An eye for detail: Eye movements and attention at the foveal scale
Vision Res. 2023 Jun 26;211:108277. doi: 10.1016/j.visres.2023.108277. Online ahead of print.ABSTRACTHuman vision relies on a tiny region of the retina, the 1-deg foveola, to achieve high spatial resolution. Foveal vision is of paramount importance in daily activities, yet its study is challenging, as eye movements incessantly displace stimuli across this region. Here I will review work that, building on recent advances in eye-tracking and gaze-contingent display, examines how attention and eye movements operate at the foveal level. This research highlights how exploration of fine spatial detail unfolds following visuomoto...
Source: Vision Research - June 28, 2023 Category: Opthalmology Authors: Martina Poletti Source Type: research

Looking away to see: The acquisition of a search habit away from the saccade direction
Vision Res. 2023 Jun 23;211:108276. doi: 10.1016/j.visres.2023.108276. Online ahead of print.ABSTRACTGrowing evidence has shown that attention can be habit-like, unconsciously and persistently directed toward locations that have frequently contained search targets in the past. The attentional preference typically arises when the eye gaze aligns with the attended location. Here we tested whether this spatial alignment is necessary for the acquisition of a search habit. To divert eye movements away from an attended location, we used gaze-contingent eye tracking, restricting the visible portion of the screen to an area opposi...
Source: Vision Research - June 25, 2023 Category: Opthalmology Authors: Chen Chen Vanessa G Lee Source Type: research

Looking away to see: The acquisition of a search habit away from the saccade direction
Vision Res. 2023 Jun 23;211:108276. doi: 10.1016/j.visres.2023.108276. Online ahead of print.ABSTRACTGrowing evidence has shown that attention can be habit-like, unconsciously and persistently directed toward locations that have frequently contained search targets in the past. The attentional preference typically arises when the eye gaze aligns with the attended location. Here we tested whether this spatial alignment is necessary for the acquisition of a search habit. To divert eye movements away from an attended location, we used gaze-contingent eye tracking, restricting the visible portion of the screen to an area opposi...
Source: Vision Research - June 25, 2023 Category: Opthalmology Authors: Chen Chen Vanessa G Lee Source Type: research

Looking away to see: The acquisition of a search habit away from the saccade direction
Vision Res. 2023 Jun 23;211:108276. doi: 10.1016/j.visres.2023.108276. Online ahead of print.ABSTRACTGrowing evidence has shown that attention can be habit-like, unconsciously and persistently directed toward locations that have frequently contained search targets in the past. The attentional preference typically arises when the eye gaze aligns with the attended location. Here we tested whether this spatial alignment is necessary for the acquisition of a search habit. To divert eye movements away from an attended location, we used gaze-contingent eye tracking, restricting the visible portion of the screen to an area opposi...
Source: Vision Research - June 25, 2023 Category: Opthalmology Authors: Chen Chen Vanessa G Lee Source Type: research

The duration effect of short-term monocular deprivation measured by binocular rivalry and binocular combination
Vision Res. 2023 Jun 21;211:108278. doi: 10.1016/j.visres.2023.108278. Online ahead of print.ABSTRACTThe ocular dominance shift observed after short-term monocular deprivation is a widely used measure of visual homeostatic plasticity in adult humans. Binocular rivalry and binocular combination techniques are used interchangeably to characterize homeostatic plasticity, sometimes leading to contradictory results. Here we directly compare the effect of short-term monocular deprivation on ocular dominance measured by either binocular rivalry or binocular combination and its dependence on the duration of deprivation (15 or 120 ...
Source: Vision Research - June 23, 2023 Category: Opthalmology Authors: Antoine Prosper Martina Pasqualetti Maria Concetta Morrone Claudia Lunghi Source Type: research

