Antihypertensives and Dementia; Peripheral Neuropathy Marker; Who Can Get Lecanemab?
(MedPage Today) -- New use of antihypertensive medications that stimulated rather than inhibited type 2 and 4 angiotensin II receptors was linked with lower dementia risk. (JAMA Network Open) Full data about an implanted endovascular brain-computer... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 10, 2023 Category: Neurology Source Type: news

Gabapentin and Opioids; Alzheimer's Drug Decision Nears; Neurology Education in 2035
(MedPage Today) -- Gabapentin will not cure the opioid crisis, JAMA Internal Medicine editors argued in response to recent research about overlapping gabapentin and opioid prescriptions. The Institute for Clinical and Economic Review (ICER), a... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 3, 2023 Category: Neurology Source Type: news

Paralysis Tied to Virus in Kids Goes Off-Script, Baffling CDC
In this report... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 2, 2023 Category: Neurology Source Type: news

Congressional Probe of Alzheimer's Drug Approval Finds Fault With FDA Actions
(MedPage Today) -- The FDA broke with its own protocols in reviewing and subsequently approving Alzheimer's drug aducanumab (Aduhelm), by inappropriately collaborating with drugmaker Biogen on briefing documents, holding unreported meetings, and... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 30, 2022 Category: Neurology Source Type: news

Novel Blood Test Detects Alzheimer's Neurodegeneration
(MedPage Today) -- A novel blood test to assess brain-derived tau detected Alzheimer's-related neurodegeneration and differentiated Alzheimer's from other neurodegenerative diseases. The test outperformed total tau and, unlike neurofilament light... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 30, 2022 Category: Neurology Source Type: news

Anti-CD20 Agent Gains Approval for Multiple Sclerosis
(MedPage Today) -- Ublituximab (Briumvi), a monoclonal antibody targeting CD20, was approved for relapsing forms of multiple sclerosis (MS), including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - December 29, 2022 Category: Neurology Source Type: news

Alzheimer's Agent Fails; Antiseizure Drug Use Rises; Stress and Post-COVID Outcomes
(MedPage Today) -- Phase III studies of investigational gantenerumab did not meet their primary endpoints of slowing clinical decline in early Alzheimer's disease, the Roche Group said. Beta-amyloid removal also was lower than expected with the... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 15, 2022 Category: Neurology Source Type: news

One in Five May Recall Near-Death Experience After CPR
(MedPage Today) -- Researchers are making new strides when it comes to understanding death, according to a new study. One in five people who survive cardiac arrest after cardiopulmonary resuscitation (CPR) may recall lucid experiences of death... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 11, 2022 Category: Neurology Source Type: news

Alzheimer's Risk and COVID; Obesity in New MS Patients; Repurposing Telmisartan?
(MedPage Today) -- A Mendelian randomization study found a potential association between genetically predicted COVID-19 and a higher risk of Alzheimer's disease. (Annals of Clinical and Translational Neurology) Neurologic involvement was seen... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 8, 2022 Category: Neurology Source Type: news

Early Signs of Parkinson's May Be Seen Years Before Diagnosis
(MedPage Today) -- Early signs of Parkinson's disease may emerge 6 years before diagnosis, an analysis of health insurance data showed. Sensory skin changes, diabetes, and inflammatory conditions were more prevalent in people subsequently diagnosed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 7, 2022 Category: Neurology Source Type: news

Higher Relapse Rate With Rituximab vs Ocrelizumab in MS Registry Data
(MedPage Today) -- Rituximab (Rituxan) did not show noninferiority compared with ocrelizumab (Ocrevus) in relapsing-remitting multiple sclerosis (MS), according to registry data. The annualized relapse rate (ARR) was higher in MS patients treated... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 2, 2022 Category: Neurology Source Type: news

Alzheimer's Trial Death; Dementia and Antihypertensives; Simvastatin in Parkinson's?
(MedPage Today) -- A trial investigator for the anti-amyloid drug lecanemab -- which showed cognitive benefit in a phase III trial of early Alzheimer's -- flagged the death of a trial participant following bleeding in the brain and said it... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - November 1, 2022 Category: Neurology Source Type: news

Can First MS Symptoms Be Delayed?
(MedPage Today) -- Dimethyl fumarate (Tecfidera) reduced the risk of the first symptom manifestation of multiple sclerosis (MS) in people with radiologically isolated syndrome (RIS), data from the ARISE trial showed. The risk of a first clinical... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 31, 2022 Category: Neurology Source Type: news

Genetic Testing in Epilepsy Helps Inform Patient Management
(MedPage Today) -- A genetic diagnosis of epilepsy frequently led to changes in clinical management and improved outcomes in patients of all ages, a retrospective cross-sectional study showed. Changes in clinical management followed a genetic... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 31, 2022 Category: Neurology Source Type: news

New Evidence Sheds Light on Stem Cell Transplantation for Progressive MS
(MedPage Today) -- Autologous hematopoietic stem cell transplantation (AHSCT) was not superior in preventing relapses or reducing disability progression than natalizumab (Tysabri) in progressive multiple sclerosis (MS), new research suggested... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - October 31, 2022 Category: Neurology Source Type: news