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Fight Aging! Newsletter, May 3rd 2021
Fight Aging! publishes news and commentary relevant to the goal of ending all age-related disease, to be achieved by bringing the mechanisms of aging under the control of modern medicine. This weekly newsletter is sent to thousands of interested subscribers. To subscribe or unsubscribe from the newsletter, please visit: https://www.fightaging.org/newsletter/ Longevity Industry Consulting Services Reason, the founder of Fight Aging! and Repair Biotechnologies, offers strategic consulting services to investors, entrepreneurs, and others interested in the longevity industry and its complexities. To find out m...
Source: Fight Aging! - May 2, 2021 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Reviewing Myostatin in Muscle Growth, and Efforts to Produce Myostatin-Targeted Therapies
Myostatin is one of the better targets for enhancement therapies from the point of view of feasibility and existing data on its effects. Myostatin suppresses muscle growth via intracellular signaling. A range of possible methods exist to interfere in this process, some of which have been trialed in human patients: reducing production of myostatin, binding to circulating myostatin with antibodies to ensure clearance, preventing myostatin from binding to cell surface receptors in other ways, upregulation of follistatin, an antagonist to myostatin, and so forth. Myostatin loss of function mutants, natural and artificial, exis...
Source: Fight Aging! - April 28, 2021 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Funtabulously Frivolous Friday Five 289
Dr Mark Corden Funtabulously Frivolous Friday Five 289 It's Friday. Boggle your brain with FFFF challenge and some old fashioned trivia. Funtabulously Frivolous Friday Five 289 (Source: Life in the Fast Lane)
Source: Life in the Fast Lane - August 9, 2019 Category: Emergency Medicine Authors: Dr Mark Corden Tags: FFFF Aspiration blue sclera Children choking coughing FB febrile convulsions Foreign Body head trauma Human saliva kids osteogenesis imperfecta Paediatrics pediatrics roseola vomiting wheezing Source Type: blogs

Double Trouble: Both-Bone Fractures
​Both-bone forearm fractures may make you feel a little nervous. A completely crooked forearm is definitely a disturbing sight. Both-bone forearm fractures (especially of the midshaft) typically require surgical intervention, but relocation of bony injuries, regardless of site or complexity, is an important and necessary skill you need to know. Plus, you will be required to assist with sedation, reduction, and splinting when the orthopedic team is involved.​Correcting and stabilizing two bones (instead of one) may seem tricky, but we are going to help you do it right. This complex procedure should be done with orthoped...
Source: The Procedural Pause - August 31, 2018 Category: Emergency Medicine Tags: Blog Posts Source Type: blogs

Exercise: Can a few minutes a day keep a hip fracture away?
This study is so important because it really gives all of us such a reasonable goal. Can we give it our strongest effort for one to two minutes a day? I think we can. It also shows that if we make a small, measurable, but regular change, we can all dance, run, jog, jump, or hop our way to better health! The post Exercise: Can a few minutes a day keep a hip fracture away? appeared first on Harvard Health Blog. (Source: Harvard Health Blog)
Source: Harvard Health Blog - October 12, 2017 Category: Consumer Health News Authors: Nandini Mani, MD Tags: Exercise and Fitness Health Osteoporosis bone health brittle bones Source Type: blogs

Research and Reviews in the Fastlane 160
Welcome to the 160th edition of Research and Reviews in the Fastlane. R&R in the Fastlane is a free resource that harnesses the power of social media to allow some of the best and brightest emergency medicine and critical care clinicians from all over the world tell us what they think is worth reading from the published literature. This edition contains 5 recommended reads. The R&R Editorial Team includes Jeremy Fried, Nudrat Rashid, Soren Rudolph, Justin Morgenstern and, of course, Chris Nickson. Find more R&R in the Fastlane reviews in the R&R Archive, read more about the R&R project or check o...
Source: Life in the Fast Lane - November 16, 2016 Category: Emergency Medicine Authors: Jeremy Fried Tags: Emergency Medicine Intensive Care R&R in the FASTLANE Resuscitation EBM Education literature recommendations research and reviews Source Type: blogs

A Tour of OrthoPediatrics: The World ’s Only Company Dedicated to Orthopedic Implants for Kids
On our recent tour of the medical device space in Northeast Indiana, we stopped off at OrthoPediatrics, a company that’s literally reshaping the lives of children for the better. It was founded in 2006 as the only company in the world to be exclusively devoted to pediatric orthopedics. Since then it has developed a series of products for spinal correction, long bone trauma and deformity, and for ACL reconstruction. OrthoPediatrics designs devices that are not only scaled down in size from adult orthopedic implants, but are specifically tuned to the requirements of little patients and their surgeons. For example, most...
Source: Medgadget - November 1, 2016 Category: Medical Equipment Authors: Editors Tags: Exclusive Orthopedic Surgery Source Type: blogs