The duration effect of short-term monocular deprivation measured by binocular rivalry and binocular combination
Vision Res. 2023 Jun 21;211:108278. doi: 10.1016/j.visres.2023.108278. Online ahead of print.ABSTRACTThe ocular dominance shift observed after short-term monocular deprivation is a widely used measure of visual homeostatic plasticity in adult humans. Binocular rivalry and binocular combination techniques are used interchangeably to characterize homeostatic plasticity, sometimes leading to contradictory results. Here we directly compare the effect of short-term monocular deprivation on ocular dominance measured by either binocular rivalry or binocular combination and its dependence on the duration of deprivation (15 or 120 ...
Source: Vision Research - June 23, 2023 Category: Opthalmology Authors: Antoine Prosper Martina Pasqualetti Maria Concetta Morrone Claudia Lunghi Source Type: research

The duration effect of short-term monocular deprivation measured by binocular rivalry and binocular combination
Vision Res. 2023 Jun 21;211:108278. doi: 10.1016/j.visres.2023.108278. Online ahead of print.ABSTRACTThe ocular dominance shift observed after short-term monocular deprivation is a widely used measure of visual homeostatic plasticity in adult humans. Binocular rivalry and binocular combination techniques are used interchangeably to characterize homeostatic plasticity, sometimes leading to contradictory results. Here we directly compare the effect of short-term monocular deprivation on ocular dominance measured by either binocular rivalry or binocular combination and its dependence on the duration of deprivation (15 or 120 ...
Source: Vision Research - June 23, 2023 Category: Opthalmology Authors: Antoine Prosper Martina Pasqualetti Maria Concetta Morrone Claudia Lunghi Source Type: research

Targeted reaching with monocular depth information and haptic feedback: Comparing between monocular patients and normally sighted observers
Vision Res. 2023 Jun 19;211:108274. doi: 10.1016/j.visres.2023.108274. Online ahead of print.ABSTRACTMonocular blindness impairs visual depth perception, yet patients seldom report difficulties in targeted actions like reaching, walking, or driving. We hypothesized that by utilizing monocular depth information and calibrating actions with haptic feedback, monocular patients can perceive egocentric distance and perform targeted actions. We compared targeted reaching in monocular patients, monocular-viewing, and binocular-viewing normal controls. Sixty observers reached either a far or a near target, calibrating reaches to t...
Source: Vision Research - June 21, 2023 Category: Opthalmology Authors: Le Gao Zitian Liu Zidong Chen Jing S Pan Minbin Yu Source Type: research

Targeted reaching with monocular depth information and haptic feedback: Comparing between monocular patients and normally sighted observers
Vision Res. 2023 Jun 19;211:108274. doi: 10.1016/j.visres.2023.108274. Online ahead of print.ABSTRACTMonocular blindness impairs visual depth perception, yet patients seldom report difficulties in targeted actions like reaching, walking, or driving. We hypothesized that by utilizing monocular depth information and calibrating actions with haptic feedback, monocular patients can perceive egocentric distance and perform targeted actions. We compared targeted reaching in monocular patients, monocular-viewing, and binocular-viewing normal controls. Sixty observers reached either a far or a near target, calibrating reaches to t...
Source: Vision Research - June 21, 2023 Category: Opthalmology Authors: Le Gao Zitian Liu Zidong Chen Jing S Pan Minbin Yu Source Type: research

Enhanced human contrast sensitivity with increased stimulation of melanopsin in intrinsically photosensitive retinal ganglion cells
Vision Res. 2023 Jun 15;209:108271. doi: 10.1016/j.visres.2023.108271. Online ahead of print.ABSTRACTThe intrinsically photosensitive retinal ganglion cells (ipRGCs) are known to serve non-image-forming functions, such as photoentrainment of the circadian rhythm and pupillary light reflex. However, how they affect human spatial vision is largely unknown. The spatial contrast sensitivity function (CSF), which measures contrast sensitivity as a function of spatial frequency, was used in the current study to investigate the function of ipRGCs in pattern vision. To compare the effects of different background lights on the CSF,...
Source: Vision Research - June 18, 2023 Category: Opthalmology Authors: Sung-En Chien Su-Ling Yeh Wakayo Yamashita Sei-Ichi Tsujimura Source Type: research

