Recent Patents on Anti-Cancer Drug Discovery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Prognostic Value of Fatty Acid Metabolism-related Genes in Patients with Bladder Cancer
CONCLUSION: In this study, we demonstrated that a FAMRG prognosis biomarker is associated with the tumor immune microenvironment in patients with BLCA.PMID:38214320 | DOI:10.2174/1574892818666230516143945 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Qiuzheng Huang Zhijia Li Chao Liu Source Type: research

Integrated Single-cell and Bulk RNA Sequencing Analysis Cross Talk between Ferroptosis-related Genes and Prognosis in Oral Cavity Squamous Cell Carcinoma
CONCLUSION: We successfully constructed a novel 6 FRGs model and identified a prognostic immune cell, which can serve to predict clinical prognoses for OCSCC. Ferroptosis may be a new direction for immunotherapy of OCSCC.PMID:38214321 | DOI:10.2174/1574892818666230602112042 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Tianjun Lan Siqi Ren Huijun Hu Ruixin Wang Qian Chen Fan Wu Qiuping Xu Yanyan Li Libin Shao Liansheng Wang Xin Liu Haotian Cao Jinsong Li Source Type: research

PSMA PET/MR is a New Imaging Option for Identifying Glioma Recurrence and Predicting Prognosis
CONCLUSION: This primitive study shows multiparameter PSMA PET/MR to be useful in identifying glioma (especially GBM) recurrence by providing excellent tumor background comparison, tumor heterogeneity, recurrence prediction and prognosis information, although it did not improve the diagnostic performance compared to conventional MRI. Further and larger studies are required to define its potential clinical application in this setting.PMID:38214322 | DOI:10.2174/1574892818666230519150401 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Min Xiong Zhenghe Chen Chao Zhou Xiaochun Yang Wanming Hu Yongluo Jiang Rongliang Zheng Wei Fan Yonggao Mou Xiaoping Lin Source Type: research

From Multiple Myeloma to Acute Myeloid Leukemia: A Case Report of a 61-year-old Woman after 8 Years of Chemotherapy and Immunotherapy
CONCLUSION: In this course, disease relapses occurred twice, one of which was manifested by a light chain escape (LCE). Moreover, through the course of the disease in this patient, we review the process of clonal evolution that may be relevant.PMID:38214323 | DOI:10.2174/1574892818666230619093300 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Xue-Hang Fu Rong-Yan Guan Zoufang Huang Yun Li Guang Lu Wei-Wei Mou Jun Du Source Type: research

Chlorogenic Acid Inhibits Proliferation, Migration and Invasion of Pancreatic Cancer Cells < em > via < /em > AKT/GSK-3 β/β-catenin Signaling Pathway
CONCLUSION: Our study provides significant evidence that CA is able to inhibit the growth of pancreatic cancer via the AKT/GSK-3β/β-catenin signaling pathway.PMID:38214354 | DOI:10.2174/1574892818666230327134746 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Xiaoliang Chen Binyu Liu Jiale Tong Jianing Bo Miao Feng Lili Yin Xiukun Lin Source Type: research

Development and Evaluation of a Novel Hyaluronic Acid and Chitosan-modified Phytosome for Co-delivery of Oxymatrine and Glycyrrhizin for Combination Therapy
CONCLUSION: The delivery of OMT and GL via HA-CS-OGPs might be a promising treatment to reverse MDR in cancer therapy.PMID:38214355 | DOI:10.2174/1574892818666230215112942 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Xiaojin Chen Shuying Yu Pingping Wang XinFeng Zhao Gao Sang Source Type: research

The FJQR Has Synergistic Effect with Fluoropyrimidine in the Maintenance Treatment for HER-2 Negative Gastric Cancer
CONCLUSION: FJQR and fluoropyrimidine have synergistic effects as maintenance treatment in HER-2 negative GC, with good efficacy and safety.PMID:38214356 | DOI:10.2174/1574892818666230522161742 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Fanming Kong Lu Zhao Na Wang Dou Zhang Ziwei Wang Qingyun Mei Yongchao Yu Yingjie Jia Source Type: research

YBX1, Targeted By Microrna-382-5p, Promotes Laryngeal Squamous Cell Carcinoma Progression < em > via < /em > Modulating RAS/MAPK Signaling
CONCLUSION: Together, our results indicated that YBX1 is an important promoter of LSCC progression. And miR-382-5p/YBX1/RAS/MAPK signaling pathway can be perceived as a promising target in the treatment of LSCC.PMID:38214357 | DOI:10.2174/1574892818666230207091720 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Wen Zeng Yiyun Pan Hailong Chen Xianhua Lei Xiangmin Zhang Source Type: research

