How the Black Death got its start
00:46 Uncovering the origins of the Black DeathThe Black Death is estimated to have caused the deaths of up to 60% of the population of Europe. However, despite extensive research, the origin of this wave of disease has remained unclear. Now, by using a combination of techniques, a team have identified a potential starting point in modern day Kyrgyzstan.Research article: Spyrou et al.06:57 Research HighlightsThe cocktails of toxins produced by wriggling ribbon worms, and a tiny thermometer the size of a grain of sand.Research Highlight: A poisonous shield, a potent venom: these worms mean businessResearch Highlight: Mighty...
Source: Nature Podcast - June 15, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 906: Long COVID, giant viruses, and smallish pox
TWiV reviews human monkeypox infections, evidence for human Mimivrus infections, and incidence of long COVID in post-vaccine SARS-CoV-2 infections. Hosts: Vincent Racaniello, Dickson Despommier, Rich Condit, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox update (ProMedMail) Multi-country monkeypox outbreak (WHO) Monkeypox new global threat (Science) Monkeypox outbreak 9 US states (MMWR) Mimivirus in human respiratory samples (Sci Rep) Long COVID after post-vaccination infection (Nat Med) Letters read on TWiV 906 Timestamps b...
Source: This Week in Virology - MP3 Edition - June 5, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV Special: Monkeypox clinical update with Dr. Daniel Griffin
In this special episode, Dr. Griffin answers questions about the recent cases of monkeypox including their origin, clinical presentation, diagnosis, treatment, and overall risk. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Monkeypox multi-country outbreak risk assessment (pdf, ECDC) Monkeypox update (ProMedMail) Monkeypox virus genome sequences (Nextstrain) Intro music is by Ronald Jenkees Send your questions for Dr. Griffin to daniel@microbe.tv (Source: This Week in Virology - MP3 Edition)
Source: This Week in Virology - MP3 Edition - May 26, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 889: COVID-19 clinical update #110 with Dr. Daniel Griffin
In COVID-19 clinical update #110, Dr. Griffin covers hospital admissions during variant outbreaks, viral load in vaccinated and unvaccinated individuals, predictive capacity of symptoms in children, comparison of antigen tests, incidence of myocarditis after vaccination, steroids during replication phase, Paxlovid efficacy and safety, fluvoxamine, sabizabutin, colchicine, and prevalence of infection in Africa. Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Hospital admissions during Omicron and Delta variant outbreaks (Lancet) Viral load in unvaccinat...
Source: This Week in Virology - MP3 Edition - April 16, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Coronapod: How vaccine complacency is plaguing 'COVID zero' strategies
A handful of states around the world have pursued 'COVID zero' strategies. Through a combination of intensive lockdowns, travel restrictions and comprehensive test and trace systems, regions like Tonga, New Zealand, Taiwan, mainland China and Western Australia managed to keep the virus at bay. But now many of these countries are facing new outbreaks on a scale they have not yet seen, and it is being driven in part by vaccine hesitancy. In this episode of Coronapod we discuss how a successful public health campaign can breed new problems when it comes to public perception of risk, and ask how vaccine complacency m...
Source: Nature Podcast - March 18, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

TWiV 848: COVID-19 clinical update #95 with Dr. Daniel Griffin
In COVID-19 clinical update #95, Daniel Griffin discusses new CDC guidelines for isolation and quarantine, EUA for Molnupiravir, children and COVID, vaccine safety in 5-11 year olds, Omicron outbreaks in Nebraska and Denmark, Baylor's COVID vaccine, and COVID-OUT for ivermectin. Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Isolation and quarantine guidance (CDC) EUA for Molnupiravir (FDA) Children and COVID state data (AAP) Vaccine safety in 5-11 year olds (MMWR) Omicron and antigen tests (FDA) Omicron in Nebraska (MMWR) Omicron in Danish households (medRxiv) ...