Enhanced human contrast sensitivity with increased stimulation of melanopsin in intrinsically photosensitive retinal ganglion cells
Vision Res. 2023 Jun 15;209:108271. doi: 10.1016/j.visres.2023.108271. Online ahead of print.ABSTRACTThe intrinsically photosensitive retinal ganglion cells (ipRGCs) are known to serve non-image-forming functions, such as photoentrainment of the circadian rhythm and pupillary light reflex. However, how they affect human spatial vision is largely unknown. The spatial contrast sensitivity function (CSF), which measures contrast sensitivity as a function of spatial frequency, was used in the current study to investigate the function of ipRGCs in pattern vision. To compare the effects of different background lights on the CSF,...
Source: Vision Research - June 18, 2023 Category: Opthalmology Authors: Sung-En Chien Su-Ling Yeh Wakayo Yamashita Sei-Ichi Tsujimura Source Type: research

Enhanced human contrast sensitivity with increased stimulation of melanopsin in intrinsically photosensitive retinal ganglion cells
Vision Res. 2023 Jun 15;209:108271. doi: 10.1016/j.visres.2023.108271. Online ahead of print.ABSTRACTThe intrinsically photosensitive retinal ganglion cells (ipRGCs) are known to serve non-image-forming functions, such as photoentrainment of the circadian rhythm and pupillary light reflex. However, how they affect human spatial vision is largely unknown. The spatial contrast sensitivity function (CSF), which measures contrast sensitivity as a function of spatial frequency, was used in the current study to investigate the function of ipRGCs in pattern vision. To compare the effects of different background lights on the CSF,...
Source: Vision Research - June 18, 2023 Category: Opthalmology Authors: Sung-En Chien Su-Ling Yeh Wakayo Yamashita Sei-Ichi Tsujimura Source Type: research

Gene therapy for RAB28: What can we learn from zebrafish?
Vision Res. 2023 Jun 13;210:108270. doi: 10.1016/j.visres.2023.108270. Online ahead of print.ABSTRACTThe eye is particularly suited to gene therapy due to its accessibility, immunoprivileged state and compartmentalised structure. Indeed, many clinical trials are underway for therapeutic gene strategies for inherited retinal degenerations (IRDs). However, as there are currently 281 genes associated with IRD, there is still a large unmet need for effective therapies for the majority of IRD-causing genes. In humans, RAB28 null and hypomorphic alleles cause autosomal recessive cone-rod dystrophy (arCORD). Previous work demonst...
Source: Vision Research - June 15, 2023 Category: Opthalmology Authors: Ailis L Moran John D Fehilly Oliver Blacque Breand án N Kennedy Source Type: research

Gene therapy for RAB28: What can we learn from zebrafish?
Vision Res. 2023 Jun 13;210:108270. doi: 10.1016/j.visres.2023.108270. Online ahead of print.ABSTRACTThe eye is particularly suited to gene therapy due to its accessibility, immunoprivileged state and compartmentalised structure. Indeed, many clinical trials are underway for therapeutic gene strategies for inherited retinal degenerations (IRDs). However, as there are currently 281 genes associated with IRD, there is still a large unmet need for effective therapies for the majority of IRD-causing genes. In humans, RAB28 null and hypomorphic alleles cause autosomal recessive cone-rod dystrophy (arCORD). Previous work demonst...
Source: Vision Research - June 15, 2023 Category: Opthalmology Authors: Ailis L Moran John D Fehilly Oliver Blacque Breand án N Kennedy Source Type: research

Gene therapy for RAB28: What can we learn from zebrafish?
Vision Res. 2023 Jun 13;210:108270. doi: 10.1016/j.visres.2023.108270. Online ahead of print.ABSTRACTThe eye is particularly suited to gene therapy due to its accessibility, immunoprivileged state and compartmentalised structure. Indeed, many clinical trials are underway for therapeutic gene strategies for inherited retinal degenerations (IRDs). However, as there are currently 281 genes associated with IRD, there is still a large unmet need for effective therapies for the majority of IRD-causing genes. In humans, RAB28 null and hypomorphic alleles cause autosomal recessive cone-rod dystrophy (arCORD). Previous work demonst...
Source: Vision Research - June 15, 2023 Category: Opthalmology Authors: Ailis L Moran John D Fehilly Oliver Blacque Breand án N Kennedy Source Type: research