Central Vein Sign as an Imaging Biomarker of Multiple Sclerosis
(MedPage Today) -- MedPage Today brought together three expert leaders for a virtual roundtable discussion on the joint meeting of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the American Committee for... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 3, 2023 Category: Neurology Source Type: news

Eculizumab Substantially Reduces Myasthenia Gravis Events
(MedPage Today) -- PHOENIX – Generalized myasthenia gravis patients had dramatically lower incidence of flares and crises after starting on the complement component 5 inhibitor eculizumab (Soliris), data from a real-world registry showed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 2, 2023 Category: Neurology Source Type: news

Pulsed Field Ablation May Bridge Gender Gap in AF Ablation
(MedPage Today) -- The clinical benefits and safety of pulsed field ablation (PFA) for atrial fibrillation (Afib) appeared to span both sexes in real-world practice, according to a postapproval registry from Europe. Among people who underwent... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 1, 2023 Category: Neurology Source Type: news

Year in Review: Huntington's Disease
(MedPage Today) -- A new drug was approved for Huntington's chorea in 2023, and novel insights about Huntington's disease emerged in new research. Valbenazine for Huntington's Chorea In August, the FDA expanded the label for valbenazine (Ingrezza... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 1, 2023 Category: Neurology Source Type: news

Probe of Alzheimer's Researcher Halted; Dementia and Triglycerides; Migraine Genes
(MedPage Today) -- City University of New York temporarily halted its probe into the alleged scientific misconduct of faculty member and Alzheimer's researcher Hoau-Yan Wang, PhD, citing concerns about the integrity of the investigation. (New York... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 1, 2023 Category: Neurology Source Type: news

Dementia Risk Rises When Deep Sleep Falls
(MedPage Today) -- Less slow-wave sleep over time raised the risk of incident dementia, prospective data showed. Each percentage decrease in slow-wave sleep per year in people 60 and older was tied to a 27% increase in dementia risk (HR 1.27... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 31, 2023 Category: Neurology Source Type: news

Subcutaneous Alzheimer's Drug May Be on the Horizon
(MedPage Today) -- A subcutaneous version of the newly approved Alzheimer's drug lecanemab (Leqembi) may be on the horizon. Weekly subcutaneous lecanemab 100 mg/mL injection appeared to be as effective at amyloid plaque removal as biweekly IV... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 27, 2023 Category: Neurology Source Type: news

Emerging Biomarkers of Multiple Sclerosis in Blood and CSF
(MedPage Today) -- MedPage Today brought together three expert leaders for a virtual roundtable discussion on the joint meeting of the European Committee for Treatment and Research in Multiple Sclerosis (ECTRIMS) and the American Committee for... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 27, 2023 Category: Neurology Source Type: news

Alzheimer's Pathology and COVID; Human Brain Cell Maps Unveiled; TCE Ban Proposed
(MedPage Today) -- Researchers teased apart possible relationships between COVID-19 and Alzheimer's disease pathology. (Journal of Neurochemistry) COVID infection was tied to an increased risk of a diagnosis of Guillain-Barré syndrome within... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 24, 2023 Category: Neurology Source Type: news

Widespread Selenium Deficiency Seen in Huntington's Disease Brains
(MedPage Today) -- Huntington's disease brains had widespread differences in metal levels compared with controls, post-mortem data showed. Decreases in selenium levels were seen in 11 of 11 investigated brain regions in Huntington's disease, reported... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 24, 2023 Category: Neurology Source Type: news

S1P Receptor Modulator May Boost Cognitive Processing Speed in Early MS
(MedPage Today) -- Treatment with ozanimod (Zeposia) led to clinically meaningful improvement in cognitive processing speed among people with early relapsing multiple sclerosis (RMS), an ad hoc interim analysis of the phase IIIb ENLIGHTEN trial... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 19, 2023 Category: Neurology Source Type: news

BTK Inhibitor Reduces Brain Lesions in Relapsing MS
(MedPage Today) -- MILAN -- Investigational fenebrutinib reduced brain lesions in relapsing multiple sclerosis (MS) patients and showed evidence of central nervous system (CNS) penetration, data from the phase II FENopta study showed. Compared... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 19, 2023 Category: Neurology Source Type: news

Neurofilament Light Predicts MS Worsening in Silent Progression
(MedPage Today) -- Neuroaxonal pathology occurred in advance of -- not coincident with -- clinical worsening in multiple sclerosis (MS), particularly in patients with "silent progression" or progression independent of relapse activity (PIRA... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 17, 2023 Category: Neurology Source Type: news

Path to Multiple Sclerosis Cure on the Horizon
(MedPage Today) -- MILAN -- A path to a cure for multiple sclerosis (MS) may be on the horizon, a top MS researcher suggested. The field faces a great opportunity to advance from suppressing the disease to curing it, said Stephen Hauser, MD... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 16, 2023 Category: Neurology Source Type: news

Subcutaneous Ocrelizumab Not Inferior to IV Infusion
(MedPage Today) -- MILAN -- An investigational 10-minute subcutaneous injection of ocrelizumab (Ocrevus) was non-inferior to the established IV infusion formulation of the drug in multiple sclerosis (MS), the phase III OCARINA II trial showed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 14, 2023 Category: Neurology Source Type: news