TWiV 1006: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses immunogenicity and tolerability of a bivalent virus-like particle norovirus vaccine candidate in children from 6 months up to 4 years of age, influenza hemagglutinin stem nanoparticle vaccine induces cross-group 1 neutralizing antibodies in healthy adults, COVID-19 surveillance after expiration of the public health emergency declaration, provisional mortality data, targeted vaccine messaging to promote COVID-19 vaccines for children and youth, vaccines and related biological products advisory committee meeting June 15, 2023 announcement, how to overhaul the CDC, impact o...
Source: This Week in Virology - MP3 Edition - May 13, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 996: Clinical update with Dr. Daniel Griffin
In his weekly clinical update, Dr. Griffin discusses how antibiotics don’t reduce risk of death from viral respiratory infections, norovirus infections continue to rise in the US, ABO blood types and SARS-CoV-2 infection assessed using seroprevalence data in a large population-based sample, maternal third dose of BNT162b2 mRNA vaccine and risk of infant COVID-19 hospitalization, association of treatment with Nirmatrelvir and the risk of Post–COVID-19 condition, mechanically ventilated patients with COVID-19 had a higher chance of in-hospital death if treated with high-flow nasal cannula oxygen before intubation, high-f...
Source: This Week in Virology - MP3 Edition - April 1, 2023 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Public Health with Laurie Garrett: Wastewater Testing
Laurie Garrett discusses the role of wastewater testing in public health and her idea of a device that could be used by anyone to analyze water samples. This podcast is not an episode of TWiV, but I thought it would be of interest to listeners. Laurie Garrett and Vincent Racaniello Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode Support MicrobeTV with a Spike t-shirt (Vaccinated.us) Coliform testing of water in Florida (YouTube) Declining cost of genome sequencing (Illumina) National wastewater surveillance system (CDC) Advances in detection of viruses in...
Source: This Week in Virology - MP3 Edition - October 4, 2022 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

Norovirus could spread through saliva: a new route for infection?
00:47 Enteric viruses may spread through salivaEnteric viruses, such as norovirus, cause a significant health burden around the world and are generally considered to only spread via the faecal-oral route. However, new research in mice suggests that saliva may also be a route of transmission for these viruses, which the authors say could have important public health implications.Research Article: Ghosh et al.08:59 Research HighlightsHow devouring space rocks helped Jupiter to get so big, and what analysing teeth has revealed about the diet of the extinct super-sized megalodon shark.Research Highlight: The heavy diet that ma...
Source: Nature Podcast - June 29, 2022 Category: Science Authors: Springer Nature Limited Source Type: podcasts

"Going Viral" -- The Discovery Files
Norovirus causes 20 million cases of food poisoning in the US every year. Now, a smartphone can easily detect this gut-busting microbe -- hopefully before it gets you. (Source: The Discovery Files)
Source: The Discovery Files - September 9, 2019 Category: Science Authors: National Science Foundation Source Type: podcasts

