Transactions of the American Clinical and Climatological Association This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Eliminating the race coefficient in kidney function estimating equations: the center did hold
Trans Am Clin Climatol Assoc. 2023;133:247-261.ABSTRACTDr. Chi-yuan Hsu describes controversies surrounding the race coefficient ("if African American") in widely used kidney function estimating equations. He outlines recent research results on this topic by himself and others and comments on the relationship between activists and the academic medical community.PMID:37701614 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Chi-Yuan Hsu Source Type: research

Former Officers 1884 Through 2022
Trans Am Clin Climatol Assoc. 2023;133:viii-xiv.NO ABSTRACTPMID:37701615 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

The Jeremiah Metzger Lecture
Trans Am Clin Climatol Assoc. 2023;133:200.NO ABSTRACTPMID:37701616 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Clinical heterogeneity in the age of big data, advanced analytics, and complexity theory
Trans Am Clin Climatol Assoc. 2023;133:56-68.ABSTRACTClinical heterogeneity remains a challenge in the practice of medicine and is an underlying motivation for much of biomedical research. Unfortunately, despite an abundance of technologies capable of producing millions of discrete data elements with information about a patient's health status or disease prognosis, our ability to translate those data into meaningful improvements in understanding of clinical heterogeneity is limited. To address this gap, we have applied newer approaches to manifold learning and developed additional and complementary techniques to interrogat...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: David Herrington Yue Wang Source Type: research

The bert and peggy dupont lecture: tuberculosis and the building of the american west
Trans Am Clin Climatol Assoc. 2023;133:196-199.NO ABSTRACTPMID:37701618 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Eric J Rubin Source Type: research

The gordon wilson lecture: rapid covid-19 vaccine development and the future of vaccinology
Trans Am Clin Climatol Assoc. 2023;133:103-105.NO ABSTRACTPMID:37701620 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Barney S Graham Source Type: research

The jeremiah metzger lecture: turning genes into medicines: highlights and hurdles in the development of gene therapy for genetic disease
Trans Am Clin Climatol Assoc. 2023;133:204-233.ABSTRACTThe journey from in vitro transfer of genes into mammalian cells to approved gene therapy products has spanned decades. This manuscript summarizes hurdles encountered and obstacles overcome in the development of successful adeno-associated viral (AAV) vectors for hemophilia B and for an inherited retinal dystrophy caused by mutations in the RPE65 gene. In the case of hemophilia B, careful analysis of the first unsuccessful attempts led to the realization that the human immune response to AAV vectors was preventing durable expression; elucidation of the response to the ...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Katherine A High Source Type: research

Deceased Members 1884 through 2022
Trans Am Clin Climatol Assoc. 2023;133:xvi-xxvii.NO ABSTRACTPMID:37701579 | PMC:PMC10493732 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

American clinical and climatological association meeting locations 1884-2022
Trans Am Clin Climatol Assoc. 2023;133:xlix-l.NO ABSTRACTPMID:37701581 | PMC:PMC10493754 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Glucocorticoids in chronic disease: the good, the bad, the bone
Trans Am Clin Climatol Assoc. 2023;133:69-80.ABSTRACTDespite the advent of more targeted therapies, glucocorticoids (steroids) remain in chronic use (defined as > 3 months or more) by an estimated 0.5% of the population. Steroids yield symptomatic benefits for systemic and local inflammation as well as disease-modifying properties in rheumatoid arthritis, the most common disorder for their chronic use. Despite their many benefits, steroids have been associated with a myriad of common side effects. Observational studies of steroid safety are limited by confounding by indication, and randomized controlled trials have been...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: Kenneth G Saag Source Type: research

Present Members
Trans Am Clin Climatol Assoc. 2023;133:xli-xlviii.NO ABSTRACTPMID:37701584 | PMC:PMC10493761 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Winners of the theodore e. woodward award
Trans Am Clin Climatol Assoc. 2023;133:160-161.NO ABSTRACTPMID:37701585 | PMC:PMC10493735 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Recorder's Report
Trans Am Clin Climatol Assoc. 2023;133:lxxxii-lxxxiii.NO ABSTRACTPMID:37701586 | PMC:PMC10493751 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

The jeremiah metzger lecture
Trans Am Clin Climatol Assoc. 2023;133:201-203.NO ABSTRACTPMID:37701587 | PMC:PMC10493714 (Source: Transactions of the American Clinical and Climatological Association)
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Source Type: research

Microvascular endothelial activation/dysfunction and dysregulation of the angiopoietin-tie2 system in the pathogenesis of life-threatening infections
Trans Am Clin Climatol Assoc. 2023;133:234-246.ABSTRACTMicrovascular endothelial activation/dysfunction has emerged as an important mechanistic pathophysiological process in the development of morbidity and mortality in life-threatening infections. The angiopoietin-Tie2 system plays an integral role in the regulation of microvascular endothelial integrity. Angiopoietin-1 (Ang-1), produced by platelets and pericytes, is the cognate agonistic ligand for Tie2, promoting endothelial quiescence and inhibiting microvascular leak. Angiopoietin-2 (Ang-2), released from activated endothelial cells in Weibel-Palade bodies, competes ...
Source: Transactions of the American Clinical and Climatological Association - September 13, 2023 Category: General Medicine Authors: W Conrad Liles Source Type: research