Fight Aging! Newsletter, March 27th 2017
In conclusion, DNAm of multiple disease-related genes are strongly linked to mortality outcomes.
The recently established epigenetic clock (DNAm age) has received growing attention as an increasing number of studies have uncovered it to be a proxy of biological ageing and thus potentially providing a measure for assessing health and mortality. Intriguingly, we targeted mortality-related DNAm changes and did not find any overlap with previously established CpGs that are used to determine the DNAm age. Our findings are in line with evidence, suggesting that DNAm involved in ageing or health-related outcomes are mostly...
Source: Fight Aging! - March 26, 2017 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
A 7-Pound Premature Baby Died After Receiving 8 Vaccine Doses, Her Death Was Blamed On Co-Sleeping Instead Of The Toxic Vaccines
Conclusion
Medical examiners are putting the blame on parents for co-sleeping, while completely ignoring the vaccines given to the child hours or days before, when investigating these infant deaths. They will also relate an infant’s death to poisoning of the body due to something the child ingested or inhaled, but not from the poisons injected through the vaccines. [29]
In the state of Louisiana, health officials have been applauded for having fairly high vaccination rates, but at the same time, Louisiana has consistently been ranked one of the worst states in the nation for having high infant mortality rates, but nowher...
Source: vactruth.com - January 19, 2017 Category: Allergy & Immunology Authors: Augustina Ursino Tags: Augustina Ursino Case Reports on Vaccine Injury Human Recent Articles Top Picks Top Stories Aysia Hope Clark Lafayette General Medical Center National Vaccine Injury Compensation Program Recombivax Source Type: blogs
Looking Back and Ahead in the Use of Pluripotent Stem Cells in Medicine
There are a few papers and commentaries that you might find interesting in the latest issue of Regenerative Medicine. The one I'll point out here offers a retrospective and a forecast for the use of pluripotent stem cells in medicine. It is authored by one of the more outspoken figures from the last decade of research and development, but is worth reading regardless of that point. All industries tend to follow what has come to be known as a hype cycle as they reach critical mass and transition into broad adoption and large scale development. Stem cell medicine as a whole had its initial peak of attention and overhyped expe...
Source: Fight Aging! - December 15, 2016 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs
A Reasonable Perspective on Cryonics
In this article, one of the scientists involved in our rejuvenation research community outlines a very reasonable view on cryonics and cryopreservation. Cryonics is the low-temperature preservation of at least the brain following death, done these days with the use of cryoprotectants and vitrifiction to minimize ice crystal formation. It offers an unknown chance at a future restoration to life: technology marches onwards year after year, and for so long as the structures that encode the data of the mind are preserved, there is the possibility of living again in a future age that has mastered the technologies needed for res...
Source: Fight Aging! - December 2, 2016 Category: Research Authors: Reason Tags: Daily News Source Type: blogs
Fight Aging! Newsletter, September 26th 2016
This study included 647 patients 80 to 106 years of age who had audiometric evaluations at an academic medical center (141 had multiple audiograms). The degree of hearing loss was compared across the following age brackets: 80 to 84 years, 85 to 89 years, 90 to 94 years, and 95 years and older. From an individual perspective, the rate of hearing decrease between 2 audiograms was compared with age. The researchers found that changes in hearing among age brackets were higher during the 10th decade of life than the 9th decade at all frequencies for all the patients (average age, 90 years). Correspondingly, the annual rate of ...
Source: Fight Aging! - September 25, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Fight Aging! Newsletter, August 22nd 2016
This study provides additional fuel to really bolster research efforts by us and others in geroscience, a field that seeks to understand relationships between the biology of aging and age-related diseases. Aging is the most important risk factor for common chronic conditions such as heart disease, Alzheimer's and cancer, which are likely to share pathways with aging and therefore interventions designed to slow biological aging processes may also delay the onset of disease and disability, thus expanding years of healthy and independent lives for our seniors."
Longer-Lived Parents and Cardiovascular Outcomes
...
Source: Fight Aging! - August 21, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
It ’ s Happening; Unintended Consequences of “ Quality ”
Once again, I called it!
Some of my previous takes on the fallacies of “Quality”:
9/24/09:
The biggest mistake made by Medicare, private insurers, and other entities seeking to improve medical care by rewarding “quality” is mistaking it for “performance”.
2/18/13:
The real reason doctors have begun “requiring” that patients undergo all manner of screening interventions is to enhance their compliance ratios. After all, the quickest way to get to 100% is to get rid of everyone who falls short.
Now it’s moved to hospitals:
Hospitals are throwing out organs and denying transplants to meet federal ...
Source: Musings of a Dinosaur - August 12, 2016 Category: Primary Care Authors: notdeaddinosaur Tags: Medical Source Type: blogs
Not Your Typical Health Conference: Takeaways From Spotlight Health
For the second year, a small Health Affairs team attended Spotlight Health in beautiful Aspen, Colorado. With life-sized scrabble games and lemonade stands by Jack, Spotlight Health is different from your typical health conference. This year’s topics also went beyond typical — opioids, planetary health, healthy eating, gender, and child development were some of the issues covered in sessions.
Here are a few of the ideas we heard that are worth sharing.
