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Concerns about the Responsiveness of Generic Measures and the Search for a “Minimally” Important Change: Today’s PRO Red Herrings
(Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - July 2, 2022 Category: International Medicine & Public Health Source Type: research

Meaningful Improvement in General Health Outcomes with Guselkumab Treatment for Psoriatic Arthritis: Patient-Reported Outcomes Measurement Information System-29 Results from a Phase 3 Study
ConclusionIn patients with active PsA, guselkumab treatment provided clinically meaningful reductions in fatigue and pain and improvement in physical function and social participation, as measured by the PROMIS-29 Profile. These improvements were maintained through 1 year.ClinicalTrials.govRegistration number, NCT03162796; Submission date 19 May 2017. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 30, 2022 Category: International Medicine & Public Health Source Type: research

Interpreting Within-Patient Changes on the EORTC QLQ-C30 and EORTC QLQ-LC13
ConclusionThis study confirms the appropriateness of the 10-point EORTC score threshold generally used by the field for interpreting within-patient changes, but the thresholds proposed from this study enhance interpretability by corresponding to only observable locations along the domain score scale. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 30, 2022 Category: International Medicine & Public Health Source Type: research

Meaningful Improvement in General Health Outcomes with Guselkumab Treatment for Psoriatic Arthritis: Patient-Reported Outcomes Measurement Information System-29 Results from a Phase 3 Study
ConclusionIn patients with active PsA, guselkumab treatment provided clinically meaningful reductions in fatigue and pain and improvement in physical function and social participation, as measured by the PROMIS-29 Profile. These improvements were maintained through 1 year.ClinicalTrials.govRegistration number, NCT03162796; Submission date 19 May 2017. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 30, 2022 Category: International Medicine & Public Health Source Type: research

Interpreting Within-Patient Changes on the EORTC QLQ-C30 and EORTC QLQ-LC13
ConclusionThis study confirms the appropriateness of the 10-point EORTC score threshold generally used by the field for interpreting within-patient changes, but the thresholds proposed from this study enhance interpretability by corresponding to only observable locations along the domain score scale. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 30, 2022 Category: International Medicine & Public Health Source Type: research

Patient-Reported Chronic Pain Intensity: More Than Meets the Eye
(Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 21, 2022 Category: International Medicine & Public Health Source Type: research

The Impact of Patient Support Programs in Europe: A Systematic Literature Review
ConclusionsThe heterogeneity of the observational studies reviewed reflects the complexity of patient support programs that are built ad hoc for specific diseases, treatments, and patients. Results suggest that patient support programs play a key role in promoting treatment effectiveness, clinical outcomes, and satisfaction. However, there is a need for standardizing the definition of patient support programs and the methods to evaluate their impact. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 21, 2022 Category: International Medicine & Public Health Source Type: research

Patient Medication Preferences for Managing Dry Eye Disease: The Importance of Medication Side Effects
ConclusionThis study showed that duration of burning/stinging was an important factor when choosing medications. Incorporating patient preferences in medication decisions can potentially improve patient acceptance of a treatment regimen. (Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 14, 2022 Category: International Medicine & Public Health Source Type: research

Patient-Reported Chronic Pain Intensity: More Than Meets the Eye
(Source: The Patient - Patient-Centered Outcomes Research)
Source: The Patient - Patient-Centered Outcomes Research - June 9, 2022 Category: International Medicine & Public Health Source Type: research

Patient-Centered Core Impact Sets: What They are and Why We Need Them
AbstractA quote attributed to Mark Twain states, “What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The growing focus on patient centricity has revealed a misalignment between what patients report as important to them about their disease and/or treatment, and the data collected in resear ch and care. Decisions across healthcare are made using an evidence base most stakeholders acknowledge is inadequate. Patients might report that what is important to them are everyday life impacts, concepts that can be very different from the more typical clinical outcomes we of...
Source: The Patient - Patient-Centered Outcomes Research - June 2, 2022 Category: International Medicine & Public Health Source Type: research