What Causes Proteinuria?
Discussion
Proteinuria occurs relatively often in pediatric practice with 5-15% of school children having transient proteinuria, the most common cause. However, proteinuria can be a sign of kidney disease. Therefore, it is important to evaluate the proteinuria in light of the clinical situation. A good history and physical examination along with a full urinalysis and/or BUN and creatinine, or urine protein/creatinine ratio may be all that is necessary. Another patient with edema, hypertension or hematuria needs a fuller evaluation and treatment. Proteinuria is usually categorized into three groups to assist with evaluation...
Source: PediatricEducation.org - August 18, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Saved by her grandma, the six-year-old girl who needed kidney after more than 30 operations
Ella Chadwick, from Manchester, was born with the rare condition congenital nephrotic syndrome, which caused both her kidneys to fail when she was 19 months old. (Source: the Mail online | Health)
Source: the Mail online | Health - May 27, 2014 Category: Consumer Health News Source Type: news
Questcor reports positive clinical trial results of Acthar in nephrotic syndrome patients
US-based biopharmaceutical firm Questcor Pharmaceuticals has reported results from an investigator-initiated clinical trial evaluating the dosing and effectiveness of HP Acthar Gel (repository corticotropin) in 20 patients with nephrotic syndrome due… (Source: Drug Development Technology)
Source: Drug Development Technology - April 22, 2014 Category: Pharmaceuticals Source Type: news
Children with glomerular kidney disease more likely to have hypertension as adults
Men who as children had glomerular disease, a disorder of the portion of the kidney that filters blood and one that usually resolves with time, were more likely than men without childhood glomerular disease to have high blood pressure as an adult, according to a study in the March 19 issue of JAMA.Glomerular disease was defined for this study as glomerulonephritis or nephrotic syndrome (both are kidney disorders). Most children who develop glomerular disease have a favorable prognosis with complete resolution of all signs and symptoms. (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - March 20, 2014 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
Martin Barratt obituary
Paediatric nephrologist whose research led to the improved treatment of common childhood kidney diseasesMartin Barratt, who has died aged 77 from a progressive form of muscular dystrophy, was professor of paediatric nephrology at the Institute of Child Health, London, and consultant nephrologist at Great Ormond Street Hospital for Children. He was one of the first to establish a specialist service for children with kidney diseases in Britain, developing a model of interdisciplinary care that was later adopted by many other centres throughout the world. His research led to improved understanding and treatment of many common...
Source: Guardian Unlimited Science - February 3, 2014 Category: Science Authors: Michael Levin Tags: theguardian.com Children Obituaries Medical research Hospitals NHS Science Source Type: news
Nephrotic syndrome following mercury vapor exposure
3 out of 5 stars
Mercury poisoning from home gold amalgam extraction. Saleem M et al. Med J Aust 2013;199:125-127.
No abstract available
This case report describes a 62-year-old man who presented with flu-like symptoms and increasing shortness of breath. History revealed that he had recently attempted to extract gold from mercury-containing amalgam by heating the amalgam in a pan. As a result, he had been exposed to mercury fumes for approximately 3 hours.
Workup revealed pneumonitis, as well as elevated blood and urine mercury levels. The patient was treated with chelation (DMSA) and steroids. One month later he ...
Source: The Poison Review - July 24, 2013 Category: Toxicology Authors: Leon Tags: Medical mercury toxicity mercury vapor nephrotic syndrome pneumonitis renal toxicity Source Type: news
RCT: Immunosuppression for progressive membranous nephropathy
Source: Lancet
Area: News
Membranous nephropathy is the most common cause of primary nephrotic syndrome in adults and leads to end-stage renal disease in more than 20% of patients. Although immunosuppressive therapy benefits some patients, trial evidence for the subset of patients with declining renal function is not available. The UK Renal Association Clinical Trials Committee's glomerulonephritis subgroup aimed to assess whether immunosuppression preserves renal function in patients with idiopathic membranous nephropathy with declining renal function.
This trial was conducted in 37 renal units across the UK a...
Source: NeLM - News - January 10, 2013 Category: Drugs & Pharmacology Source Type: news
Extending Steroid Treatment Does Not Benefit Children With Hard-To-Treat Kidney Disease
Extending steroid treatment for the most common form of kidney disease in children provides no benefit for preventing relapses or side effects, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN). The findings challenge previous assumptions about optimal treatment strategies for this disease. Nephrotic syndrome is the most common kidney disease in childhood. Children with the disease are at risk of developing severe infections and other complications because their kidneys leak important proteins from the blood into the urine... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - January 2, 2013 Category: Consumer Health News Tags: Urology / Nephrology Source Type: news
