The clinical trial of alternative relugolix administration for uterine leiomyoma prior to surgically treatment: a study protocol for Non-Adverse Relugolix Administration (NARA) trial
This study aims to prove both the non-inferiority in leiomyoma volume reduction and superiority in adverse effects occurrence reduction, which will provide a novel method to escape adverse effects while maintaining the effect of leiomyoma reduction.Trial registrationJapan Registry of Clinical Trials jRCTs051230078. Registered on 26 July 2023. (Source: Trials)
Source: Trials - January 19, 2024 Category: Research Source Type: clinical trials
Broad-spectrum antibiotic prophylaxis in tumor and infected orthopedic surgery —the prospective-randomized, microbiologist-blinded, stratified, superiority trials: BAPTIST Trials
DiscussionIn selected patients with a high risk for infections due to selection of prophylaxis-resistant SSI, a broad-spectrum combination with vancomycin and gentamycin might prevent SSIs (and other postoperative infections) better than the prophylaxis with cefuroxime.Trial registrationClinicalTrial.gov NCT05502380. Registered on 12 August 2022. Protocol version: 2 (3 June 2022) (Source: Trials)
Source: Trials - January 19, 2024 Category: Research Source Type: clinical trials
The Efficacy of Music in Preventing Delirium in Elderly Patients With Hip Fracture: A Randomized Controlled Trial
Conditions: Delirium in Old Age; Hip Fractures Interventions: Procedure: experimental group Sponsors: Chang Gung Memorial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Intramedullary Headless Screw Fixation for Metacarpal and Phalangeal Fractures
Conditions: Metacarpal Fracture; Phalanx Fracture Interventions: Procedure: Intramedullary headless screw fixation Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
The Efficacy of Music in Preventing Delirium in Elderly Patients With Hip Fracture
Conditions: Delirium in Old Age; Hip Fractures Interventions: Procedure: experimental group Sponsors: Chang Gung Memorial Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Testing Implementation of Total Joint Replacement Rehabilitation Quality Indicator Toolkits
Conditions: Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee Interventions: Other: QI toolkit implementation Sponsors: University of British Columbia; The Arthritis Society, Canada; Centre for Aging SMART; Centre for Advancing Health Outcomes Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Cast Immobilization Versus Percutaneous Pinning for Fracture of Radius in an Elderly Patient
Conditions: Closed Fracture of Lower End of Radius Interventions: Procedure: Percutaneous pinning; Procedure: Cast immobilization Sponsors: Queen Savang Vadhana Memorial Hospital, Thailand Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Management Of Patellar Fractures By Craniofacial Mesh Plate Osteosynthesis Augmented by Screws
Conditions: Patella Fracture Interventions: Procedure: fixation of patella fractures by craniofacial mesh plate osteosynthesis augmented by screws Sponsors: Sohag University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 15, 2024 Category: Research Source Type: clinical trials
Nirvana Super Pro Supplementation in Orthopedic Surgery Patients
Conditions: Arthropathy of Knee; Arthropathy of Hip Interventions: Dietary Supplement: Supplementation with Nirvana Super Pro Liquid Supplements; Dietary Supplement: Non-Supplementation Group Sponsors: Super Inspired LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials
Prophylactic Radiotherapy Of MInimally Symptomatic Spinal Disease (PROMISSeD): study protocol for a randomized controlled trial
DiscussionThe results of this RCT will demonstrate the value, if any, of early radiotherapy for high-risk spine metastases. The trial has received IRB approval, funding, and prospective registration (NCT05534321) and has been open to accrual since August 19, 2022. If positive, the trial will expand the scope and utility of spine radiotherapy.Trial registrationClinicalTrials.GovNCT05534321. Registered September 9, 2022.Trial statusVersion 2.0 of the protocol (2021-KOT-002), revised last on September 2, 2022, was approved by the WCG institutional review board (Study Number 1337188, IRB tracking number 20223735). The trial wa...
Source: Trials - January 12, 2024 Category: Research Source Type: clinical trials
Low-Dose Short-Term Ketorolac to Reduce Chronic Opioid Use in Orthopaedic Polytrauma Patients
Conditions: Orthopaedic Polytrauma; Chronic Opioid Use Interventions: Drug: Ketorolac Injection; Other: Normal Saline Sponsors: Massachusetts General Hospital; United States Department of Defense Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Effectiveness of Erector Spinae Plane Block for Percutaneous Arthrodesis of Spinal Fractures
Conditions: SPINAL Fracture; Pain, Postoperative Interventions: Procedure: Erector spinae plane block with naropeine [3,75 mg/mL]; Procedure: ESPB with saline 0,9% Sponsors: University Hospital, Lille Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Antibiotic-Loaded Cement Versus Non-Antibiotic-Loaded Cement in Hip Prosthesis Surgery for Proximal Femur Fractures
Conditions: Proximal Femoral Fractures Interventions: Drug: Antibiotic loaded; Other: Placebo Sponsors: Universit à Vita-Salute San Raffaele Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 11, 2024 Category: Research Source Type: clinical trials
Effects of PNF Technique in Children With Post Fracture Elbow Stiffness
Conditions: Fracture Interventions: Other: proprioception neuromuscular facilitation technique Sponsors: Riphah International University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 10, 2024 Category: Research Source Type: clinical trials
Randomized Controlled Clinical Trial of Internal Fixation of Intertrochanteric Fractures of Femur Guided by Conventional Versus IF-AI Artificial Intelligence Program
Conditions: Hip Fractures Interventions: Procedure: Surgical protocol guided by artificial intelligence software Sponsors: Peking University Third Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 8, 2024 Category: Research Source Type: clinical trials
