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Critical assessment of the endocrine potential of Linalool and Linalyl acetate: proactive testing strategy assessing estrogenic and androgenic activity of Lavender oil main components
This study aims to follow-up on these critical findings reported by testing Lin and LinAc in several studies in line with current guidance and regulatory framework. No relevant anti-/ER and AR-mediated activity was observed in recombinant yeast cell-based screening tests and guideline reporter gene in vitro assays in mammalian cells. Findings in the screening test suggested an anti-androgenic activity, which could not be confirmed in the respective mammalian cell guideline assay. Mechanistic guideline in vivo studies (Uterotrophic and Hershberger assays) with Lin did not show significant dose related changes in estrogen or...
Source: Archives of Toxicology - October 31, 2023 Category: Toxicology Authors: Lars Hareng Susanne N Kolle Caroline Gomes Steffen Schneider Markus Wahl Source Type: research

& amp;lt;i & amp;gt;In vitro & amp;lt;/i & amp;gt; Characterization of the Essential Oil Extracted from & amp;lt;i & amp;gt;Lavandula dentata & amp;lt;/i & amp;gt; and its Application in the Field of Biotherapy
Conclusion:&lt;/b&gt; &lt;i&gt;Lavandula dentata&lt;/i&gt; EO processes great antimicrobial, analgesic, anti- diabetic and anticoagulant properties. Further investigations into its mechanisms of action and safety profile are warranted to fully exploit its therapeutic potential.PMID:37902044 | DOI:10.3923/pjbs.2023.300.310 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - October 30, 2023 Category: Biomedical Science Authors: Mounira Kara Ali Wahiba Kara Ali Asma Ait Kaki Berrabah Hadil Rechachi Aicha Noreddine Kacem Chaouche Source Type: research

Launching Lavender Response Teams Across a Health Care System
This article describes how this organization accomplished this and may serve as a resource for other health care systems interested in establishing their own version of Code Lavender. (Source: Nurse Leader)
Source: Nurse Leader - October 28, 2023 Category: Nursing Authors: Kathleen Ann DeMarco, Marci Resnicoff Source Type: research

Molecules, Vol. 28, Pages 7259: In Vitro Antifungal Activity of Selected Essential Oils against Drug-Resistant Clinical Aspergillus spp. Strains
Conclusions: These results demonstrate the antimicrobial potential of some EOs and support the research of new alternatives or complementary therapies based on EOs. (Source: Molecules)
Source: Molecules - October 25, 2023 Category: Chemistry Authors: Valeria Allizond Lorenza Cavallo Janira Roana Narcisa Mandras Anna Maria Cuffini Vivian Tullio Giuliana Banche Tags: Article Source Type: research

Molecules, Vol. 28, Pages 7142: Development of Essential Oil-Loaded Polymeric Nanocapsules as Skin Delivery Systems: Biophysical Parameters and Dermatokinetics Ex Vivo Evaluation
In conclusion, NC-EOs can be used as an alternative antioxidant for skin care. (Source: Molecules)
Source: Molecules - October 18, 2023 Category: Chemistry Authors: Perla Giovanna Silva-Flores Sergio Arturo Galindo-Rodr íguez Luis Alejandro P érez-López Roc ío Álvarez-Román Tags: Article Source Type: research

Olfactory training in normosmic individuals: a randomised controlled trial
CONCLUSIONS: OT had a limited effect on olfactory function in individuals with normosmia. Further, the superiority of a more extended OT is not supported by this study, and shorter training sessions seem to improve compliance with OT.PMID:37847818 | DOI:10.4193/Rhin23.229 (Source: Rhinology)
Source: Rhinology - October 17, 2023 Category: ENT & OMF Authors: I T Heian W M Thorstensen T A Myklebust T Hummel S Nordg ård M Bratt A S Helvik A S Helvik Source Type: research