Spinal Delivery of Gene Therapy Promising for Neurodegenerative Disease
(MedPage Today) -- Gene therapy delivered for the first time via lumbar puncture showed promise of benefit in slowing progression of giant axonal neuropathy (GAN) in a phase I clinical trial.
The slope of change in motor function went from -7... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 21, 2024 Category: Neurology Source Type: news
Be Wary of Flawed Diagnosis Criteria for ME/CFS
(MedPage Today) -- A recent CDC-funded paper in the Journal of Clinical Medicine suggests that the agency's Fukuda empirical criteria for diagnosing Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) identified the highest proportion of... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 20, 2024 Category: Neurology Source Type: news
New Data Fuel Debate on Autism and Prenatal Topiramate Exposure
(MedPage Today) -- The incidence of autism spectrum disorder was higher among children exposed to topiramate in the second half of pregnancy than in the general population, but not relative to other children born to women with epilepsy, a study... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 20, 2024 Category: Neurology Source Type: news
Major Congenital Malformation Risk Lower With Several Epilepsy Drugs
(MedPage Today) -- Levetiracetam, oxcarbazepine, and lamotrigine had the lowest prevalence of major congenital malformations (MCMs) compared with other monotherapy anti-seizure medications (ASMs) for pregnant women with epilepsy, a prospective... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 20, 2024 Category: Neurology Source Type: news
Epstein-Barr and MS; When Lewy Pathology Starts; Alzheimer's Blood Test Assessed
(MedPage Today) -- Antibody response to anti-Epstein-Barr virus nuclear antigen 1 (EBNA-1) may be a risk factor for multiple sclerosis (MS), a small study suggested. (JAMA Neurology)
ND0612, a subcutaneous levodopa-carbidopa infusion for Parkinson... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 19, 2024 Category: Neurology Source Type: news
Space Flights Provoke Tension Headaches, Migraine
(MedPage Today) -- Space flight appeared to provoke headaches in healthy astronauts, a prospective study showed.
Of 24 astronauts who participated in long-haul space flights -- ones that lasted at least 10 days -- 91.7% experienced one or... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 13, 2024 Category: Neurology Source Type: news
Viagra and Alzheimer's; Migraine Consensus Statement; FDA Updates Drug Guidance
(MedPage Today) -- More data supported links between the erectile dysfunction drug sildenafil (Viagra) and reduced Alzheimer's risk. (Journal of Alzheimer's Disease)
The American Headache Society issued a consensus position statement saying drugs... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 12, 2024 Category: Neurology Source Type: news
Breastfeeding While Taking MS Monoclonal Antibody Drugs Appears Safe
(MedPage Today) -- Exposure to multiple sclerosis (MS) monoclonal antibody treatment during breastfeeding appeared to have no negative effect on the early development or health of infants, registry data in Germany showed.
Over the first 3 years... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 11, 2024 Category: Neurology Source Type: news
Deaths Due to Alcohol Use; Steps for the Sedentary
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 9, 2024 Category: Neurology Source Type: news
Biden Defends Reproductive Rights, Touts Drug-Pricing Law in State of the Union
(MedPage Today) -- President Biden hammered home his commitment to reproductive healthcare and touted his administration's health-related accomplishments -- from lowering drug costs to expanding access to affordable healthcare -- during his... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 8, 2024 Category: Neurology Source Type: news
BTK Inhibitor Fails to Eliminate Paramagnetic Rim Lesions in MS
(MedPage Today) -- WEST PALM BEACH, Fla. -- Tolebrutinib, an investigational brain-penetrant Bruton's tyrosine kinase (BTK) inhibitor, failed to eliminate paramagnetic rim lesions (PRLs) in people with multiple sclerosis (MS), a small phase IIa... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 7, 2024 Category: Neurology Source Type: news
Dementia More Common in People With Essential Tremor
(MedPage Today) -- Dementia was more common in people with essential tremor than in the general population, a prospective cohort study found.
Over 5 years, the cumulative prevalence of dementia was 18.5% and the average annual conversion rate... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 6, 2024 Category: Neurology Source Type: news
CVD Risks Tied to Teeny-Tiny Plastics Lodged in Atherosclerotic Plaque
(MedPage Today) -- It was common for tiny plastic particles from the environment to infiltrate people's vascular lesions, foreshadowing future cardiovascular disease in patients who underwent carotid endarterectomy, an observational study showed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 6, 2024 Category: Neurology Source Type: news
Evobrutinib Fails to Beat Teriflunomide in Relapsing MS
(MedPage Today) -- WEST PALM BEACH, Fla. -- The investigational oral Bruton's tyrosine kinase (BTK) inhibitor evobrutinib failed to distinguish itself from teriflunomide (Aubagio) in two phase III trials of relapsing multiple sclerosis (MS) patients... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 6, 2024 Category: Neurology Source Type: news
Investigational Agent Shows Benefit in Myasthenia Gravis
(MedPage Today) -- The investigational monoclonal antibody batoclimab led to significant improvement in activities of daily living in people with generalized myasthenia gravis (gMG), a multicenter phase III trial found.
The rate of sustained improvement... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - March 6, 2024 Category: Neurology Source Type: news
