Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Impact of monocular vs. binocular contrast and blur on the range of functional stereopsis
Vision Res. 2023 Aug 16;212:108309. doi: 10.1016/j.visres.2023.108309. Online ahead of print.ABSTRACTStereopsis depends on the smallest stereo threshold (lower limit) and the upper fusion limit. While studies have shown that the lower limit worsens with reduced contrast and blur, more strongly in monocular than in binocular conditions, the effect on the upper limit remains uncertain. Here, we assess the impact of contrast and blur on the range of the disparity sensitivity function (DSF) in a stereo letter recognition task. Subjects had to identify the stereo letters embedded in a random dot stereogram, and adaptive stairca...
Source: Vision Research - August 18, 2023 Category: Opthalmology Authors: Wei Hau Lew Daniel R Coates Source Type: research
Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B
Vision Res. 2023 Aug 14;212:108311. doi: 10.1016/j.visres.2023.108311. Online ahead of print.ABSTRACTUsher syndrome type 1B (USH1B) is a deaf-blindness disorder, caused by mutations in the MYO7A gene, which encodes the heavy chain of an unconventional actin-based motor protein. Here, we examined the two retinal isoforms of MYO7A, IF1 and IF2. We compared 3D models of the two isoforms and noted that the 38-amino acid region that is present in IF1 but absent from IF2 affects the C lobe of the FERM1 domain and the opening of a cleft in this potentially important protein binding domain. Expression of each of the two isoforms o...
Source: Vision Research - August 16, 2023 Category: Opthalmology Authors: W Blake Gilmore Nan W Hultgren Abhishek Chadha Sonia B Barocio Joyce Zhang Oksana Kutsyr Miguel Flores-Bellver M Valeria Canto-Soler David S Williams Source Type: research
Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B
Vision Res. 2023 Aug 14;212:108311. doi: 10.1016/j.visres.2023.108311. Online ahead of print.ABSTRACTUsher syndrome type 1B (USH1B) is a deaf-blindness disorder, caused by mutations in the MYO7A gene, which encodes the heavy chain of an unconventional actin-based motor protein. Here, we examined the two retinal isoforms of MYO7A, IF1 and IF2. We compared 3D models of the two isoforms and noted that the 38-amino acid region that is present in IF1 but absent from IF2 affects the C lobe of the FERM1 domain and the opening of a cleft in this potentially important protein binding domain. Expression of each of the two isoforms o...
Source: Vision Research - August 16, 2023 Category: Opthalmology Authors: W Blake Gilmore Nan W Hultgren Abhishek Chadha Sonia B Barocio Joyce Zhang Oksana Kutsyr Miguel Flores-Bellver M Valeria Canto-Soler David S Williams Source Type: research
Expression of two major isoforms of MYO7A in the retina: Considerations for gene therapy of Usher syndrome type 1B
Vision Res. 2023 Aug 14;212:108311. doi: 10.1016/j.visres.2023.108311. Online ahead of print.ABSTRACTUsher syndrome type 1B (USH1B) is a deaf-blindness disorder, caused by mutations in the MYO7A gene, which encodes the heavy chain of an unconventional actin-based motor protein. Here, we examined the two retinal isoforms of MYO7A, IF1 and IF2. We compared 3D models of the two isoforms and noted that the 38-amino acid region that is present in IF1 but absent from IF2 affects the C lobe of the FERM1 domain and the opening of a cleft in this potentially important protein binding domain. Expression of each of the two isoforms o...
Source: Vision Research - August 16, 2023 Category: Opthalmology Authors: W Blake Gilmore Nan W Hultgren Abhishek Chadha Sonia B Barocio Joyce Zhang Oksana Kutsyr Miguel Flores-Bellver M Valeria Canto-Soler David S Williams Source Type: research
Suprathreshold contrast perception of resolvable high spatial frequencies remain intact in keratoconus
This study hypothesized that suprathreshold contrast perception is also impaired in keratoconus, with the impairment being predictable from the pattern of loss in threshold-level performance. Contrast detection thresholds were determined across a range of spatial frequencies in 12 cases with mild to severe keratoconus and 12 age-similar controls. These values were used to predict the contrast needed to achieve perceptual matches between reference and test spatial frequency pairs (peak of CSF Vs. 0.3x, 0.5x, 2x or 3x spatial frequency from the peak) for stimuli at 10% and 50% suprathreshold contrast. Contrast thresholds pre...
