Recent Patents on Anti-Cancer Drug Discovery This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Adverse Effects of Gefitinib on Skin and Colon in a Lung Cancer Mouse Model
CONCLUSION: The findings imply that gefitinib has negative effects on the skin and colon. Gefitinib- induced skin and colon adverse reactions in mice have been successfully modeled in this study.PMID:37723963 | DOI:10.2174/1574892818666230727143750 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - September 19, 2023 Category: Cancer & Oncology Authors: Yalei Wang Shuo Cheng Huawei Zhang Yali Zhang Chengcheng Ding Tiantian Peng Weihang Chen Ke Yang Jiani Zhang Yan Tan Xu Wang Zhaoheng Liu Peng Wei Miao Jiang Qian Hua Source Type: research

Development of a Novel Lipid Metabolism-related Gene Prognostic Signature for Patients with Colorectal Cancer
CONCLUSION: In this study, we demonstrated a lipid metabolism-related genes prognosis biomarker associated with the tumor immune micro-environment in patients with CRC.PMID:37723964 | DOI:10.2174/1574892818666230731121815 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - September 19, 2023 Category: Cancer & Oncology Authors: Jing Zhan Wei Cen Junchang Zhu Yunliang Ye Source Type: research

Research progress on the anticancer activity of plant polysaccharides
Recent Pat Anticancer Drug Discov. 2023 Sep 15. doi: 10.2174/1574892819666230915103434. Online ahead of print.ABSTRACTTumor is a serious threat to human health, with extremely high morbidity and mortality rates. However, tumor treatment is challenging, and the development of antitumor drugs has always been a significant research focus. Plant polysaccharides are known to possess various biological activities. They have many pharmacological properties such as immunomodulation, antitumor, antiviral, antioxidative, antithrombotic, and antiradiation effects, reduction of blood pressure and blood sugar levels, and protection fro...
Source: Recent Patents on Anti-Cancer Drug Discovery - September 19, 2023 Category: Cancer & Oncology Authors: Qiaoyan Liu Bo Song Sen Tong Qiuqiong Yang Huanhuan Zhao Jia Guo Xuexia Tian Renjie Chang Junzi Wu Source Type: research

TGF- β score based on silico analysis can robustly predict prognosis and immunological characteristics in lower-grade glioma: the evidence from multicenter studies
CONCLUSION: In conclusion, our findings suggest that TGF-β signaling pathway-related signatures are prognostic biomarkers in LGG and provide a novel tool for tumor microenvironment (TME) assessment.PMID:37718518 | DOI:10.2174/1574892819666230915143632 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - September 18, 2023 Category: Cancer & Oncology Authors: Weizhong Zhang Zhiyuan Yan Feng Zhao Qinggui He Hongbo Xu Source Type: research

Fatty Acid Metabolism Signature Contributes to the Molecular Diagnosis of a Malignant Gastric Cancer Subtype with Poor Prognosis and Lower Mutation Burden
CONCLUSION: Fatty acid metabolism genes affect the development of gastric adenocarcinoma and can predict the survival prognosis, tumor mutational load characteristics, and drug therapy sensitivity of STAD patients, which can help explore more effective immunotherapy targets for GC.PMID:37691229 | DOI:10.2174/1574892819666230907145036 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - September 11, 2023 Category: Cancer & Oncology Authors: Zhengwei Chen Guoxiong Cheng Source Type: research

Comprehensive genomic analysis of puerarin in inhibiting bladder urothelial carcinoma cell proliferation and migration
CONCLUSION: Our findings support the potential antitumor activity of puerarin in BUC. To the best of our knowledge, bioinformatics investigation suggests that puerarin demonstrates anticancer mechanisms via the upregulation of ITGA1, LAMA3 and 4, LAMB3, PAK2, DMD, and UTRN, all of which are involved in the proliferation and migration of bladder urothelial cancer cells.PMID:37694778 | DOI:10.2174/1574892819666230908110107 (Source: Recent Patents on Anti-Cancer Drug Discovery)
Source: Recent Patents on Anti-Cancer Drug Discovery - September 11, 2023 Category: Cancer & Oncology Authors: Yu-Yang Ma Ge-Jin Zhang Peng-Fei Liu Ying Liu Ji-Cun Ding Hao Xu Lin Hao Deng Pan Hai-Luo Wang Jing-Kai Wang Peng Xu Zhen-Duo Shi Kun Pang Source Type: research