Retinal response to light exposure in BEST1-mutant dogs evaluated with ultra-high resolution OCT
Vision Res. 2024 Mar 8;218:108379. doi: 10.1016/j.visres.2024.108379. Online ahead of print.ABSTRACTMutations in BEST1 cause an autosomal recessive disease in dogs where the earliest changes localize to the photoreceptor-RPE interface and show a retina-wide micro-detachment that is modulated by light exposure. The purpose of this study was to define the spatial and temporal details of the outer retina and its response to light with ultra-high resolution OCT across a range of ages and with different BEST1 mutations. Three retinal regions were selected in each eye: near the fovea-like area, near the optic nerve, both in the ...
Source: Vision Research - March 9, 2024 Category: Opthalmology Authors: Vivian Wu Malgorzata Swider Alexander Sumaroka Valerie L Dufour Joseph E Vance Tomas S Aleman Gustavo D Aguirre William A Beltran Artur V Cideciyan Source Type: research
Retinal response to light exposure in BEST1-mutant dogs evaluated with ultra-high resolution OCT
Vision Res. 2024 Mar 8;218:108379. doi: 10.1016/j.visres.2024.108379. Online ahead of print.ABSTRACTMutations in BEST1 cause an autosomal recessive disease in dogs where the earliest changes localize to the photoreceptor-RPE interface and show a retina-wide micro-detachment that is modulated by light exposure. The purpose of this study was to define the spatial and temporal details of the outer retina and its response to light with ultra-high resolution OCT across a range of ages and with different BEST1 mutations. Three retinal regions were selected in each eye: near the fovea-like area, near the optic nerve, both in the ...
Source: Vision Research - March 9, 2024 Category: Opthalmology Authors: Vivian Wu Malgorzata Swider Alexander Sumaroka Valerie L Dufour Joseph E Vance Tomas S Aleman Gustavo D Aguirre William A Beltran Artur V Cideciyan Source Type: research
Retinal response to light exposure in BEST1-mutant dogs evaluated with ultra-high resolution OCT
Vision Res. 2024 Mar 8;218:108379. doi: 10.1016/j.visres.2024.108379. Online ahead of print.ABSTRACTMutations in BEST1 cause an autosomal recessive disease in dogs where the earliest changes localize to the photoreceptor-RPE interface and show a retina-wide micro-detachment that is modulated by light exposure. The purpose of this study was to define the spatial and temporal details of the outer retina and its response to light with ultra-high resolution OCT across a range of ages and with different BEST1 mutations. Three retinal regions were selected in each eye: near the fovea-like area, near the optic nerve, both in the ...
Source: Vision Research - March 9, 2024 Category: Opthalmology Authors: Vivian Wu Malgorzata Swider Alexander Sumaroka Valerie L Dufour Joseph E Vance Tomas S Aleman Gustavo D Aguirre William A Beltran Artur V Cideciyan Source Type: research
Retinal response to light exposure in BEST1-mutant dogs evaluated with ultra-high resolution OCT
Vision Res. 2024 Mar 8;218:108379. doi: 10.1016/j.visres.2024.108379. Online ahead of print.ABSTRACTMutations in BEST1 cause an autosomal recessive disease in dogs where the earliest changes localize to the photoreceptor-RPE interface and show a retina-wide micro-detachment that is modulated by light exposure. The purpose of this study was to define the spatial and temporal details of the outer retina and its response to light with ultra-high resolution OCT across a range of ages and with different BEST1 mutations. Three retinal regions were selected in each eye: near the fovea-like area, near the optic nerve, both in the ...
Source: Vision Research - March 9, 2024 Category: Opthalmology Authors: Vivian Wu Malgorzata Swider Alexander Sumaroka Valerie L Dufour Joseph E Vance Tomas S Aleman Gustavo D Aguirre William A Beltran Artur V Cideciyan Source Type: research
Are ipRGCs involved in human color vision? Hints from physiology, psychophysics, and natural image statistics
Vision Res. 2024 Mar 7;217:108378. doi: 10.1016/j.visres.2024.108378. Online ahead of print.ABSTRACTHuman photoreceptors consist of cones, rods, and melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs). First studied in circadian regulation and pupillary control, ipRGCs project to a variety of brain centers suggesting a broader involvement beyond non-visual functions. IpRGC responses are stable, long-lasting, and with a particular codification of photoreceptor signals. In comparison with the transient and adaptive nature of cone and rod signals, ipRGCs' signaling might provide an ecological ad...
