Sulfoxides in medicine
Curr Opin Chem Biol. 2023 Jun 10;76:102340. doi: 10.1016/j.cbpa.2023.102340. Online ahead of print.ABSTRACTIn the review, current status of sulfoxides on the pharmaceutical market is discussed. In the first part of the article, natural sulfoxides will be described with a special focus on sulforaphane and amanitin, a mushroom toxin which has been developed as payload in antibody drug conjugates in the possible cancer treatment. Controversies associated with the medical use of dimethylsulfoxide are briefly described in the next section. In the part devoted to PPIs, the benefits of using pure enantiomers (chiral switch) are d...
Source: Current Opinion in Chemical Biology - June 12, 2023 Category: Biochemistry Authors: El żbieta Wojaczyńska Jacek Wojaczy ński Source Type: research

Use of psychoactive substances as a treatment for psychosis
CONCLUSION: The results obtained open up the possibility of having a guideline for clinicians/health professionals on the use of cannabidiol, modafinil and ketamine as adjunctive treatment for patients with psychotic conditions.PMID:37231549 | DOI:10.33588/rn.7611.2023077 (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 26, 2023 Category: Neurology Authors: E Serrano-Jim énez M G de Lucas-Moreno Source Type: research

Use of psychoactive substances as a treatment for psychosis
CONCLUSION: The results obtained open up the possibility of having a guideline for clinicians/health professionals on the use of cannabidiol, modafinil and ketamine as adjunctive treatment for patients with psychotic conditions.PMID:37231549 | DOI:10.33588/rn.7611.2023077 (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 26, 2023 Category: Neurology Authors: E Serrano-Jim énez M G de Lucas-Moreno Source Type: research

Use of psychoactive substances as a treatment for psychosis
CONCLUSION: The results obtained open up the possibility of having a guideline for clinicians/health professionals on the use of cannabidiol, modafinil and ketamine as adjunctive treatment for patients with psychotic conditions.PMID:37231549 | DOI:10.33588/rn.7611.2023077 (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 26, 2023 Category: Neurology Authors: E Serrano-Jim énez M G de Lucas-Moreno Source Type: research

Use of psychoactive substances as a treatment for psychosis
CONCLUSION: The results obtained open up the possibility of having a guideline for clinicians/health professionals on the use of cannabidiol, modafinil and ketamine as adjunctive treatment for patients with psychotic conditions.PMID:37231549 | DOI:10.33588/rn.7611.2023077 (Source: Revista de Neurologia)
Source: Revista de Neurologia - May 26, 2023 Category: Neurology Authors: E Serrano-Jim énez M G de Lucas-Moreno Source Type: research