Potentially Protective Agent Shows Benefit in Niemann-Pick Type C
(MedPage Today) -- Patients with Niemann-Pick disease type C who received N-acetyl-L-leucine (NALL), an agent that potentially ameliorates lysosomal and metabolic dysfunction, showed reduced neurologic signs and symptoms after 3 months, a phase... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 31, 2024 Category: Neurology Source Type: news

GLP-1 Drugs Tame Brain Inflammation; Novel Painkiller Succeeds; Headache as Metaphor
(MedPage Today) -- Glucagon-like peptide 1 (GLP-1) receptor agonists that reduce obesity also dial down brain inflammation, leading researchers to investigate how these agents might help treat Alzheimer's or Parkinson's disease. (Nature) IV ketamine... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 31, 2024 Category: Neurology Source Type: news

Merrick Garland's Surgery; Neuralink's Human Brain Chip; Novel Drug Cuts Pain
(MedPage Today) -- Note that some links may require registration or subscription. U.S. Attorney General Merrick Garland is set to undergo back surgery this weekend. (Politico) King Charles III was released from the hospital following a prostate... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 30, 2024 Category: Neurology Source Type: news

Shunted Infantile Hydrocephalus Linked to Early Puberty in Girls
(MedPage Today) -- Girls who received a ventriculoperitoneal shunt for infantile hydrocephalus had an increased risk of early puberty, particularly those with myelomeningocele and repeated shunt revisions, a population-based cohort study showed... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 29, 2024 Category: Neurology Source Type: news

Researchers Propose New Parkinson's Definition Based on Biomarkers
(MedPage Today) -- Lewy body diseases -- Parkinson's disease and dementia with Lewy bodies -- should be defined as neuronal alpha-synuclein disease, not as clinical syndromes, a new position paper proposed. "Parkinson's disease and dementia... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 26, 2024 Category: Neurology Source Type: news

Sleep, Energy Levels Linked With Next-Day Headaches
(MedPage Today) -- Sleep quality and energy levels were linked to headache onset on the following day, a prospective observational study found. Lower average sleep quality (P<0.001) and poorer-than-average sleep quality on the previous night... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 25, 2024 Category: Neurology Source Type: news

Can Targeting Normoxemia Benefit Critically Ill Trauma Patients?
(MedPage Today) -- PHOENIX -- Targeting normoxemia in critically ill trauma patients appeared to increase supplemental oxygen-free days in a cluster randomized stepped-wedge trial that missed on statistical significance. Through 28 days, patients... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 24, 2024 Category: Neurology Source Type: news

Benzodiazepines Tied to Worse Outcomes in Progressive Supranuclear Palsy
(MedPage Today) -- People with progressive supranuclear palsy (PSP) who were prescribed benzodiazepine derivatives had a faster decline in PSP Rating Scale (PSPRS) scores than those who didn't have benzodiazepines, a post hoc analysis showed.... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 24, 2024 Category: Neurology Source Type: news

Unusual Visual Symptoms and Alzheimer's; Infections and Dementia; Head Trauma and MS
(MedPage Today) -- Posterior cortical atrophy -- a rare syndrome characterized by progressive visual impairment including constructional dyspraxia, space perception deficit, or simultagnosia -- presented as a young-onset dementia syndrome and... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 23, 2024 Category: Neurology Source Type: news

Gabapentinoid Use Continues to Climb
(MedPage Today) -- Gabapentinoid users increased from 4.0% in 2015 to 4.7% in 2021, Medical Expenditure Panel Survey (MEPS) data showed. Moreover, gabapentinoids -- which includes gabapentin and pregabalin -- continued to be used for chronic... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 22, 2024 Category: Neurology Source Type: news

Alzheimer's Blood Test Shows High Diagnostic Accuracy
(MedPage Today) -- A commercially available plasma assay that measured phosphorylated tau at threonine 217 (p-tau217) accurately identified biological Alzheimer's disease, data from three cohorts showed. Across all cohorts, the p-tau217 assay... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 22, 2024 Category: Neurology Source Type: news

Telehealth, Default Orders Show Promise in Palliative Care
(MedPage Today) -- A palliative telecare intervention improved quality of life for patients with chronic obstructive pulmonary disease (COPD), heart failure (HF), and interstitial lung disease (ILD), the ADAPT randomized clinical trial found.... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 17, 2024 Category: Neurology Source Type: news

Transparent Brain Implant; Neurology Pay Models; What Predicts Cognitive Reversion
(MedPage Today) -- A transparent polymer implant with a dense array of graphene electrodes on the brain's surface provided information about deep neural activity in transgenic mice. (Nature Nanotechnology) Audio-visual recordings of seven toddlers... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 16, 2024 Category: Neurology Source Type: news

Pain, Impairment Linger Months After ECMO for Most
(MedPage Today) -- Many extracorporeal membrane oxygenation (ECMO) patients experienced long-term neuropsychiatric symptoms, cognitive impairment, or functional impairment, a meta-analysis found. Fully 41% of ECMO patients had neuropsychiatric... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 11, 2024 Category: Neurology Source Type: news

MS Risk Linked to Ancient Migrations
(MedPage Today) -- Genetic risk for multiple sclerosis (MS) was brought into Europe by sheep and cattle herders migrating from the east approximately 5,000 years ago, DNA profiles from archaeological bones and teeth suggested. Migration among... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 10, 2024 Category: Neurology Source Type: news