Calculus anuria: a urological emergency with an excellent outcome
AbstractCalculus anuria is a catastrophic condition with dire consequences if not treated promptly. The purpose of this study was to identify factors which influence the short-term outcome of patients with calculus anuria. A retrospective analysis was conducted from January 2016 to December 2021, in children up to the age of 18  years, who presented with calculus anuria and required emergency decompression at Sindh Institute of Urology and Transplantation, Pakistan. One hundred and twenty-five children were included. Majority were born to consanguineous parents and a few of them had positive family history of stone diseas...
Source: Urolithiasis - March 16, 2023 Category: Urology & Nephrology Source Type: research

What is the appropriate gravel size during ureteroscopy lithotripsy? An in vitro evaluation
AbstractTo propose the suitable diameter of calculus debris produced during flexible ureteroscopy lithotripsy (fURL). A glass tube was used to simulate the stone excretion process during Furl. Different stone diameters (0.50 –1.00 mm, 0.25–0.50 mm, and 0.10–0.25 mm) with three sizes of flexible ureteroscopy (fURS) (7.5Fr, 8.7Fr, and 9.9Fr) and ureteral access sheath (UAS) (12/14Fr) with or without negative pressure suction were employed in the experiment. The intraoperative calculi excretion (ICE) was recorded according to the stones discharged from the gap between fURS and UAS. The ICE raised significantly in thi...
Source: Urolithiasis - March 16, 2023 Category: Urology & Nephrology Source Type: research

The power of desktop scanning electron microscopy with elemental analysis for analyzing urinary stones
AbstractThe aim of this paper is to present a protocol for the routine morphocompositional study of kidney stones in a clinical setting, and to demonstrate that it is a simple and useful approach that can reliably determine the etiology of all types of kidney stones. Our routine study of kidney stones consists of a combination of stereoscopic microscopy, scanning electron microscopy, and infrared spectroscopy. The usefulness of such a procedure is demonstrated by its application to several illustrating examples. The protocol applied here is reliable and fast, and does not require multiple infrared spectroscopic analyses fo...
Source: Urolithiasis - March 15, 2023 Category: Urology & Nephrology Source Type: research

Simple, fast and inexpensive quantification of glycolate in the urine of patients with primary hyperoxaluria type 1
AbstractIn primary hyperoxaluria type 1 excessive endogenous production of oxalate and glycolate leads to increased urinary excretion of these metabolites. Although genetic testing is the most definitive and preferred diagnostic method, quantification of these metabolites is important for the diagnosis and evaluation of potential therapeutic interventions. Current metabolite quantification methods use laborious, technically highly complex and expensive liquid, gas or ion chromatography tandem mass spectrometry, which are available only in selected laboratories worldwide. Incubation of ortho-aminobenzaldehyde (oABA) with gl...
Source: Urolithiasis - March 15, 2023 Category: Urology & Nephrology Source Type: research

Health-related quality of life disparities among Hispanic/Latinx patients with nephrolithiasis
AbstractIt is documented that Hispanic/Latinx kidney stone formers have inferior health-related quality of life (HRQoL) compared to the general population. We hypothesized that socioeconomic factors drive HRQoL disparities. Specifically, we sought to determine if medical insurance type is associated with HRQoL disparities among Hispanic/Latinx stone formers. This was a prospective cohort observational study of patients with kidney stones across the University of San Diego Health Care System. Patients enrolled from June 2018 to August 2020 completed a validated Wisconsin Stone Quality of Life questionnaire (WISQoL). Patient...
Source: Urolithiasis - March 15, 2023 Category: Urology & Nephrology Source Type: research