Transactions of the American Clinical and Climatological Association Transactions of the American Clinical and Climatological Association RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

The gordon wilson lecture: rapid covid-19 vaccine development and the future of vaccinology
Trans Am Clin Climatol Assoc. 2023;133:103-105.NO ABSTRACTPMID:37701620 | PMC:PMC10493744 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Barney S Graham Source Type: research

The jeremiah metzger lecture: turning genes into medicines: highlights and hurdles in the development of gene therapy for genetic disease
Trans Am Clin Climatol Assoc. 2023;133:204-233.ABSTRACTThe journey from in vitro transfer of genes into mammalian cells to approved gene therapy products has spanned decades. This manuscript summarizes hurdles encountered and obstacles overcome in the development of successful adeno-associated viral (AAV) vectors for hemophilia B and for an inherited retinal dystrophy caused by mutations in the RPE65 gene. In the case of hemophilia B, careful analysis of the first unsuccessful attempts led to the realization that the human immune response to AAV vectors was preventing durable expression; elucidation of the response to the ...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Katherine A High Source Type: research

Deceased Members 1884 through 2022
Trans Am Clin Climatol Assoc. 2023;133:xvi-xxvii.NO ABSTRACTPMID:37701579 | PMC:PMC10493732 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

American clinical and climatological association meeting locations 1884-2022
Trans Am Clin Climatol Assoc. 2023;133:xlix-l.NO ABSTRACTPMID:37701581 | PMC:PMC10493754 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Glucocorticoids in chronic disease: the good, the bad, the bone
Trans Am Clin Climatol Assoc. 2023;133:69-80.ABSTRACTDespite the advent of more targeted therapies, glucocorticoids (steroids) remain in chronic use (defined as > 3 months or more) by an estimated 0.5% of the population. Steroids yield symptomatic benefits for systemic and local inflammation as well as disease-modifying properties in rheumatoid arthritis, the most common disorder for their chronic use. Despite their many benefits, steroids have been associated with a myriad of common side effects. Observational studies of steroid safety are limited by confounding by indication, and randomized controlled trials have been...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Kenneth G Saag Source Type: research