1. Curbing the Opioid Epidemic
The opioid crisis is disproportionately affecting those in rural areas. The US Department of Agriculture (yes, you read that right) i...
Source: Health Affairs Blog - July 7, 2016 Category: Health Management Authors: Rachel Dolan Tags: Costs and Spending Drugs and Medical Technology Equity and Disparities Featured Global Health Population Health Public Health Access big data Contraception opioid epidemic Pharma Source Type: blogs
Fight Aging! Newsletter, June 20th 2016
We examined the engraftment and differentiation of alkaline phosphatase-positive NSCs expanded from the postnatal subventricular zone (SVZ), 3 months after grafting into the intact young or aged rat hippocampus. Graft-derived cells engrafted robustly into both young and aged hippocampi. Although most graft-derived cells pervasively migrated into different hippocampal layers, the graft cores endured and contained graft-derived neurons.
The results demonstrate that advanced age of the host at the time of grafting has no major adverse effects on engraftment, migration, and differentiation of grafted subventricular zone...
Source: Fight Aging! - June 19, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
New Organ and Organ Preservation Alliance Announce the Vascular Tissue Challenge and Other Initiatives in Organ Engineering
The US government is beginning to make more of an overt show of supporting tissue engineering, cryobiology, and other areas that can help move the needle in the field of organ transplantation, as demonstrated by today's White House Organ Summit. It will take some time to see how this pans out; typically the immediate outcome of this sort of public-private partnership is that it becomes easier for private and philanthropic initiatives at the cutting edge to raise funds for projects that can advance the state of the art. Familiarity with the field and its goals spreads, and that helps, as fundraising is always slower when yo...
Source: Fight Aging! - June 13, 2016 Category: Research Authors: Reason Tags: Activism, Advocacy and Education Source Type: blogs
Fight Aging! Newsletter, May 9th 2016
This report is comprehensive and interested readers are encouraged to review. The authors provided projections on organ donation and transplantation rates, quality-adjusted life years and life years saved, health risks to patients, living organ donation, cross-border exchange, and health inequalities. Their most favorable scenario projected health benefits including transplanting up to 21,000 more organs annually in the EU, which would save 230,000 life years or gain 219,000 quality-adjusted life years (QALYs). For social impacts, it was predicted that increasing organ transplantation will have a positive effect on quality...
Source: Fight Aging! - May 8, 2016 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs
Why I’m doing one of the riskiest surgeries in medicine
If the act of organ donation is among humanity’s greatest gifts, what can be said of living donors who undergo surgery to extend and improve the life of another? It’s truly a courageous and inspiring sacrifice.
I was honored recently to be able to perform my first living-donor liver transplant. Jason Clark, 28, donated about 60 percent of his liver to his father, Lynn, 57, who had been sick for many years after contracting Hepatitis C from a blood transfusion following a car accident in 1980. Lynn was in end-stage liver failure and yet was nowhere near the top of the waitlist. The people closest to Lynn watched helples...
Source: Kevin, M.D. - Medical Weblog - May 4, 2016 Category: Journals (General) Authors: Robin Kim, MD Tags: Physician Surgery Source Type: blogs
Views of the Cost and Time Required to Build an Organ Engineering Industry
This report is comprehensive and interested readers are encouraged to review. The authors provided projections on organ donation and transplantation rates, quality-adjusted life years and life years saved, health risks to patients, living organ donation, cross-border exchange, and health inequalities. Their most favorable scenario projected health benefits including transplanting up to 21,000 more organs annually in the EU, which would save 230,000 life years or gain 219,000 quality-adjusted life years (QALYs). For social impacts, it was predicted that increasing organ transplantation will have a positive effect on quality...
Source: Fight Aging! - May 4, 2016 Category: Research Authors: Reason Tags: Of Interest Source Type: blogs
TBT: February Man of the Month: Dan Miller
April is National Donate Life Month (NDLM) an entire month of local, regional and national activities dedicated to help encourage Americans to register as organ, eye and tissue donors and to celebrate those that have saved lives through the gift of donation. In honor of NDLM for today’s TBT post we couldn’t think of a more appropriate post than the one highlighting the selflessness of our February Man of the Month.
On the topic of organ donation, Dan Miller had a consistent message: “Do the research.”
For Dan, a healthy, 20-year-old junior at James Madison University in Harrisonburg, Va., this meant seekin...
Source: Disruptive Women in Health Care - April 28, 2016 Category: Consumer Health News Authors: dw at disruptivewomen.net Tags: TBT Source Type: blogs
Oregon Cryonics, a New US Cryonics Provider
Cryonics is the low-temperature preservation of the recently deceased, with the aim of preserving the fine structure of the brain, and thus the data of the mind, for a future in which advanced technology will allow for a return to active life. The odds of success are unknown, but certainly infinitely greater than the zero odds offered by all of the present alternatives. Billions will die from old age before the earliest possible date on which the first complete set of robust rejuvenation therapies will become widespread. Are we really to write them off? I would like to think that we can do better than that - and hence the ...
Source: Fight Aging! - February 17, 2016 Category: Research Authors: Reason Tags: Healthy Life Extension Community Source Type: blogs