Source: This Week in Virology - MP3 Edition - January 1, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 814: COVID-19 clinical update #83 with Dr. Daniel Griffin
In COVID-19 clinical update #83, Daniel Griffin discusses upcoming FDA discussions on vaccines, strategies to prevent transmission at youth camps, outbreaks at summer camps, impact of vaccination on transmission, AZD7442 request for EUA filed, EUA issued for home antigen test, phase 3 data on AZD1222 vaccine, 6 month effectiveness of Pfizer/BioNTech vaccine, estimates of durability of immunity against reinfection, Molnupiravir interim results, optimal time for monoclonal antibody infusion, IVIG plus Infliximab for MIS-C, and effect of vaccination on long COVID. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free)...
Source: This Week in Virology - MP3 Edition - October 9, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 805: Delta and boosters
The TWiVotopes review current evidence which does not show the need for widespread COVID-19 booster vaccination, and results of experiments to examine the replication and immune evasion of the SARS-CoV-2 delta variant. Hosts: Vincent Racaniello, Rich Condit, Kathy Spindler, and Brianne Barker Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode ASV Vaccine Town Halls Vaccine boosters not needed (Lancet) Delta variant replication and immune evasion (Nature) Epidemiologically linked COVID-19 outbreaks (MMWR) Letters read on TWiV 805 Timestamps by Jolene. Thanks! Weekly...
Source: This Week in Virology - MP3 Edition - September 16, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 800: COVID-19 clinical update #78 with Dr. Daniel Griffin
In COVID-19 clinical update #78, Daniel Griffin covers ivermectin, convalescent plasma, disease in pregnant women, children and COVID, delta outbreak in an elementary school, validation of at-home antigen test, shedding in infected vaccinated people, mRNA vaccine antibody responses compared, AZD7442, fluvoxamine, one year outcomes in hospitalized patients, and post-vaccination disease. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Do not take veterinary ivermectin (FDA) Ivermectin side effects (CDC) Do not use conva...
Source: This Week in Virology - MP3 Edition - September 4, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 790: COVID-19 clinical update #74 with Dr. Daniel Griffin
In COVID-19 clinical update #74, Daniel Griffin covers infections in vaccinated individuals, expansion of Regeneron monoclonal antibody cocktail for prophylaxis, neutralization of variants by antibodies produced by infection or vaccination, longer hospital stays associated with remdesivir treatment, and post-acute sequelae of nfection and impact on quality of life 1-6 months after illness. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Outbreak in Barnstable County, MA (MMWR) Kinetics of delta variant infections...
Source: This Week in Virology - MP3 Edition - August 7, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 790: COVID-19 clinical update #74 with Dr. Daniel Griffin
In COVID-19 clinical update #74, Daniel Griffin covers infections in vaccinated individuals, expansion of Regeneron monoclonal antibody cocktail for prophylaxis, neutralization of variants by antibodies produced by infection or vaccination, longer hospital stays associated with remdesivir treatment, and post-acute sequelae of infection and impact on quality of life 1-6 months after illness. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Outbreak in Barnstable County, MA (MMWR) Kinetics of delta variant infection...
Source: This Week in Virology - MP3 Edition - August 7, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 783: COVID-19 clinical update #72 with Dr. Daniel Griffin
In COVID-19 clinical update #72, Daniel Griffin covers long term symptoms in children, outcomes for MIS-C, recent guidance from the American Academy of Pediatrics, a large well traced outbreak of delta variant, low dose mRNA vaccination generates durable T cell memory and antibodies, protective immunity in recovered patients, assessment of BinaxNOW, no effect of oral azithromycin, post-discharge symptoms in Nigeria, and therapeutics for low and middle income countries. Hosts: Daniel Griffin and Vincent Racaniello Subscribe (free): iTunes, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode L...
Source: This Week in Virology - MP3 Edition - July 23, 2021 Category: Virology Authors: Vincent Racaniello Source Type: podcasts