Sleep Disorder Kleine-Levin Syndrome (KLS) Joins the List of Polygenic Brain Disorders Associated with Obstetric Complications
Cell Mol Neurobiol. 2023 Aug 9. doi: 10.1007/s10571-023-01391-z. Online ahead of print.ABSTRACTKleine-Levin Syndrome is a rare neurological disorder with onset typically during adolescence that is characterized by recurrent episodes of hypersomnia, behavioral changes, and cognitive abnormalities, in the absence of structural changes in neuroimaging. As for many functional brain disorders, the exact disease mechanism in Kleine-Levin Syndrome is presently unknown, preventing the development of specific treatment approaches or protective measures. Here we review the pathophysiology and genetics of this functional brain disord...
Source: Cellular and Molecular Neurobiology - August 8, 2023 Category: Cytology Authors: Michael Hamper Rainald Schmidt-Kastner Source Type: research
Sleep Disorder Kleine-Levin Syndrome (KLS) Joins the List of Polygenic Brain Disorders Associated with Obstetric Complications
Cell Mol Neurobiol. 2023 Aug 9. doi: 10.1007/s10571-023-01391-z. Online ahead of print.ABSTRACTKleine-Levin Syndrome is a rare neurological disorder with onset typically during adolescence that is characterized by recurrent episodes of hypersomnia, behavioral changes, and cognitive abnormalities, in the absence of structural changes in neuroimaging. As for many functional brain disorders, the exact disease mechanism in Kleine-Levin Syndrome is presently unknown, preventing the development of specific treatment approaches or protective measures. Here we review the pathophysiology and genetics of this functional brain disord...
Source: Cellular and Molecular Neurobiology - August 8, 2023 Category: Cytology Authors: Michael Hamper Rainald Schmidt-Kastner Source Type: research
