The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research

The Differentiation Between Infection and Acute Charcot
Orthop Clin North Am. 2024 Apr;55(2):299-309. doi: 10.1016/j.ocl.2023.08.002. Epub 2023 Sep 7.ABSTRACTThe differentiation between acute Charcot neuroarthropathy and infection in the foot and ankle should be supported by multiple criteria. A detailed history and physical examination should always be completed. Plain radiographs should be performed, though advanced imaging, currently MRI, is more helpful in diagnosis. Scintigraphy and PET may become the standard imaging modalities once they are more clinically available due to their reported increased accuracy. Laboratory analysis can also act as a helpful diagnostic tool. H...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Ryan G Rogero Samhita Swamy Clayton C Bettin Source Type: research

Sequestration and Involucrum: Understanding Bone Necrosis and Revascularization in Pediatric Orthopedics
Orthop Clin North Am. 2024 Apr;55(2):233-246. doi: 10.1016/j.ocl.2023.09.005. Epub 2023 Oct 17.ABSTRACTSequestration, a condition where a section of bone becomes necrotic due to a loss of vascularity or thrombosis, can be a challenging complication of osteomyelitis. This review explores the pathophysiology of sequestration, highlighting the role of the periosteum in forming involucrum and creeping substitution which facilitate revascularization and bone formation. The authors also discuss the induced membrane technique, a two-stage surgical procedure for cases of failed healing of sequestration. Future directions include t...
Source: The Orthopedic Clinics of North America - February 25, 2024 Category: Orthopaedics Authors: Katherine S Hajdu Courtney E Baker Stephanie N Moore-Lotridge Jonathan G Schoenecker Source Type: research