary Cytoreductive Surgery
Conditions: Ovarian Cancer; Fallopian Tube Carcinoma; Ovarian Carcinoma; Peritoneal Carcinoma; Ovarian Cancer Stage IIIC; Fallopian Tube Cancer Stage IIIC; Ovarian Cancer Stage IV; Fallopian Tube Cancer Stage IV; Fallopian Tube Cancer; Peritoneal Cancer Interventions: Biological: Acute Normovolemic Hemodilution/ANH Sponsors: Memorial Sloan Kettering Cancer Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 4, 2024 Category: Research Source Type: clinical trials

A Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid Tumors
Conditions: Neoplasms; Non-small-cell Lung Cancer; Melanoma; Squamous Cell Carcinoma of the Head and Neck; Renal Cell Carcinoma; Urothelial Carcinoma; Colorectal Carcinoma; Ovarian Carcinoma Interventions: Drug: PF-07820435; Biological: Sasanlimab Sponsors: Pfizer Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials

Development and Validation of a Risk Prediction Model for Venous Thromboembolism in Gynecological Cancer Patients Undergoing Systemic Antineoplastic Treatment: The Gynecological Cancer Associated Thrombosis (GynCAT) Study
Conditions: Cancer-associated Thrombosis; Venous Thromboembolism; Gynecologic Cancer; Ovarian Cancer; Cervix Cancer; Endometrial Cancer; Vaginal Cancer Interventions: Drug: Anticoagulant Sponsors: Fondazione Policlinico Universitario Agostino Gemelli IRCCS; Fondazione Umberto Veronesi Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Treatment Pleural Carcinosis of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin Administration
Conditions: Mesothelioma, Malignant; Carcinoma, Non-Small-Cell Lung; Carcinoma Breast Stage IV; Ovarian Cancer; Esophageal Cancer; Gastric Cancer Interventions: Drug: Cisplatine Teva ® Sponsors: Dr Jean Yannis PERENTES Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

An Exploratory Clinical Study to Evaluate the Safety and Efficacy of NK Cells (Combined With Standard Therapy) in the Treatment of Solid Tumor Patients
Conditions: Solid Tumors (Pancreatic Cancer, Esophageal Cancer, Gastric Cancer, Cholangiocarcinoma, Lung Cancer and Ovarian Cancer) Interventions: Drug: Allogeneic NK (CCT-ANK-11) Sponsors: Escure Biotechnology Corp; Beijing Kejing Biotechnology Corp. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

The Exploration of Personalized ctDNA Based MRD in the Clinical Significance of Cervical Cancer
Conditions: Ovarian Cancer Sponsors: Geneplus-Beijing Co. Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 28, 2024 Category: Research Source Type: clinical trials

Administration of Hyperthermic Intraperitoneal Chemotherapy in the General Ward
Conditions: Epithelial Ovarian Cancer Interventions: Procedure: China Hyperthermic Intraperitoneal Chemotherapy(C-HIPEC) Sponsors: Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Shenshan Medical Center, Memorial Hospital of Sun Yat-sen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials

Phase 1, Safety and Tolerability Study of XmAb ®541 in Advanced Solid Tumors
Conditions: Ovarian Cancer; Endometrial Cancer; Germ Cell Tumor; Testicular Germ Cell Tumor; Ovarian Germ Cell Tumor Interventions: Biological: XmAb541 Sponsors: Xencor, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 26, 2024 Category: Research Source Type: clinical trials