Monitoring in vitro antibacterial efficacy of 26 Indian spices against multidrug resistant urinary tract infecting bacteria
Conclusion The most effective and unique 16 spice plants recorded for the in vitro control of MDR uropathogens could further be pursued for the development of complementary and supplementary medicine against MDR bacteria. (Source: Integrative Medicine Research)
Source: Integrative Medicine Research - October 12, 2014 Category: Complementary Medicine Source Type: research

L-Carvone Induces p53, Caspase 3 Mediated Apoptosis and Inhibits the Migration of Breast Cancer Cell Lines.
Abstract A wide variety of natural compounds exists that possesses significant cytotoxic as well as chemopreventive activity through induction of apoptosis in cancer cells. The antiproliferative and apoptotic effect of L-carvone, an active component of spearmint (Mentha spicata) was studied on breast cancer (MCF 7 and MDA MB 231) and normal (MCF 10A) cell lines, and insight into its mechanism of action was attained. L-carvone inhibited proliferation of MCF 7 (IC50 1.2 mM) and MDA MB 231 cells (IC50 1.0 mM) and inhibited the migration of breast cancer cell lines. L-carvone induced apoptosis as observed by...
Source: Nutrition and Cancer - March 10, 2014 Category: Cancer & Oncology Authors: Patel PB, Thakkar VR Tags: Nutr Cancer Source Type: research

The Association between Chromaticity, Phenolics, Carotenoids, and In Vitro Antioxidant Activity of Frozen Fruit Pulp in Brazil: An Application of Chemometrics
Abstract A total of 19 Brazilian frozen pulps from the following fruits: açai (Euterpe oleracea), blackberry (Rubus sp.), cajá (Spondias mombin), cashew (Anacardium occidentale), cocoa (Theobroma cacao), coconut (Cocos nucifera), grape (Vitis sp.), graviola (Annona muricata), guava (Psidium guajava), papaya (Carica papaya), peach (Prunus persica), pineapple (Ananas comosus), pineapple and mint (A. comosus and Mentha spicata), red fruits (Rubus sp. and Fragaria sp.), seriguela (Spondias purpurea), strawberry (Fragaria sp.), tamarind (Tamarindus indica), umbu (Spondias tuberosa), and yellow passion fruit (Passiflora edulis...
Source: Journal of Food Science - February 18, 2014 Category: Food Science Authors: Acácio Antonio Ferreira Zielinski, Suelen Ávila, Vivian Ito, Alessandro Nogueira, Gilvan Wosiacki, Charles Windson Isidoro Haminiuk Tags: C: Food Chemistry Source Type: research

Antibacterial Effect of Mentha spicata Essential Oil on Listeria monocytogenes in Traditional Lighvan Cheese
AbstractListeria monocytogenes is a foodborne pathogen that is widespread in the environment. There are several reports on the isolation of L. monocytogenes from many types of cheeses. The aim of this study was to evaluate the antibacterial effect of Mentha spicata essential oil on L. monocytogenes in traditional Lighvan cheese. L. monocytogenes was added to the raw ewe's milk and M. spicata essential oil was subsequently mixed with the milk at concentrations of 0, 2 and 2.5%. After producing the cheese, sampling performed until 60 days. Results of this study showed that M. spicata essential oil at all concentrat...
Source: Journal of Food Safety - October 16, 2013 Category: Food Science Authors: Mir‐Hassan Moosavy, Saber Esmaeili, Ehsan Mostafavi Tags: Original Article Source Type: research

2,2-Diphenyl-1-picrylhydrazyl as a screening tool for recombinant monoterpene biosynthesis
Conclusions: The DPPH assay is useful for detecting biosynthesis of limonene. Although the assay cannot be used quantitatively, it proved successful in ranking limonene production conditions qualitatively and thus is suitable as a first-tier screen. The DPPH assay will likely be applicable in detecting biosynthesis of several other monoterpenes and for screening libraries of monoterpene-producing strains. (Source: Microbial Cell Factories)
Source: Microbial Cell Factories - August 23, 2013 Category: Microbiology Authors: James BehrendorffClaudia VickersPanagiotis ChrysanthopoulosLars Nielsen Source Type: research

Adverse effects of herbal medicines: an overview of systematic reviews.
Abstract This overview of systematic reviews (SRs) aims to evaluate critically the evidence regarding the adverse effects of herbal medicines (HMs). Five electronic databases were searched to identify all relevant SRs, with 50 SRs of 50 different HMs meeting our inclusion criteria. Most had only minor weaknesses in methods. Serious adverse effects were noted only for four HMs: Herbae pulvis standardisatus, Larrea tridentate, Piper methysticum and Cassia senna. The most severe adverse effects were liver or kidney damage, colon perforation, carcinoma, coma and death. Moderately severe adverse effects were no...
Source: Clinical Medicine - February 1, 2013 Category: Journals (General) Authors: Posadzki P, Watson LK, Ernst E Tags: Clin Med Source Type: research