Source: Vision Research - August 15, 2023 Category: Opthalmology Authors: Preetam Kumar Pravin Krishna Vaddavalli Peter Campbell Christopher C Hull Shrikant R Bharadwaj Source Type: research
Discrimination of facial identity based on simple contrast patterns generated by shading and shadows
In this study, we measured the ability of human observers to discriminate facial identity based simply on the coarse pattern of contrast produced by the interaction between facial geometry and lighting direction. We used highly realistic 3D models of human heads to create images of faces illuminated from different horizontal and vertical directions, which were then converted to two-tone images ('Mooney faces') to isolate the coarse pattern of contrast. Participants were presented with pairs of two-tone faces and judged whether it was the same person in both images. Participants could discriminate facial identity based on t...
Source: Vision Research - August 13, 2023 Category: Opthalmology Authors: Lindsay M Peterson Tirta Susilo Colin W G Clifford Colin J Palmer Source Type: research
Discrimination of facial identity based on simple contrast patterns generated by shading and shadows
In this study, we measured the ability of human observers to discriminate facial identity based simply on the coarse pattern of contrast produced by the interaction between facial geometry and lighting direction. We used highly realistic 3D models of human heads to create images of faces illuminated from different horizontal and vertical directions, which were then converted to two-tone images ('Mooney faces') to isolate the coarse pattern of contrast. Participants were presented with pairs of two-tone faces and judged whether it was the same person in both images. Participants could discriminate facial identity based on t...
Source: Vision Research - August 13, 2023 Category: Opthalmology Authors: Lindsay M Peterson Tirta Susilo Colin W G Clifford Colin J Palmer Source Type: research
Discrimination of facial identity based on simple contrast patterns generated by shading and shadows
In this study, we measured the ability of human observers to discriminate facial identity based simply on the coarse pattern of contrast produced by the interaction between facial geometry and lighting direction. We used highly realistic 3D models of human heads to create images of faces illuminated from different horizontal and vertical directions, which were then converted to two-tone images ('Mooney faces') to isolate the coarse pattern of contrast. Participants were presented with pairs of two-tone faces and judged whether it was the same person in both images. Participants could discriminate facial identity based on t...
Source: Vision Research - August 13, 2023 Category: Opthalmology Authors: Lindsay M Peterson Tirta Susilo Colin W G Clifford Colin J Palmer Source Type: research
The influence of stereopsis on visual saliency in a proto-object based model of selective attention
Vision Res. 2023 Aug 3;212:108304. doi: 10.1016/j.visres.2023.108304. Online ahead of print.ABSTRACTSome animals including humans use stereoscopic vision which reconstructs spatial information about the environment from the disparity between images captured by eyes in two separate adjacent locations. Like other sensory information, such stereoscopic information is expected to influence attentional selection. We develop a biologically plausible model of binocular vision to study its effect on bottom-up visual attention, i.e., visual saliency. In our model, the scene is organized in terms of proto-objects on which attention ...
Source: Vision Research - August 5, 2023 Category: Opthalmology Authors: Takeshi Uejima Elena Mancinelli Ernst Niebur Ralph Etienne-Cummings Source Type: research
The influence of stereopsis on visual saliency in a proto-object based model of selective attention
Vision Res. 2023 Aug 3;212:108304. doi: 10.1016/j.visres.2023.108304. Online ahead of print.ABSTRACTSome animals including humans use stereoscopic vision which reconstructs spatial information about the environment from the disparity between images captured by eyes in two separate adjacent locations. Like other sensory information, such stereoscopic information is expected to influence attentional selection. We develop a biologically plausible model of binocular vision to study its effect on bottom-up visual attention, i.e., visual saliency. In our model, the scene is organized in terms of proto-objects on which attention ...
Source: Vision Research - August 5, 2023 Category: Opthalmology Authors: Takeshi Uejima Elena Mancinelli Ernst Niebur Ralph Etienne-Cummings Source Type: research