TWiV 493: Condit is on drugs and norovirus is lit
The TWiVerati discuss the FDA Advisory Committee deliberation on the anti-poxvirus drug tecovirimat, and immune cells in gut-associated lymphoid tissue as the major target during acute murine norovirus infection. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine FDA meeting materials for tecovirimat(FDA) SIGA Briefing Information (pdf) Errata to the SIGA Briefing Information (pdf) Gut immune cells major targets of norovirus inf...
Source: This Week in Virology - MP3 Edition - May 13, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 492: CRISPR diagnostics
The Masters of the TWiXome review the development of sensitive, portable, and field-based viral diagnostics using the CRISPR-Cas system. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine Norovirus outbreaks from nori(Emerging Inf Dis) SHERLOCK(Science) HUDSON(Science) DETECTR(Science) Letters readon TWiV 492 Weekly Science Picks Alan - Decline of local newspapers leaves epidemiologists blind Kathy- Journal oversight, mental he...
Source: This Week in Virology - MP3 Edition - May 6, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 491: The Ileum and the Odyssey
The TWiVome deconstructs the evolutionary history of RNA viruses, and immune promortion of murine norovirus pathogenesis by replication in intestinal tuft cells. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode ASM Microbe 2018 Support Viruses & Cells Gordon Conference Faculty positions at Icahn School of Medicine Evolutionary historyof RNA viruses (Nature) The amphioxus song Norovirus tropism for tuft cells(Science) Letters readon TWiV 491 Weekly Science Picks Alan - Oligodendroglioma in song Kathy- Everything-repellent coating...
Source: This Week in Virology - MP3 Edition - April 29, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 445: A nido virology meeting
From Nido2017 in Kansas City, Vincent  meets up with three virologists to talk about their careers and their work on nidoviruses.Host:  Vincent RacanielloGuests:  Margo Brinton,Luis Enjuanes, andLinda SaifBecome a  patron of TWiV!Links for this episodeMurine flavivirusresistance gene (PNAS)TIA-1/TIAR binding sites in West Nile virus RNA (J Virol)Infectious coronavirus DNA in BAC (PNAS)Norovirus binding tolettuce (Appl Env Micro)This episode is brought to you  by Blue Apron. Blue Apron is the #1 fresh ingredient and recipe delivery service in the country. See what’s on the menu this week and get your first 3 meals ...
Source: This Week in Virology - MP3 Edition - June 11, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 406: Pow, right in the enteroids!
Hosts:  Vincent Racaniello,  Dickson Despommier,  Alan Dove,  Rich Condit, and  Kathy SpindlerThe TWiV team discussed eye infections caused by Zika virus,  failure of Culex mosquitoes to transmit the virus, and replication of norovirus in stem cell derived enteroids. Become a  patron of TWiV!Links for this episodeFlorida DOH  daily Zika updateCongress fails  again on Zika (NY Times)Culex pipiens does not support Zika virus replication (EID)Zika virus in the  eye (Cell Rep)Norovirus replication in  enteroids (Science)Norovirus replication in B cells (TWiV 312)Baylor  press releaseNorovirus replication...
Source: This Week in Virology - MP3 Edition - September 11, 2016 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 318: Last year in virology
Hosts: Vincent Racaniello, Alan Dove, Rich Condit, and Kathy Spindler The TWiV gang reviews ten fascinating, compelling, and riveting virology stories from 2014.   Ten virology stories of 2014 Ebola virus outbreak (TWiV 314, 309, 308, 307, 306, 305, 304, 303, 302, 298, 297, 283) Directional uncoating of rhinovirus RNA (TWiV 267) Pandemic pathogen controversy (TWiV 287) Viral evolution (TWiV 275) Borna virus inhibition by endogenous DNA (TWiV 303) MERS-CoV in dromedary camels (TWiV special, TWiV 287) Oncolytic...
Source: This Week in Virology - MP3 Edition - January 4, 2015 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 313: With viruses like these, who needs enemas?
Hosts: Vincent Racaniello, Alan Dove, and Rich Condit Vincent, Alan, and Rich discuss how norovirus, an enteric virus, can replace the functions of the gut microbiome. Links for this episode Ebola virus update (WHO) Norovirus can replace functions of gut microbiome (Nature) Post-vaccinal distemper encephalitis (N Z Vet J) Novel sea otter poxvirus (J Wildl Dis) Poliovirus escapes antibodies (virology blog) CDC whistleblower saga (Sci Based Med) Snopes on CDC whistleblower Image credit Letters read on TWiV 313 Video of this episode - v...
Source: This Week in Virology - MP3 Edition - November 30, 2014 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

TWiV 312: She sells B cells
Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler The TWiVbolans discuss the finding that human noroviruses, major causes of gastroenteritis, can for the first time be propagated in B cell cultures, with the help of enteric bacteria. This episode of TWiV is brought to you by the Department of Microbiology at Icahn School of Medicine at Mount Sinai. Composed of over 20 virology labs, all centralized in one building in the heart of New York City, this department is a perfect fit for anyone with an interest in pursuing virus research. The Dep...
Source: This Week in Virology - MP3 Edition - November 23, 2014 Category: Virology Authors: Vincent Racaniello Source Type: podcasts

A new way to study norovirus and a news roundup (7 November 2014)
Stephanie Karst discusses her team's successful efforts to culture norovirus in the lab and what this new system means for treatment and prevention. David Grimm brings daily news stories on counting virtual friends, drama at the center of the galaxy, and the birth of the penis. Hosted by Sarah Crespi. (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - November 7, 2014 Category: Science Authors: Science Magazine Source Type: podcasts

A new way to study norovirus and a news roundup (7 November 2014)
Stephanie Karst discusses her team's successful efforts to culture norovirus in the lab and what this new system means for treatment and prevention. David Grimm brings daily news stories on counting virtual friends, drama at the center of the galaxy, and the birth of the penis. Hosted by Sarah Crespi.   (Source: Science Magazine Podcast)
Source: Science Magazine Podcast - November 7, 2014 Category: Science Authors: Science Source Type: podcasts