Osteogenesis Imperfecta: Radio-Orthopedic Correlation Video
Osteogenesis imperfecta also known as brittle bone disease or Lobstein syndrome, is a congenital bone disorder characterized by brittle bones that are prone to fracture. Most cases are caused by mutations in the COL1A1 and COL1A2 genes, both of which code for type I collagen.Here is a teaching Video:Famous Radiology Blog http://www.sumerdoc.blogspot.com TeleRad Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - September 14, 2016 Category: Radiology Authors: Sumer Sethi Source Type: blogs

When practicing medicine, hold on to what makes you whole
Blackness covers the paper in its entirety. Hunched over, charcoal stained fingertips splayed out in front of me, I exhale and my saturated breath evokes miniature tornadoes. The fragrance of warm charcoal engulfs my olfactory bulb and my temporal lobe explodes with images of the past. I am transported back to scraped shins guarded by starched, white ruffled socks. My fingertips awaken with the memory of smeared purple chalk on warm summer cement and the velvety caress of red and yellow tulips. I am home again, where the earthy scent of newly piled mulch mingles with the syrupy sweetness of golden honey suckles. Once more ...
Source: Kevin, M.D. - Medical Weblog - August 1, 2015 Category: Journals (General) Authors: Tags: Education Residency Source Type: blogs

Who is perfect? Advocacy ads for real people.
What is the nature of disability? What is the nature of beauty? What is perfection? Who among us is perfect? These questions are at the heart (literally and figuratively) of a project undertaken by Pro Infirmis, a Switzerland-based advocacy organization raising awareness of people with disabilities, promoting the International Day of Persons with Disabilities in December 2013. Mannequins in fashionable shops on Zurich’s tony street the Bahnhofstrasse were replaced by new ones, artfully, painstakingly and lovingly created, as shown in the video. Pro Infirmis’s website tells us “who” we are looking at in human and 3-...
Source: Disruptive Women in Health Care - January 22, 2015 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: Advocacy Body Image Consumer Health Care Disabilities Social Media Source Type: blogs

Five Month-Old Baby Dies Just Days After 8 Vaccinations – Parents Are Charged With Her Murder
Conclusion As with so many of these cases, Baby A did not just receive just one vaccine, so it is therefore difficult to pinpoint exactly which vaccine, if any, may have led to her death. However, it is vital that the doctors involved in this case as with all cases, consider the vaccines as a possible contributory factor. Sadly, these parents have been accused and charged with the murder of their daughter without any substantial evidence of foul play. There appears to be no evidence of external head injuries or bruising to the upper body to indicate that Baby A had been shaken. I believe that if this child had been shaken ...
Source: vactruth.com - August 17, 2013 Category: Health Medicine and Bioethics Commentators Authors: Christina England Tags: Christina England Top Stories Adverse Reaction Dr. Viera Schreibner Prevenar shaken baby syndrome Vaccine Adverse Event Reporting System (VAERS) Vaccine Death Source Type: blogs

Wormian Bones-Causes
Intrasutural ossicles in lambdoid, posterior sagittal, temporosquamosal sutures; normal up to 6 months of age Mnemonic: PORK CHOPS  Pyknodysostosis Osteogenesis imperfecta Rickets in healing phase Kinky hair syndrome Cleidocranial dysostosis Hypothyroidism / Hypophosphatasia Oto-palato-digital syndrome Primary acroosteolysis (Hajdu-Cheney) / Pachydermoperiostosis / Progeria Syndrome of Down From Sumer's Radiology Site http://www.sumerdoc.blogspot.com -The Top Radiology Magazine. Teleradiology Providers at www.teleradproviders.com Mail us at sales@teleradproviders.com (Source: Sumer's Radiology Site)
Source: Sumer's Radiology Site - April 19, 2013 Category: Radiologists Authors: Sumer Sethi Source Type: blogs

USMLE Questions – Characteristic Disease Findings
The United States Medical Licensing Examination (USMLE) is designed to emphasize knowledge of clinical scenarios and clinical pearls, even on Step I. Listed below are some commonly encountered disease findings and characteristics. Feature Disease 45, X chromosome Turner’s syndrome 5-HIAA increased in urine Carcinoid syndrome Aganglionic rectum Hirschsrpung’s disease Apple-core sign on barium enema Colon cancer Arched back (opisthotonos) Tetanus Argyll-Robertson pupil Syphilis Ash leaf on forehead Tuberous sclerosis Auer rods  Acute myelogenous leukemia Austin Flint murmur Aortic regurgitation...
Source: Inside Surgery - January 18, 2013 Category: Surgeons Authors: Editor Tags: Surgpedia USMLE diseases findings VMA water hammer pulse Source Type: blogs