Nicotine Virtual Reality Conditioned Place Preference
Conditions: Nicotine Addiction; Nicotine Use Disorder Interventions: Drug: Nicotine; Drug: Placebo oral capsule Sponsors: University of Chicago Withdrawn (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 14, 2024 Category: Research Source Type: clinical trials

Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects
Conditions: Tobacco Smoking; Tobacco Withdrawal; Nicotine Addiction; Nicotine Withdrawal; Nicotine Replacement Therapy Interventions: Drug: Bupropion Sponsors: National Institute of Respiratory Diseases, Mexico Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 12, 2024 Category: Research Source Type: clinical trials

Effects of Tobacco Cut and Nicotine Form on the Abuse Liability of Moist Snuff
Conditions: Tobacco-Related Carcinoma Interventions: Procedure: Biospecimen Collection; Procedure: Carbon Monoxide Measurement; Behavioral: Smokeless Tobacco Use; Other: Survey Administration Sponsors: Ohio State University Comprehensive Cancer Center; National Institute on Drug Abuse (NIDA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 8, 2024 Category: Research Source Type: clinical trials

$9 million NIH grant advances drug to treat nicotine addiction
SAN DIEGO, Feb. 6, 2024. Scientists at Camino Pharma, LLC, Sanford Burnham Prebys and University of California San Diego School of Medicine­­received a $9-million grant (U01DA057847) from the National Institute on Drug Abuse (NIDA) at the... (Source: Drugs.com - Clinical Trials)
Source: Drugs.com - Clinical Trials - February 6, 2024 Category: Pharmaceuticals Source Type: clinical trials

Young Adult Tobacco/Nicotine and Cannabis Co-use
Conditions: Tobacco Use Disorder; Nicotine Dependence Interventions: Behavioral: Counseling; Behavioral: Contingency management; Behavioral: Text-based support Sponsors: Medical University of South Carolina; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 2, 2024 Category: Research Source Type: clinical trials

Modeling Tobacco Regulatory Impacts in Appalachia Using the Experimental Tobacco Marketplace
Conditions: Tobacco Use; Cigarette Use Interventions: Drug: Very Low Nicotine Cigarette; Behavioral: Reduced nicotine regulatory environment; Behavioral: Restriction on characterizing flavors in combustible nicotine products; Behavioral: Restriction on characterizing flavors in noncombustible nicotine products Sponsors: Mikhail N Koffarnus; National Institute on Drug Abuse (NIDA) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 31, 2024 Category: Research Source Type: clinical trials

Menthol, Inflammation, and Nicotine Transition Study
Conditions: Cigarette Smoking; Inflammatory Response Interventions: Other: Cigarette Type Switching Sponsors: Rosalind Franklin University of Medicine and Science; National Heart, Lung, and Blood Institute (NHLBI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 30, 2024 Category: Research Source Type: clinical trials

Tobacco Treatment Comparison for Cancer Care
Conditions: Smoking Cessation; Cancer Interventions: Drug: Transdermal Nicotine Patch; Behavioral: Standard Telephone Counseling; Drug: Varenicline; Behavioral: Cancer-Targeted Telephone Counseling; Other: Mailed Information about Standard Care Resources Sponsors: University of Wisconsin, Madison; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials

Update of statistical analysis plan for: Integration of smoking cessation into standard treatment for patients receiving opioid agonist therapy who are smoking tobacco: protocol for a randomised controlled trial (ATLAS4LAR)
AbstractThis protocol paper presents an updated statistical analysis plan of the protocol of a randomised controlled trial. The randomised controlled trial investigates the effect of integrating smoking cessation interventions at outpatient opioid agonist therapy (OAT) clinics for persons with opioid dependency receiving OAT medication. The intervention group receives weekly follow-up including a short behavioural intervention and provision of nicotine replacement products. The control group receives standard treatment. The duration of the intervention is 16 weeks and the follow-up was completed by the end of October 2023....
Source: Trials - January 6, 2024 Category: Research Source Type: clinical trials

Human Laboratory Study of the Effects of Nicotine Product Claims on Appeal, Perceptions, and Use Behavior
Conditions: Behavior, Risk Interventions: Behavioral: 3x3 between-subjects experimental exposure Sponsors: Ohio State University Comprehensive Cancer Center; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 5, 2024 Category: Research Source Type: clinical trials

Clinical study protocol on electronic cigarettes and nicotine pouches for smoking cessation in Pakistan: a randomized controlled trial
DiscussionThe study will evaluate the participants at the baseline as they decide the quit date. After every 12 weeks, a follow-up survey with the participants will be conducted. Results are anticipated to inform the public, decision-makers, and researchers about the effects of using e-cigarettes and nicotine pouches in the short- and medium-term periods. Critically, the potential of e-cigarettes and other alternative nicotine delivery systems as smoking cessation aid will be assessed.Trial registration ClinicalTrials.govNCT05715164. Registered on February 6, 2023. Protocol version. Protocol version 1.0, 14-12-2022Trial in...
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials

Semaglutide for Post-Smoking Cessation Weight Management
Conditions: Obesity; Overweight; Cigarette Smoking Interventions: Drug: semaglutide 2.4mg; Drug: Placebo; Drug: Nicotine Replacement Therapy (NRT, nicotine patch); Behavioral: Brief Smoking Cessation Counseling Sponsors: The University of Texas Health Science Center, Houston Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 18, 2023 Category: Research Source Type: clinical trials

Pharmacokinetics and Comparative Bioavailability of Nicotine From Two Variants of NP2, NP2-4mg and NP2-6mg, Compared to Nicotine Lozenge 4mg (Loz-4mg) and Nicotine Gum 4mg (Gum-4mg)
Conditions: Tobacco Use Interventions: Other: NP2-4mg; Other: NP2-6 mg; Other: Loz-4mg; Other: Gum-4mg Sponsors: Philip Morris Products S.A. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

Study to Assess PK, PD, Nicotine Extraction, Palatability, Subjective Effects of Nicotine Pouches - Daily Nicotine Users
Conditions: Nicotine Use Disorder Interventions: Other: Test product 1 - Test product 2 - Comparator product Sponsors: Amplicon AB Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials

E-cigarette Harm Reduction Among PLWHA in South Africa
Conditions: Tobacco Smoking Interventions: Other: Nicotine Replacement Therapy (NRT); Other: E-Cigarette (EC); Behavioral: Counseling Sponsors: NYU Langone Health; JOHN E FOGARTY INTERNATIONAL CENTER FOR ADVANCED STUDY IN THE HEALTH SCIENCES (FIC) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 14, 2023 Category: Research Source Type: clinical trials