Source: Vision Research - March 8, 2024 Category: Opthalmology Authors: Pablo A Barrionuevo Mar ía L Sandoval Salinas Jos é M Fanchini Source Type: research
Are ipRGCs involved in human color vision? Hints from physiology, psychophysics, and natural image statistics
Vision Res. 2024 Mar 7;217:108378. doi: 10.1016/j.visres.2024.108378. Online ahead of print.ABSTRACTHuman photoreceptors consist of cones, rods, and melanopsin-expressing intrinsically photosensitive retinal ganglion cells (ipRGCs). First studied in circadian regulation and pupillary control, ipRGCs project to a variety of brain centers suggesting a broader involvement beyond non-visual functions. IpRGC responses are stable, long-lasting, and with a particular codification of photoreceptor signals. In comparison with the transient and adaptive nature of cone and rod signals, ipRGCs' signaling might provide an ecological ad...
Source: Vision Research - March 8, 2024 Category: Opthalmology Authors: Pablo A Barrionuevo Mar ía L Sandoval Salinas Jos é M Fanchini Source Type: research
Visual shape discrimination in goldfish, modelled with the neural circuitry of optic tectum and torus longitudinalis
Vision Res. 2024 Mar 6;217:108374. doi: 10.1016/j.visres.2024.108374. Online ahead of print.ABSTRACTThere is no satisfactory neurally-based theory as to how vertebrates that lack a neocortex discriminate even simple geometric shapes. In fishes, an intact optic tectum is necessary for such discriminations, but physiological studies of it have found nothing like the hierarchically arranged feature detecting neurons of mammalian visual cortex. Here, a neural model attempts a solution by basing shape discrimination upon the responses of only those elementary detectors (e.g. of size) that are within a focus of attention, formed...
Source: Vision Research - March 7, 2024 Category: Opthalmology Authors: D P M Northmore Source Type: research
Visual shape discrimination in goldfish, modelled with the neural circuitry of optic tectum and torus longitudinalis
Vision Res. 2024 Mar 6;217:108374. doi: 10.1016/j.visres.2024.108374. Online ahead of print.ABSTRACTThere is no satisfactory neurally-based theory as to how vertebrates that lack a neocortex discriminate even simple geometric shapes. In fishes, an intact optic tectum is necessary for such discriminations, but physiological studies of it have found nothing like the hierarchically arranged feature detecting neurons of mammalian visual cortex. Here, a neural model attempts a solution by basing shape discrimination upon the responses of only those elementary detectors (e.g. of size) that are within a focus of attention, formed...
Source: Vision Research - March 7, 2024 Category: Opthalmology Authors: D P M Northmore Source Type: research
Secondary not subordinate: Opsin localization suggests possibility for color sensitivity in salticid secondary eyes
Vision Res. 2024 Feb 29;217:108367. doi: 10.1016/j.visres.2024.108367. Online ahead of print.ABSTRACTThe principal eyes of jumping spiders (Salticidae) integrate a dual-lens system, a tiered retinal matrix with multiple photoreceptor classes and muscular control of retinal movements to form high resolution images, extract color information, and dynamically evaluate visual scenes. While much work has been done to characterize these more complex principal anterior eyes, little work has investigated the three other pairs of simpler secondary eyes: the anterior lateral eye pair and two posterior (lateral and median) pairs of e...
Source: Vision Research - March 1, 2024 Category: Opthalmology Authors: Mireille Steck Sophia J Hanscom Tom Iwanicki Jenny Y Sung David Outomuro Nathan I Morehouse Megan L Porter Source Type: research
Secondary not subordinate: Opsin localization suggests possibility for color sensitivity in salticid secondary eyes
Vision Res. 2024 Feb 29;217:108367. doi: 10.1016/j.visres.2024.108367. Online ahead of print.ABSTRACTThe principal eyes of jumping spiders (Salticidae) integrate a dual-lens system, a tiered retinal matrix with multiple photoreceptor classes and muscular control of retinal movements to form high resolution images, extract color information, and dynamically evaluate visual scenes. While much work has been done to characterize these more complex principal anterior eyes, little work has investigated the three other pairs of simpler secondary eyes: the anterior lateral eye pair and two posterior (lateral and median) pairs of e...
