Human Chorionic Gonadotropin Regulates the Smad Signaling Pathway by Antagonizing TGF- β in Giant Cell Tumor of Bone

CONCLUSION: HCG restrained the Smad signaling pathway by antagonizing TGF-β signaling in GCTB. HCG may serve as a useful patent to treat GCTB.PMID:38214358 | PMC:PMC10804236 | DOI:10.2174/1574892818666230413082909

Source: Recent Patents on Anti-Cancer Drug Discovery - January 12, 2024 Category: Cancer & Oncology Authors: Tangbing Xu Shenglin Xu Guangwen Ma Jun Chang Chi Zhang Ping Zhou Chao Wang Pengfei Xu Junjun Yang Yong Hu Yunfeng Wu Source Type: research