Genomic Surveillance and Characterization of Microbial Threats Facilitates Early Detection and Containment of Disease Outbreaks in West Africa.
Dr. Christian Happy, has the expertise and skills, leadership and motivation necessary to successfully conduct and oversee health research projects in West Africa. He has a broad background in molecular biology and genomics with application in infectious diseases, including malaria, Lassa fever, Ebola virus disease and HIV. Of his career accomplishments to date, the most meaningful was my use of genomics technologies for early diagnosis and confirmation (within 6 hours) of Ebola virus disease (EVD) in Nigeria. This singular action was major in containing EVD in Nigeria, and therefore saving millions of lives in Africa. Thi...
Source: Videocast - All Events - July 19, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Could AI detect and prevent the next disease outbreak?
Training machine learning on the data amassed by the Illinois Department of Public Health could help the department better understand who might be at greatest risk of a variety of conditions, says IDPH Director Dr. Sameer Vohra. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - June 8, 2023 Category: Information Technology Source Type: video
IIG Seminar - IL-15-induced bystander T cell activation in human viral disease.
Dr. Eui-Cheol Shin investigates mechanisms of immunopathogenesis, immunosenescence, T-cell exhaustion, and human immune monitoring. Dr. Shin and his team have extensively demonstrated the pathological significance of bystander T cell activation in human disease by studying T cell responses in patients infected with viral diseases. His group has found that pre-existing bystander memory CD8+ T cells are unexpectedly activated by cytokines (e.g., IL-15) regardless of their antigen specificity, causing liver cell damage through NKG2D-mediated cytotoxicity. In characterizing IL-15-responsive bystander T cells in the liver micro...
Source: Videocast - All Events - May 11, 2023 Category: General Medicine Tags: Upcoming Events Source Type: video
Coral reef near South Pacific island of Moorea in French Polynesia
This coral reef near the South Pacific island of Moorea in French Polynesia is part of a larger reef system in the NSF Moorea Coral Reef Long-Term Ecological Research site. Here, scientists monitor the corals’ response to environmental stressors like marine heat waves and virus outbreaks, which can ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - April 21, 2023 Category: Science Source Type: video
NIH Director's Seminar Series: The ecology of emerging coronaviruses, from host reservoir to disease
In the past two decades, three coronaviruses have emerged and caused widespread outbreaks in humans. The origin of these zoonotic viruses has been traced back to bats as natural reservoir. Since the SARS epidemic in 2002 – 2003, the appreciation of bats as key hosts of zoonotic coronaviruses has advanced rapidly, but data underlying key drivers of the epidemic and pandemic emergence of these viruses remain limited. Here we discuss the emergence of MERS-CoV and SARS-CoV-2. Highlighting the origin, genetic diversity, pandemic potential, transmission dynamics, pathogenicity, and development of countermeasure against these b...
Source: Videocast - All Events - July 6, 2022 Category: General Medicine Tags: Upcoming Events Source Type: video
Socio-Cultural Responses within India during Times of Pandemic Disease
Focusing on the history of India, Dr. Mathew will explore the complex and underappreciated ways in which Indian folk-beliefs, myth, superstition, related stories (witnessed and fictional) and local traditions, have combined to inform the experience of epidemic and pandemic disease, including in the main, but not limited to, cholera, plague, influenza and COVID-19. Drawing on collections of the NLM and other institutions, he will investigate how these complex belief systems intersect with different kinds of information about these diseases, revealing how every new outbreak is accompanied with information that did not exist ...
Source: Videocast - All Events - December 23, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Outbreak Preemption and Response in the Genomic and Information Age
COVID-19 Scientific Interest Group
Dr. Sabeti is a professor at Harvard University and at Harvard T.H. Chan School of Public Health, as well as a Howard Hughes Medical Institute Investigator and member of the Broad Institute of MIT and Harvard. Her lab's research areas include: developing analytical methods to detect and investigate evolution in the genomes of humans and other species; examining host and viral genetic factors driving disease susceptibility to the devastating and deadly diseases; investigating the genomes of microbes; and determining the microbial cause of undiagnosed acute febrile illness. Just as COVID-19...
Source: Videocast - All Events - June 1, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Outbreak Response in the Genomic and Information Age
Sabeti is a computational geneticist whose lab develops powerful methods and tools for advancing genome biology and medicine. She has created some of the most widely used algorithms to mine our genome for instances of human adaptation, and created powerful molecular tools to elucidate their underlying biology. She has contributed to widely varying fields — such as viral sequencing, information theory, rural disease surveillance, and education efforts in West Africa — to create comprehensive approaches for detecting, containing, and treating deadly infectious diseases.For more information go tohttps://oir.nih.gov/sigs/c...
