Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Hematol Oncol Clin North Am. 2023 Aug 12:S0889-8588(23)00102-8. doi: 10.1016/j.hoc.2023.06.012. Online ahead of print.ABSTRACTWaldenström macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and nonspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progressio...
Source: The Medical Clinics of North America - August 13, 2023 Category: General Medicine Authors: Mark Bustoros Caitlin Gribbin Jorge J Castillo Richard Furman Source Type: research

Biomarkers of Progression and Risk Stratification in Asymptomatic Waldenstr öm Macroglobulinemia
Waldenstr öm macroglobulinemia is an indolent IgM-secreting B-cell lymphoplasmacytic lymphoma that is preceded by an asymptomatic stage. Clinical and molecular features have been used in risk models to predict progression rates in different asymptomatic subgroups. Risk models used both disease-specific and n onspecific biomarkers for asymptomatic patients. Recently, models that incorporate continuous variables rather than distinct cutoffs have emerged to more accurately predict the risk of progression. Integrating genetic alterations to the clinical models is a promising approach that could improve risk stratification and...
Source: Hematology/Oncology Clinics of North America - August 12, 2023 Category: Cancer & Oncology Authors: Mark Bustoros, Caitlin Gribbin, Jorge J. Castillo, Richard Furman Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research

Secondary amyloidosis with concomitant gastric GIST and gastric adenocarcinoma - A case report
Indian J Pathol Microbiol. 2023 Jul-Sep;66(3):594-596. doi: 10.4103/ijpm.ijpm_461_21.ABSTRACTSecondary amyloidosis is a well-established entity and has been described in association with chronic inflammatory conditions such as rheumatoid arthritis, ankylosing spondylitis, bronchiectasis, tuberculosis, etc., It has also been reported in association with neoplasms such as Hodgkin's lymphoma, Waldenstrom's macroglobulinemia, renal cell carcinoma, lung carcinoma, etc. However, only a few case reports documenting the association of amyloidosis with gastrointestinal tumor (GIST) and gastric adenocarcinoma are available in the li...
Source: Indian Journal of Pathology and Microbiology - August 2, 2023 Category: Pathology Authors: Ankita Soni Nishant Batta Shefali Mehmi Vikram Narang Bhavna Garg Harpreet Kaur Source Type: research