Do Epilepsy Drugs During Pregnancy Influence Kids' Epilepsy Risk?
(MedPage Today) -- Children of mothers with epilepsy who used valproate or other antiseizure medications (ASMs) during pregnancy were more likely to develop epilepsy as well, a cohort study of more than 38,000 kids suggested, although causality... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 26, 2024 Category: Neurology Source Type: news

CAR-T for Autoimmune Disease; Methods of Illegal Opioid Overdose
(MedPage Today) -- TTHealthWatch is a weekly podcast from Texas Tech. In it, Elizabeth Tracey, director of electronic media for Johns Hopkins Medicine in Baltimore, and Rick Lange, MD, president of the Texas Tech University Health Sciences Center... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 24, 2024 Category: Neurology Source Type: news

Motor Function in Spinal Muscular Atrophy May Improve With Adjunctive Apitegromab
(MedPage Today) -- Some patients with later-onset spinal muscular atrophy (SMA) type 2 and type 3 had improved motor function when the investigational monoclonal antibody apitegromab was added to their treatment, the phase II TOPAZ trial found... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 23, 2024 Category: Neurology Source Type: news

Alzheimer's Biomarkers Show Specific Changes 20 Years Before Diagnosis
(MedPage Today) -- Biomarkers evolved in a temporal sequence over 20 years in people who developed Alzheimer's disease, a nested case-control study in China showed. Over a median follow-up of 19.9 years, cerebrospinal fluid (CSF) and imaging biomarkers... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 21, 2024 Category: Neurology Source Type: news

Herpes-Dementia Link; How COVID Affects the Brain; FDA to Decide on Duchenne Drug
(MedPage Today) -- A prospective study in Sweden reported a link between herpes simplex virus and dementia. (Journal of Alzheimer's Disease) Researchers differentiated people with Parkinson's disease from healthy controls with 68% accuracy using... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 20, 2024 Category: Neurology Source Type: news

Highly Effective Therapies Early in Pediatric MS Linked to Reduced Relapse Risk
(MedPage Today) -- Compared with moderately effective therapies, initial use of highly effective therapies for pediatric-onset multiple sclerosis (MS) was associated with a reduced risk of relapse, a retrospective cohort study suggested. Among... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 17, 2024 Category: Neurology Source Type: news

Umbilical Cord Milking in Non-Vigorous Infants Didn't Impact Neurodevelopment
(MedPage Today) -- NATIONAL HARBOR, Md. -- Compared to early cord clamping (ECC), umbilical cord milking (UCM) in non-vigorous infants had short-term benefits without any long-term adverse impacts on neurodevelopment, according to the cluster... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 15, 2024 Category: Neurology Source Type: news

Novel Anti-CD40L Antibody Slows New Brain Lesions in Relapsing MS
(MedPage Today) -- Frexalimab, an investigational second-generation CD40 ligand (CD40L) inhibitor, led to fewer new gadolinium-enhancing T1-weighted lesions in relapsing multiple sclerosis (MS), a phase II trial showed. At week 12, the adjusted... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 14, 2024 Category: Neurology Source Type: news

One in 10 People With COVID During Pregnancy Will Develop Long COVID
(MedPage Today) -- NATIONAL HARBOR, Md. -- One in 10 people who were pregnant at their index COVID-19 infection developed long COVID, according to an analysis of a pregnancy cohort in the NIH's RECOVER Initiative. In the final cohort of 1,502... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 13, 2024 Category: Neurology Source Type: news

When Does Brain Death Occur? Parkinson's-Paraquat Links; AI Boosts ARIA Detection
(MedPage Today) -- Controversy continues over when physicians should declare brain death, NPR reported. The EPA released a new draft report affirming the safety of paraquat, saying the evidence tying Parkinson's disease in humans to paraquat exposure... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 13, 2024 Category: Neurology Source Type: news

Dementia Predicted 10 Years Before Diagnosis
(MedPage Today) -- Blood protein profiles predicted future dementia in healthy adults, a large longitudinal study showed. Blood samples from over 50,000 people in the U.K. Biobank showed that four proteins -- glial fibrillary acidic protein... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 13, 2024 Category: Neurology Source Type: news

No Change in Huntington's Motor Symptoms With Investigational Drug
(MedPage Today) -- Investigational laquinimod did not change motor symptoms of Huntington's disease after 1 year but did significantly reduce caudate volume loss compared with placebo, the phase II LEGATO-HD trial found. At week 52, mean change... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 8, 2024 Category: Neurology Source Type: news

Corticosteroid Still Doesn't Help After Stroke in the Thrombectomy Era
(MedPage Today) -- PHOENIX -- A short course of low-dose methylprednisolone added to endovascular thrombectomy after acute ischemic stroke did not improve outcomes overall, though there was a lower rate of mortality, the randomized MARVEL trial... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 8, 2024 Category: Neurology Source Type: news

Greco-Roman Dementia; Prion Disease Vigilance; ChatGPT and Alzheimer's
(MedPage Today) -- Cognitive decline was rarely mentioned by ancient Greek and Roman authors, leading researchers to question whether dementia is a modern disease. (Journal of Alzheimer's Disease) Immune response may be responsible for neurologic... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - February 6, 2024 Category: Neurology Source Type: news

Controversial Alzheimer's Drug Abandoned
(MedPage Today) -- Biogen will discontinue its controversial Alzheimer's disease drug aducanumab (Aduhelm), the company announced Wednesday. The drugmaker will stop developing and selling aducanumab, an anti-amyloid monoclonal antibody that received... (Source: MedPage Today Neurology)
Source: MedPage Today Neurology - January 31, 2024 Category: Neurology Source Type: news