Source: Videocast - All Events - April 30, 2021 Category: General Medicine Tags: Upcoming Events Source Type: video
Coping with the Mental Health Effects of COVID-19
NIH is striving to combat the COVID-19 pandemic through a multifaceted approach, by supporting groundbreaking science and research and by promoting the health and safety of NIH staff. This includes ensuring the resources and support needed to manage stress and promote mental health are available. To support this effort, NIH presented this lecture on coping with the mental health effects of the COVID-19 pandemic by Dr. George Everly, Ph.D., followed by a conversation with NIH Director, Dr. Francis Collins.
More information on mental health and coping with COVID-19 is available from the following federal agencies:
CDC: Me...
Source: Videocast - All Events - August 24, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
NIH COVID-19 Lecture: COVID-19 Autopsy Findings: A Joint Effort Between NYU Winthrop Hospital and NCI — What Have We Learned So Far
NIH COVID-19 Lecture Series
Since the outbreak of COVID-19 disease, caused by SARS-CoV-2 infection, many studies focusing on clinical course, outcome, clinical parameters, prognostic markers, treatment strategies have been published. Although most patients experience mild symptoms, some have serious complications — including diffuse alveolar damage, hemodynamic shock, acute kidney failure, cardiac injury, and arrhythmia — that contribute to the high mortality rate. Autopsies can offer a better understanding of the underlying pathophysiology. Unfortunately few autopsies were performed early in the pandemic because of th...
Source: Videocast - All Events - July 20, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
COVID-19 Lecture: High Seroprevalence, Drastic Decline of Incidence and Low Infection Fatality Rate of SARS-CoV-2 Infections in Children and Adults in the Ski Resort Ischgl, Austria
NIH COVID-19 Scientific Interest Group
In early March 2020, a SARS-CoV-2 outbreak at a ski resort in Ischgl, Austria, initiated the spread of SARS-CoV-2 throughout Austria and Northern Europe. Thousands of infections can be traced back to Ischgl. In a recent study by Medical University of Innsbruck investigators, 42.4 percent of those living in Ischgl were shown to be carrying the new coronavirus antibodies, indicating they had been infected in the COVID-19 pandemic. Between April 21 and 27, a cross-sectional epidemiologic study targeting the full population of Ischgl (n= app. 1,867), of which 79 percent could be included ...
Source: Videocast - All Events - June 29, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
COVID-19: the Australian Experience and a Perspective Through a SARS-1 Lens
NIH COVID-19 SIG Lecture Series
In a few short months, SARS-CoV-2 has swept through the world infecting more than 7 million people and causing more than 400,000 deaths. However, the pandemic experience and response in different countries around the world has varied. The peak of the outbreak has passed in Australia, with more than 7,000 cases and more than 100 deaths, but there is a real possibility of a second wave of infection. The viruses that caused the SARS outbreak of 2002/2003 and the current COVID-19 pandemic are related betacoronaviruses. Experience with SARS-1 provides some insights into the COVID-19 pandemic. In ...
Source: Videocast - All Events - June 15, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
AI in the Age of COVID-19: Computational Tools for the Classification, Prediction, and Characterization of a Pandemic
Traditional methods of epidemic modeling continue to be used fruitfully for characterizing outbreaks and predicting the spread of disease in populations. However, these methods, typically relying on what are known as “ compartment models ” , require assumptions that are not necessarily sensitive to the ever-changing environmental, behavioral, temporospatial, and social phenomena that influence disease spread. However, compartment models can be enriched by the judicious use of robust methods drawn from the field of artificial intelligence that allow us to model more accurately and more quickly the population and disease...
Source: Videocast - All Events - June 5, 2020 Category: General Medicine Tags: Upcoming Events Source Type: video
National study of how Americans perceived and reacted in the first few weeks of the pandemic
This national study of more than 6,000 Americans examines the emotional, cognitive, and behavioral responses to the COVID-19 outbreak and how these early responses shape outcomes over time. The scientists are examining how widespread media coverage of the COVID-19 outbreak is associated with acute ...This is an NSF Multimedia Gallery item. (Source: NSF Multimedia Gallery)
Source: NSF Multimedia Gallery - June 4, 2020 Category: Science Source Type: video
Cotiviti creates COVID-19 Outbreak Tracker to hone in on hotspots
Cotiviti President and CEO Emad Rizk, MD, discusses how his company leverages claims and clinical data for payers to use and share with providers. (Source: Healthcare ITNews Videos)
Source: Healthcare ITNews Videos - May 29, 2020 Category: Information Technology Tags: HIMSS20 Digital Coverage Population Health Source Type: video