Human Chorionic Gonadotropin Regulates the Smad Signaling Pathway by Antagonizing TGF- β in Giant Cell Tumor of Bone
CONCLUSION: HCG restrained the Smad signaling pathway by antagonizing TGF-β signaling in GCTB. HCG may serve as a useful patent to treat GCTB.PMID:38214358 | PMC:PMC10804236 | DOI:10.2174/1574892818666230413082909 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Tangbing Xu Shenglin Xu Guangwen Ma Jun Chang Chi Zhang Ping Zhou Chao Wang Pengfei Xu Junjun Yang Yong Hu Yunfeng Wu Source Type: research

A Synergistic Combination of Oleanolic Acid and Apatinib to Enhance Antitumor Effect on Liver Cancer Cells and Protect against Hepatic Injury
CONCLUSION: OA can treat apatinib induced liver injury in H22 Tumor-burdened mice by enhancing the suppresssive effect of apatinib on the growth of tumor.PMID:38214359 | DOI:10.2174/1574892818666230417093208 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Juan Ren Jun Yan Faisal Raza Hajra Zafar Haopeng Wan Xue Chen Qingrong Cui Haiyang Li Xiangqi Wang Source Type: research

Circ_0070203 Promotes Epithelial-mesenchymal Transition in Ovarian Serous Cystadenocarcinoma through miR-370-3p/TGF βR2 Axis
CONCLUSION: Circ_0070203 could promote the epithelial-mesenchymal transition, invasion, and metastasis of HGSOC via regulating the miR-370-3p/TGFβR2 axis. Our findings provided a potential biomarker for HGSOC therapy.PMID:38214360 | DOI:10.2174/1574892818666230328124804 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Qiong Tang Huiting Wen Haoyue Hu Xiaoli Chen Shuxiu Xu Li Fan Longyang Liu Jing Li Source Type: research

Pulmonary Adenocarcinoma Patient with Complex Mutations on EGFR Benefits from Furmonertinib after Acquiring Gefitinib Resistance: A Case Report
CONCLUSION: Pulmonary adenocarcinoma with rare rare complex mutations in EGFR induced by gefitinib resistance and disease progression might benefit from furmonertinib treatment.PMID:38214361 | DOI:10.2174/1574892818666230316145232 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Guixian Wu Qian Chen Dongqing Lv Ling Lin Jing Huang Source Type: research

Comprehensive Bioinformatic Analysis Reveals an Autophagy-related Gene Signature for Predicting Outcome, Immune Status, and Drug Sensitivity in Hepatocellular Carcinoma
CONCLUSION: We introduce here a novel ARG-based predictive feature for HCC patients. Effective use of this signature will aid in determining a patient's prognosis and may lead to novel approaches to clinical decision-making and therapy.PMID:38204266 | DOI:10.2174/0115748928275025231213103658 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 11, 2024 Category: Cancer & Oncology Authors: Peng Liu Yan Zhou Shun Zeng Xiangjuan Chen Source Type: research

Increased SLC7A3 Expression inhibits Tumor Cell Proliferation and Predicts a Favorable Prognosis in Breast Cancer
CONCLUSION: Our findings indicate a downregulation of SLC7A3 expression in breast cancer tissues compared to adjacent breast tissues. High SLC7A3 expression could serve as a prognostic indicator for favorable outcomes in breast cancer patients due to its inhibitory effects on breast cancer cell proliferation and invasion.PMID:38204267 | DOI:10.2174/0115748928279007231130070056 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 11, 2024 Category: Cancer & Oncology Authors: Lifang He Yue Xu Jiediao Lin Stanley Lin Yukun Cui Source Type: research

Differentiation of Acute Leukemia Cells Including Cells with MLL-AF4 Rearrangements Induced by Jiyuan Oridonin A
CONCLUSION: Our results suggest that JOA may be considered a promising anti-leukemia compound to develop to surmount the differentiation block in AL patients.PMID:38204268 | DOI:10.2174/0115748928263141231204112640 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - January 11, 2024 Category: Cancer & Oncology Authors: Xueming Li Fenglian Zhang Yu Ke Hongmin Liu Zhenbo Hu Liuya Wei Source Type: research