Source: Vision Research - March 1, 2024 Category: Opthalmology Authors: Mireille Steck Sophia J Hanscom Tom Iwanicki Jenny Y Sung David Outomuro Nathan I Morehouse Megan L Porter Source Type: research
Secondary not subordinate: Opsin localization suggests possibility for color sensitivity in salticid secondary eyes
Vision Res. 2024 Feb 29;217:108367. doi: 10.1016/j.visres.2024.108367. Online ahead of print.ABSTRACTThe principal eyes of jumping spiders (Salticidae) integrate a dual-lens system, a tiered retinal matrix with multiple photoreceptor classes and muscular control of retinal movements to form high resolution images, extract color information, and dynamically evaluate visual scenes. While much work has been done to characterize these more complex principal anterior eyes, little work has investigated the three other pairs of simpler secondary eyes: the anterior lateral eye pair and two posterior (lateral and median) pairs of e...
Source: Vision Research - March 1, 2024 Category: Opthalmology Authors: Mireille Steck Sophia J Hanscom Tom Iwanicki Jenny Y Sung David Outomuro Nathan I Morehouse Megan L Porter Source Type: research
Secondary not subordinate: Opsin localization suggests possibility for color sensitivity in salticid secondary eyes
Vision Res. 2024 Feb 29;217:108367. doi: 10.1016/j.visres.2024.108367. Online ahead of print.ABSTRACTThe principal eyes of jumping spiders (Salticidae) integrate a dual-lens system, a tiered retinal matrix with multiple photoreceptor classes and muscular control of retinal movements to form high resolution images, extract color information, and dynamically evaluate visual scenes. While much work has been done to characterize these more complex principal anterior eyes, little work has investigated the three other pairs of simpler secondary eyes: the anterior lateral eye pair and two posterior (lateral and median) pairs of e...
Source: Vision Research - March 1, 2024 Category: Opthalmology Authors: Mireille Steck Sophia J Hanscom Tom Iwanicki Jenny Y Sung David Outomuro Nathan I Morehouse Megan L Porter Source Type: research
Secondary not subordinate: Opsin localization suggests possibility for color sensitivity in salticid secondary eyes
Vision Res. 2024 Feb 29;217:108367. doi: 10.1016/j.visres.2024.108367. Online ahead of print.ABSTRACTThe principal eyes of jumping spiders (Salticidae) integrate a dual-lens system, a tiered retinal matrix with multiple photoreceptor classes and muscular control of retinal movements to form high resolution images, extract color information, and dynamically evaluate visual scenes. While much work has been done to characterize these more complex principal anterior eyes, little work has investigated the three other pairs of simpler secondary eyes: the anterior lateral eye pair and two posterior (lateral and median) pairs of e...
Source: Vision Research - March 1, 2024 Category: Opthalmology Authors: Mireille Steck Sophia J Hanscom Tom Iwanicki Jenny Y Sung David Outomuro Nathan I Morehouse Megan L Porter Source Type: research
Trichotomy revisited: A monolithic theory of attentional control
Vision Res. 2024 Feb 20;217:108366. doi: 10.1016/j.visres.2024.108366. Online ahead of print.ABSTRACTThe control of attention was long held to reflect the influence of two competing mechanisms of assigning priority, one goal-directed and the other stimulus-driven. Learning-dependent influences on the control of attention that could not be attributed to either of those two established mechanisms of control gave rise to the concept of selection history and a corresponding third mechanism of attentional control. The trichotomy framework that ensued has come to dominate theories of attentional control over the past decade, rep...
Source: Vision Research - February 22, 2024 Category: Opthalmology Authors: Brian A Anderson Source Type: research
Trichotomy revisited: A monolithic theory of attentional control
Vision Res. 2024 Feb 20;217:108366. doi: 10.1016/j.visres.2024.108366. Online ahead of print.ABSTRACTThe control of attention was long held to reflect the influence of two competing mechanisms of assigning priority, one goal-directed and the other stimulus-driven. Learning-dependent influences on the control of attention that could not be attributed to either of those two established mechanisms of control gave rise to the concept of selection history and a corresponding third mechanism of attentional control. The trichotomy framework that ensued has come to dominate theories of attentional control over the past decade, rep...
Source: Vision Research - February 22, 2024 Category: Opthalmology Authors: Brian A Anderson Source Type: research
